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Molekula

Molekula

Promethazine hydrochloride

SKU 22379819 CAS 58-33-3 C17H20N2S · HCl MW 320.88 Made to order Bulk quantities on request

Supplying 4,500+ customers in over 80 countries

ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need

Promethazine hydrochloride is a phenothiazine antihistamine used in the treatment of allergic reactions, nausea, and vomiting. It acts as a central nervous system depressant and is also used for sedation and antiemetic purposes. Available in powder form with a molecular weight of 320.88 g/mol, it has a CAS number of 58-33-3 and a molecular formula of C17H20N2S · HCl. Store at 2 to 8 °C. Hazard symbol: Danger. Molekula supplies Promethazine hydrochloride from research to bulk quantities with full documentation and ISO 9001:2015 traceability.

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Example image for illustration only. Other packaging and pack sizes are available.

Pricing & pack sizes

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Specifications

Property Value
Appearance White to faint yellow powder
Melting Point approximately 222°C (dec.)
Grade BP2010/ USP35
Heavy metals ≤ 10ppm
pH (10% aq. w/v) 4.0 - 5.0
Loss on Drying ≤ 0.5% (105°C)
Assay 99.0 - 101.0%
Sulphated Ash ≤ 0.1%
Identification (IR) Conforms to Reference
Identification (HPLC) Retention times conform to reference standard

Storage & handling

Property Value
Storage Temperature 2 to 8 °C
Transport Class 6.1
Packing Group III
Acidity Neutral

Identification

Property Value
SKU 22379819
CAS Number 58-33-3
IUPAC Name N,N-dimethyl-1-phenothiazin-10-ylpropan-2-amine;hydrochloride
EC Number 200-375-2
Molecular Formula C17H20N2S · HCl
Molecular Weight 320.88
Exact Mass 320.1114
SMILES CC(CN1C2=CC=CC=C2SC3=CC=CC=C31)N(C)C.Cl
InChIKey XXPDBLUZJRXNNZ-UHFFFAOYSA-N
InChI InChI=1S/C17H20N2S.ClH/c1-13(18(2)3)12-19-14-8-4-6-10-16(14)20-17-11-7-5-9-15(17)19;/h4-11,13H,12H2,1-3H3;1H
PubChem CID 6014
UN Number UN2811
REACH Code Y110
HTS Code 2934.30.2700
Tariff Code 2934309090

Safety & GHS

Danger
  • GHS pictogram — Corrosive Corrosive GHS05
  • GHS pictogram — Toxic Toxic GHS06
  • GHS pictogram — Health Hazard Health Hazard GHS07
  • GHS pictogram — Hazardous to the Environment Hazardous to the Environment GHS09

Hazard statements

  • H301 Toxic if swallowed
  • H315 Causes skin irritation
  • H317 May cause an allergic skin reaction
  • H318 Causes serious eye damage
  • H332 Harmful if inhaled
  • H335 May cause respiratory irritation
  • H411 Toxic to aquatic life with long lasting effects

Precautionary statements

  • P260 Do not breathe dust/fume/gas/mist/vapours/spray
  • P273 Avoid release to the environment
  • P280 Wear protective gloves/protective clothing/eye protection/face protection
  • P301+312 IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell
  • P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
  • P308+313 IF exposed or concerned: Get medical advice/attention

Documents

Certificate of Analysis (CoA) by batch

Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.

Synonyms

  • Diprasine
  • Fellozine
  • Ganphen
  • Plletia
  • Prometh Fortis
  • Prometh Plain
  • Promethacon
  • Promethazine Hcl
  • Promethegan
  • Remsed

Frequently asked questions

What is Promethazine hydrochloride used for?

Promethazine hydrochloride is primarily used as an antihistamine and antiemetic in pharmaceutical applications, commonly for treating allergies, nausea, and motion sickness.

What is the chemical formula and molecular weight of Promethazine hydrochloride?

The formula is C17H20N2S · HCl with a molecular weight of 320.88 g/mol.

How should Promethazine hydrochloride be stored?

It should be stored at 2 to 8 °C, protected from light and moisture.

What grade of Promethazine hydrochloride does Molekula supply?

Molekula supplies Promethazine hydrochloride in pharmaceutical grade, suitable for research and pharmaceutical manufacturing.

Can Molekula supply Promethazine hydrochloride in bulk?

Yes, Molekula can supply Promethazine hydrochloride in bulk quantities—please contact us for pricing and availability.

What documentation comes with a purchase of Promethazine hydrochloride?

Each order includes a Certificate of Analysis (CoA) and Safety Data Sheet (SDS); additional documentation can be provided upon request.

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