Molekula
Pretomanid
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Pretomanid is a synthetic antibacterial agent used in the treatment of drug-resistant tuberculosis. It functions as a nitroimidazole prodrug that inhibits bacterial cell wall synthesis. Available with a CAS number of 187235-37-6, its molecular formula is C14H12F3N3O5 and molecular weight is 359.26 g/mol. It must be stored at temperatures between -15 and -20 °C. The substance carries a warning signal word due to potential hazards. Molekula supplies Pretomanid from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.
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100 mg — £75.30 per pack ex VAT · £90.36 inc. VAT
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250 mg — £153.20 per pack ex VAT · £183.84 inc. VAT
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White to pale yellow powder |
| Water | ≤ 0.5% |
| Identification | Conforms to reference |
| Purity | 98.0-102.0% |
| Total Impurities | ≤ 1.0% |
| HPLC | The retention time of the major peak in the chromatogram of sample corresponds to that in the chromatogram of standard preparation |
| Residual Solvents: Methanol | ≤ 0.3% |
| Identification (IR) | Conforms to Reference |
| Any individual impurity | ≤ 0.1% |
| Heptane | ≤ 0.5% |
| Enantiomer | ≤ 0.15 |
| Methyl tert-butyl ether | ≤ 0.5% |
| Residual Solvents: DCM | ≤ 0.06% |
| Related substances PTM-2 | ≤ 0.15% |
| Related substances PTM-3A | ≤ 0.15% |
| Related substances PTM-IMP-2 | ≤ 0.15% |
| Related substances PTM-IMP-1 | ≤ 0.15% |
| Related substances PTM-IMP-4 | ≤ 0.15% |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | -15 to -20 °C |
| Acidity | Neutral |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| pKa | pKa = 7 |
Source: PubChem CID 456199 (DrugBank)
Identification
| Property | Value |
|---|---|
| SKU | 90037145 |
| CAS Number | 187235-37-6 |
| IUPAC Name | (6S)-2-nitro-6-[[4-(trifluoromethoxy)phenyl]methoxy]-6,7-dihydro-5H-imidazo[2,1-b][1,3]oxazine |
| Molecular Formula | C14H12F3N3O5 |
| Molecular Weight | 359.26 |
| Exact Mass | 359.0729 |
| SMILES | C1[C@@H](COC2=NC(=CN21)[N+](=O)[O-])OCC3=CC=C(C=C3)OC(F)(F)F |
| InChIKey | ZLHZLMOSPGACSZ-NSHDSACASA-N |
| InChI | InChI=1S/C14H12F3N3O5/c15-14(16,17)25-10-3-1-9(2-4-10)7-23-11-5-19-6-12(20(21)22)18-13(19)24-8-11/h1-4,6,11H,5,7-8H2/t11-/m0/s1 |
| PubChem CID | 456199 |
| REACH Code | Y110 |
| HTS Code | 29349944 |
| Tariff Code | 2934999090 |
Safety & GHS
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Health Hazard
GHS07
Hazard statements
- H302 Harmful if swallowed
- H315 Causes skin irritation
- H319 Causes serious eye irritation
- H335 May cause respiratory irritation
Precautionary statements
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+312 IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell
- P302+352 IF ON SKIN: Wash with soap and water
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
- P308+313 IF exposed or concerned: Get medical advice/attention
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Portuguese, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- (S)-PA 824
- (S)-PA 824 (Pretomanid)
- PA 824
- PA-824(Pretomanid)
- PA824 cpd
- Pretomanid (Standard)
- Pretomanid (USAN/INN)
- Pretomanid(S)-PA 824
- pretomanidum
- ZLHZLMOSPGACSZ-NSHDSACASA-N
Frequently asked questions
What is Pretomanid used for?
Pretomanid is used in the treatment of drug-resistant tuberculosis, particularly in combination with other antibiotics as part of a regimen for multidrug-resistant TB.
What is the chemical formula and molecular weight of Pretomanid?
The chemical formula of Pretomanid is C14H12F3N3O5, and its molecular weight is 359.26 g/mol.
How should Pretomanid be stored?
Pretomanid should be stored at temperatures between -15 and -20 °C to maintain stability and prevent degradation.
What grade of Pretomanid does Molekula supply?
Molekula supplies Pretomanid in research-grade quality, suitable for laboratory use and preclinical studies.
Can Molekula supply Pretomanid in bulk quantities?
Yes, Molekula can supply Pretomanid in bulk quantities—please contact our sales team for pricing and availability.
What documentation comes with a Pretomanid order?
Each order includes a Certificate of Analysis (CoA) and safety data sheet (SDS); additional documentation can be provided upon request.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.