Molekula
O-(1H-6-Chlorobenzotriazol-1-yl)-1,1,3,3-tetramethyluronium hexafluorophosphate (HCTU)
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
HCTU is a highly efficient coupling reagent used in peptide synthesis to activate carboxylic acids, enabling amide bond formation with minimal racemization. It is particularly valued for its mild reaction conditions and compatibility with sensitive functional groups. This chemical has a CAS number of 330645-87-9, a molecular formula of C11H15ClN5O PF6, and a molecular weight of 413.69. It should be stored at ambient temperatures, and it carries a signal word of warning for safety. Molekula supplies HCTU from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.
-
25 g — $58.70 per pack
-
100 g — $177.30 per pack
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | Solid |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Acidity | Neutral |
Identification
| Property | Value |
|---|---|
| SKU | 57471399 |
| CAS Number | 330645-87-9 |
| IUPAC Name | [(5-chloro-3-oxidobenzotriazol-3-ium-1-yl)-(dimethylamino)methylidene]-dimethylazanium hexafluorophosphate |
| Molecular Formula | C11H15ClN5O PF6 |
| Molecular Weight | 413.69 |
| Exact Mass | 413.0607 |
| SMILES | CN(C)C(=[N+](C)C)N1C2=C(C=C(C=C2)Cl)[N+](=N1)[O-].F[P-](F)(F)(F)(F)F |
| InChIKey | AFTGMAUNHUBGAW-UHFFFAOYSA-N |
| InChI | InChI=1S/C11H15ClN5O.F6P/c1-14(2)11(15(3)4)16-9-6-5-8(12)7-10(9)17(18)13-16;1-7(2,3,4,5)6/h5-7H,1-4H3;/q+1;-1 |
| PubChem CID | 24179320 |
| REACH Code | Y113 |
| HTS Code | 29339979 |
| Tariff Code | 2933998090 |
Safety & GHS
-
Health Hazard
GHS07
Hazard statements
- H315 Causes skin irritation
- H317 May cause an allergic skin reaction
- H319 Causes serious eye irritation
- H335 May cause respiratory irritation
Precautionary statements
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P302+352 IF ON SKIN: Wash with soap and water
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
- P333+313 IF skin irritation or a rash occurs: Get medical advice/attention
- P337+313 If eye irritation persists get medical advice/attention
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
No alternate names recorded for this product.
Frequently asked questions
What is HCTU primarily used for?
HCTU is commonly used as a coupling reagent in peptide synthesis, particularly for forming amide bonds in solid-phase peptide synthesis (SPPS).
What is the chemical formula and molecular weight of HCTU?
The formula is **C₁₁H₁₅ClN₅O·PF₆**, and the molecular weight is **413.69 g/mol**.
How should HCTU be stored?
Store HCTU at **ambient temperature** in a cool, dry place, away from direct sunlight and moisture.
What grade or purity is available for HCTU?
Molekula supplies HCTU in **analytical and synthesis-grade purity**, typically ≥98% by HPLC.
Can Molekula supply HCTU in bulk quantities?
Yes, we offer HCTU in bulk, with minimum order quantities (MOQs) starting from **100g** and scaling up to multi-kilogram quantities.
What documentation comes with an order of HCTU?
Each order includes a **Certificate of Analysis (CoA)**, Material Safety Data Sheet (MSDS), and a **batch-specific quality report** for traceability.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.