Molekula
N-Iodosuccinimide
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
N-Iodosuccinimide is a selective iodinating reagent widely used in organic synthesis to introduce iodine atoms into molecules with high efficiency and mild reaction conditions. It is particularly valuable in pharmaceutical and fine chemical production for creating iodinated intermediates. This chemical has a CAS number of 516-12-1, with the molecular formula C4H4INO2 and a molecular weight of 224.98. It requires storage between 2 to 8°C and carries a signal word of Warning for safety. Molekula supplies N-Iodosuccinimide from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.
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25 g — £38.70 per pack ex VAT · £46.44 inc. VAT
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100 g — £88.80 per pack ex VAT · £106.56 inc. VAT
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | Off-white/yellow/light brown crystalline powder |
| Melting Point | 197 - 204°C |
| Loss on Drying | 0.5% min |
| Assay | 98.0% min |
| n-bromosuccinimide (by potentiometry) | <=0.3% |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | 2 to 8 °C |
| Transport Class | 9 |
| Packing Group | III |
| Acidity | Neutral |
Identification
| Property | Value |
|---|---|
| SKU | 23668371 |
| CAS Number | 516-12-1 |
| IUPAC Name | 1-iodopyrrolidine-2,5-dione |
| EC Number | 208-221-6 |
| Molecular Formula | C4H4INO2 |
| Molecular Weight | 224.98 |
| Exact Mass | 224.9287 |
| SMILES | C1CC(=O)N(C1=O)I |
| InChIKey | LQZMLBORDGWNPD-UHFFFAOYSA-N |
| InChI | InChI=1S/C4H4INO2/c5-6-3(7)1-2-4(6)8/h1-2H2 |
| PubChem CID | 120273 |
| UN Number | UN3077 |
| REACH Code | Y110 |
| HTS Code | 29299050 |
| Tariff Code | 2929900090 |
Safety & GHS
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Health Hazard
GHS07
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Serious Health Hazard
GHS08
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Hazardous to the Environment
GHS09
Hazard statements
- H302 Harmful if swallowed
- H317 May cause an allergic skin reaction
- H319 Causes serious eye irritation
- H335 May cause respiratory irritation
- H341 Suspected of causing genetic defects
- H410 Very toxic to aquatic life with long lasting effects
Precautionary statements
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray
- P273 Avoid release to the environment
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+312 IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell
- P302+352 IF ON SKIN: Wash with soap and water
- P308+313 IF exposed or concerned: Get medical advice/attention
Documents
Safety Data Sheets (SDS)
Available in English, English (US), French, German, Italian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- 1-iodo-2,5-pyrrolidinedione
- 1-iodoazolidine-2,5-dione
- 1-Iodopyrrolidine-2,5-dione
- 2,5-Dioxo-1-iodopyrrolidine
- 2,5-Pyrrolidinedione, 1-iodo-
- N-Iodosuccinimide (NIS)
- NIS
- Succinimide, N-iodo-
- Succiniodimide
Frequently asked questions
What is N-Iodosuccinimide commonly used for?
N-Iodosuccinimide is primarily used as a mild iodinating reagent in organic synthesis, particularly for introducing iodine into organic compounds under mild conditions.
What is the molecular formula and molecular weight of N-Iodosuccinimide?
The molecular formula is **C₄H₄INO₂**, and the molecular weight is **224.98 g/mol**.
What safety classification does N-Iodosuccinimide have?
The signal word for N-Iodosuccinimide is **Warning**, indicating it requires careful handling but is not classified as highly hazardous.
How should N-Iodosuccinimide be stored?
It should be stored at **2 to 8°C** in a cool, dry place, away from light and moisture.
Does Molekula supply N-Iodosuccinimide in bulk quantities?
Yes, Molekula can supply N-Iodosuccinimide in bulk, with quantities tailored to your research or industrial needs.
What documentation comes with an order of N-Iodosuccinimide?
Each order includes a **Certificate of Analysis (CoA)**, **Material Safety Data Sheet (MSDS)**, and **batch-specific documentation** for traceability.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.