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Molekula

Molekula

Mitoxantrone dihydrochloride

SKU 24343907 CAS 70476-82-3 C22H28N4O6 · 2HCl MW 517.40 In stock Bulk quantities on request

Supplying 4,500+ customers in over 80 countries

ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need

Mitoxantrone dihydrochloride is a synthetic anthracenedione antineoplastic agent used in the treatment of certain cancers, including acute myeloid leukemia and breast cancer. It functions as a DNA intercalating agent and topoisomerase II inhibitor. Available with CAS number 70476-82-3, molecular formula C22H28N4O6 · 2HCl, and molecular weight 517.40 g/mol. Store at 2 to 8 °C. Hazard symbol: Danger. Molekula supplies Mitoxantrone dihydrochloride from research to bulk quantities with full documentation and ISO 9001:2015 traceability.

Expect a response within hours Speak to a chemist: +44 (0) 3302 000333

Example image for illustration only. Other packaging and pack sizes are available.

Pricing & pack sizes

Pack sizes & pricing

These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.

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  • 1 g — $589.00 per pack

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Specifications

Property Value
Appearance Very Dark Blue
Heavy metals ≤ 10.0ppm
pH 3.0 - 5.0
Loss on Drying ≤ 6.0%
Sulphated Ash ≤ 0.2%
Assay (HPLC) ≥ 97%
Appearance of Solution Clear and colourless
Total Impurities ≤ 2.0%
Identification (UV) λmax: 242nm, 275nm // 609nm, 663nm.
Identification (IR) Conforms to structure
Any individual impurity ⩽ 1.0%
Total alcohol ≤ 1.5%

Storage & handling

Property Value
Storage Temperature 2 to 8 °C
Transport Class 6.1
Packing Group II
Acidity Acid

Literature values

Published physical properties of the substance, not batch specifications.

Property Value
Melting Point 203-5 °C
Solubility (other solvents) Sparingly soluble in water; slightly sol in methanol; practically insoluble in acetonitrile chloroform; acetone

Source: PubChem CID 51082 (HSDB)

Identification

Property Value
SKU 24343907
CAS Number 70476-82-3
IUPAC Name 1,4-dihydroxy-5,8-bis[2-(2-hydroxyethylamino)ethylamino]anthracene-9,10-dione;dihydrochloride
EC Number 274-619-1
Molecular Formula C22H28N4O6 · 2HCl
Molecular Weight 517.40
Exact Mass 516.1542
SMILES C1=CC(=C2C(=C1NCCNCCO)C(=O)C3=C(C=CC(=C3C2=O)O)O)NCCNCCO.Cl.Cl
InChIKey ZAHQPTJLOCWVPG-UHFFFAOYSA-N
InChI InChI=1S/C22H28N4O6.2ClH/c27-11-9-23-5-7-25-13-1-2-14(26-8-6-24-10-12-28)18-17(13)21(31)19-15(29)3-4-16(30)20(19)22(18)32;;/h1-4,23-30H,5-12H2;2*1H
PubChem CID 51082
UN Number UN2811
REACH Code Y110
HTS Code 29225010
Tariff Code 2922500090

Safety & GHS

Danger
  • GHS pictogram — Toxic Toxic GHS06
  • GHS pictogram — Health Hazard Health Hazard GHS07
  • GHS pictogram — Serious Health Hazard Serious Health Hazard GHS08

Hazard statements

  • H302 Harmful if swallowed
  • H310 Fatal in contact with skin
  • H340 May cause genetic defects
  • H350 May cause cancer
  • H360 May damage fertility or the unborn child
  • H370 Causes damage to organs

Precautionary statements

  • P260 Do not breathe dust/fume/gas/mist/vapours/spray
  • P263 Avoid contact during pregnancy/while nursing
  • P280 Wear protective gloves/protective clothing/eye protection/face protection
  • P301+310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician
  • P308+313 IF exposed or concerned: Get medical advice/attention

Documents

Safety Data Sheets (SDS)

Available in English.

Certificate of Analysis (CoA) by batch

Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.

Synonyms

  • CL 232,315
  • Dihydroxyanthracenedione Dihydrochloride
  • Hydrochloride, Mitoxantrone
  • Mitoxantrone hydrochloride
  • Mitoxantroni Hydrochloridum
  • Mitozantrone hydrochloride
  • Mitroxone
  • Neotalem
  • Onkotrone
  • Pralifan

Frequently asked questions

What is Mitoxantrone dihydrochloride used for?

It is an antineoplastic agent used in the treatment of certain cancers, including acute myeloid leukemia and breast cancer.

What is the chemical formula and molecular weight of Mitoxantrone dihydrochloride?

The formula is C22H28N4O6 · 2HCl with a molecular weight of 517.40 g/mol.

How should Mitoxantrone dihydrochloride be stored?

It should be stored at 2 to 8 °C, protected from light and moisture.

What grade is available for Mitoxantrone dihydrochloride?

It is available in research grade, suitable for laboratory use.

Can Molekula supply Mitoxantrone dihydrochloride in bulk?

Yes, bulk quantities are available upon request; please contact our sales team for details.

What documentation comes with my order of Mitoxantrone dihydrochloride?

Each order includes a Certificate of Analysis and Safety Data Sheet (SDS) with the shipment.

Ready to order or need a custom pack?

Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.

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