Molekula
L-Pyroglutamic acid
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
L-Pyroglutamic acid is a naturally occurring amino acid derivative used in pharmaceutical synthesis and biochemical research. It serves as an intermediate in the production of certain drugs and is valued for its role in peptide chemistry. Available in powder form with a purity of ≥98%, it has a molecular formula of C5H7NO3, a molecular weight of 129.11 g/mol, and is stable at ambient storage conditions. It is classified as a hazardous substance with a signal word of Danger. Molekula supplies L-Pyroglutamic acid from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.
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100 g — £29.80 per pack ex VAT · £35.76 inc. VAT
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500 g — £65.00 per pack ex VAT · £78.00 inc. VAT
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1 kg — £82.00 per pack ex VAT · £98.40 inc. VAT
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White to off-white crystals or crystalline powder |
| Melting Point | 161 - 163°C |
| Loss on Drying | ≤ 0.50% |
| Chloride (Cl-) | ≤ 0.02% |
| Assay | 98.5 - 101.0% |
| Residue on Ignition | ≤ 0.20% |
| Specific optical rotation | -26 to -29° [10% NaOH] |
| Heavy Metals (Pb) | ≤ 10ppm |
| Iron (Fe) | ≤ 10ppm |
| Identification (IR) | Conforms to reference |
| Arsenic trioxide (As2O3) | ≤ 1ppm |
| Ammonium (NH4+) | ≤ 0.02% |
| Specific Optical Rotation[α]D20 | -11.0 to -11.5° (C=2, H2O) |
| Sulphates (SO4)(2-) | ≤ 0.02% |
| Glutamic acid content | ≤ 0.5% (HPLC) |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Flash Point | 53 °C |
| Acidity | Acid |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Melting Point | 184.7 °C |
Source: PubChem CID 7405 (DrugBank)
Identification
| Property | Value |
|---|---|
| SKU | 90032664 |
| CAS Number | 98-79-3 |
| IUPAC Name | (2S)-5-oxopyrrolidine-2-carboxylic acid |
| EC Number | 202-700-3 |
| Molecular Formula | C5H7NO3 |
| Molecular Weight | 129.11 |
| Exact Mass | 129.0426 |
| SMILES | C1CC(=O)N[C@@H]1C(=O)O |
| InChIKey | ODHCTXKNWHHXJC-VKHMYHEASA-N |
| InChI | InChI=1S/C5H7NO3/c7-4-2-1-3(6-4)5(8)9/h3H,1-2H2,(H,6,7)(H,8,9)/t3-/m0/s1 |
| PubChem CID | 7405 |
| REACH Code | Y110 |
| TSCA Listed | Yes |
| Tariff Code | 29337900 |
Safety & GHS
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Corrosive
GHS05
Hazard statements
- H315 Causes skin irritation
- H318 Causes serious eye damage
- H335 May cause respiratory irritation
Precautionary statements
- P260 Do not breathe dust/fume/gas/mist/vapours/spray
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P303+361 IF ON SKIN (or hair): Remove immediately all contaminated clothing. Rinse with water/shower
- P304+340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
- P308+313 IF exposed or concerned: Get medical advice/attention
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- (2S)-5-oxopyrrolidine-2-carboxylic acid
- (S)-(-)-2-Pyrrolidone-5-carboxylic acid
- 5-L-Oxoproline
- 5-oxo-L-proline
- GLUTIMIC ACID
- L-5-Oxoproline
- L-Proline, 5-oxo-
- Pidolic acid
- pyroglu
- Pyroglutamic acid
Frequently asked questions
What is L-Pyroglutamic acid used for?
L-Pyroglutamic acid is primarily used as an intermediate in the synthesis of pharmaceuticals and peptides, particularly as the N-terminal pyroglutamyl building block in peptides such as thyrotropin-releasing hormone (TRH), as a chiral starting material for asymmetric synthesis, and in the preparation of pidolate salts such as magnesium pidolate.
What is the chemical formula and molecular weight of L-Pyroglutamic acid?
The chemical formula is C5H7NO3 and the molecular weight is 129.11 g/mol.
How should L-Pyroglutamic acid be stored?
It should be stored at ambient temperature, protected from moisture and light, in a tightly sealed container.
What grade of L-Pyroglutamic acid does Molekula supply?
Molekula supplies L-Pyroglutamic acid in reagent grade, suitable for laboratory and research use.
Can Molekula supply L-Pyroglutamic acid in bulk?
Yes, Molekula can supply L-Pyroglutamic acid in bulk quantities—please contact our sales team for pricing and availability.
What documentation comes with an order of L-Pyroglutamic acid?
Each order includes a Certificate of Analysis (CoA) and Safety Data Sheet (SDS); additional documentation can be provided upon request.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.