Molekula
Indomethacin
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Indomethacin is a nonsteroidal anti-inflammatory drug (NSAID) widely used for its analgesic, anti-inflammatory, and antipyretic properties, particularly in treating conditions like arthritis, gout, and patent ductus arteriosus in premature infants. It is also utilized in research for its pharmacological effects on cyclooxygenase enzymes. This chemical has a CAS number of 53-86-1, with the molecular formula C19H16ClNO4 and a molecular weight of 357.79. It should be stored at ambient temperatures and handled with caution, as it carries a "Danger" signal word. Molekula supplies Indomethacin from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.
-
25 g — $93.40 per pack
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White or almost white yellow crystalline powder, practically insoluble in water, sparingly soluble in alcohol. |
| Melting Point | 158 ºC ~ 162 ºC |
| Heavy metals | ≤20 ppm |
| Identification | Conforms to reference |
| Loss on Drying | ≤0.5% |
| Chloride (Cl-) | ≤0.02% |
| Assay | ≥99.0% |
| Sulphated Ash | ≤0.1% |
| Related Substances | ≤0.5% |
| Absorption | 170 ~ 190 at 318 nm |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Transport Class | 6.1 |
| Packing Group | I |
| Acidity | Neutral |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Appearance | Pale-yellow to yellow-tan, crystalline powder |
| Odour | Odorless, or has slight odor |
| Melting Point | 158 °C |
| Water Solubility | 0.937 mg/L at 25 °C |
| Solubility (other solvents) | Soluble in ethanol, ether, acetone, castor oil; practically insoluble in water |
| pKa | pKa = 4.5 |
| log P (octanol/water) | 0.91 |
Source: PubChem CID 3715 (HSDB, Human Metabolome Database (HMDB), DrugBank)
Identification
| Property | Value |
|---|---|
| SKU | 62725591 |
| CAS Number | 53-86-1 |
| IUPAC Name | 2-[1-(4-chlorobenzoyl)-5-methoxy-2-methylindol-3-yl]acetic acid |
| EC Number | 200-186-5 |
| Molecular Formula | C19H16ClNO4 |
| Molecular Weight | 357.79 |
| Exact Mass | 357.0768 |
| SMILES | CC1=C(C2=C(N1C(=O)C3=CC=C(C=C3)Cl)C=CC(=C2)OC)CC(=O)O |
| InChIKey | CGIGDMFJXJATDK-UHFFFAOYSA-N |
| InChI | InChI=1S/C19H16ClNO4/c1-11-15(10-18(22)23)16-9-14(25-2)7-8-17(16)21(11)19(24)12-3-5-13(20)6-4-12/h3-9H,10H2,1-2H3,(H,22,23) |
| PubChem CID | 3715 |
| UN Number | UN2811 |
| REACH Code | Y110 |
| TSCA Listed | Yes |
| HTS Code | 29339997 |
| Tariff Code | 2933998090 |
Safety & GHS
-
Toxic
GHS06
-
Health Hazard
GHS07
-
Serious Health Hazard
GHS08
Hazard statements
- H300 Fatal if swallowed
- H317 May cause an allergic skin reaction
- H360 May damage fertility or the unborn child
Precautionary statements
- P201 Obtain special instructions before use
- P263 Avoid contact during pregnancy/while nursing
- P264 Wash thoroughly after handling
- P270 Do not eat, drink or smoke when using this product
- P301+310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician
- P302+352 IF ON SKIN: Wash with soap and water
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Russian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- Idomethine
- Imbrilon
- Indocid
- indometacin
- Indometacine
- Indomethacine
- Indomethazine
- Metindol
- Mikametan
- Reumacide
Frequently asked questions
What is indomethacin commonly used for?
Indomethacin is primarily used as a nonsteroidal anti-inflammatory drug (NSAID) for treating pain, inflammation, and stiffness caused by conditions like arthritis, gout, and ankylosing spondylitis.
What is the chemical formula and molecular weight of indomethacin?
The chemical formula is **C₁₉H₁₆ClNO₄**, and the molecular weight is **357.79 g/mol**.
How should indomethacin be stored?
Store indomethacin at **ambient temperature** in a dry, well-ventilated area, away from direct sunlight and moisture.
What grades or purity levels of indomethacin does Molekula supply?
Molekula supplies **pharmaceutical-grade (USP/EP/BP compliant)** indomethacin for research and development purposes.
Can Molekula supply indomethacin in bulk quantities?
Yes, Molekula can provide indomethacin in **bulk quantities** upon request, subject to availability and regulatory compliance.
What documentation comes with an order of indomethacin?
Each order includes a **Certificate of Analysis (CoA)**, **Material Safety Data Sheet (MSDS)**, and **batch-specific documentation** for traceability.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.