Molekula
Hydroxyzine dihydrochloride
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Hydroxyzine dihydrochloride is a potent antihistamine and anxiolytic compound used primarily in pharmaceutical formulations to treat allergies, itching, and anxiety. It functions as a first-generation H1-receptor antagonist and is also used as a sedative in veterinary medicine. This chemical has a CAS number of 2192-20-3, with the molecular formula C21H27ClN2O2·2HCl and a molecular weight of 447.83. It must be stored between 2 and 8°C and carries a "Danger" signal word due to its toxicity. Molekula supplies Hydroxyzine dihydrochloride from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
Pack sizes & pricing
Pricing on request — packs available from research to bulk quantities.
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White powder |
| Melting Point | ~ 200 °C |
| Heavy metals | ≤ 0.002 % |
| Loss on Drying | ≤ 5% |
| Solubility | Very soluble in water, soluble in chloroform, slightly soluble in acetone, practically insoluble in ether |
| Ethanol | ≤ 0.5 % |
| Residue on Ignition | ≤ 0.5 % |
| Total Impurities | ≤ 1.5 % |
| Toluene | ≤ 0.089 % |
| Assay (dried basis) | 98 - 102 % |
| Any impurity | ≤ 0.3 % |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | 2 to 8 °C |
| Transport Class | 8 |
| Packing Group | I |
| Acidity | Acid |
Identification
| Property | Value |
|---|---|
| SKU | 46802283 |
| CAS Number | 2192-20-3 |
| IUPAC Name | 2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]ethanol;dihydrochloride |
| EC Number | 218-586-3 |
| Molecular Formula | C21H27ClN2O2 · 2HCl |
| Molecular Weight | 447.83 |
| Exact Mass | 446.1295 |
| SMILES | C1CN(CCN1CCOCCO)C(C2=CC=CC=C2)C3=CC=C(C=C3)Cl.Cl.Cl |
| InChIKey | ANOMHKZSQFYSBR-UHFFFAOYSA-N |
| InChI | InChI=1S/C21H27ClN2O2.2ClH/c22-20-8-6-19(7-9-20)21(18-4-2-1-3-5-18)24-12-10-23(11-13-24)14-16-26-17-15-25;;/h1-9,21,25H,10-17H2;2*1H |
| PubChem CID | 91513 |
| UN Number | UN3261 |
| REACH Code | Y110 |
| TSCA Listed | Yes |
| HTS Code | 2933.59.95.00 |
| Tariff Code | 2933599590 |
Safety & GHS
-
Corrosive
GHS05
-
Health Hazard
GHS07
-
Serious Health Hazard
GHS08
Hazard statements
- H302 Harmful if swallowed
- H314 (sub cat. 1A) Causes severe skin burns and eye damage
- H336 May cause drowsiness or dizziness
- H361d Suspected of damaging fertility. Suspected of damaging the unborn child.
- H371 May cause damage to organs
Precautionary statements
- P260 Do not breathe dust/fume/gas/mist/vapours/spray
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician
- P303+361 IF ON SKIN (or hair): Remove immediately all contaminated clothing. Rinse with water/shower
- P304+340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Portuguese, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- Alamon
- Anxanil
- Atarax dihydrochloride
- Atranine A
- HYDROXIZINE CHLORIDE
- Hydroxyzine Hcl
- Hydroxyzine hydrochloride
- Hyzine-50
- Orgatrax
- Ucerax
Frequently asked questions
What is hydroxyzine dihydrochloride commonly used for?
Hydroxyzine dihydrochloride is primarily used as an antihistamine and anxiolytic, often prescribed for allergic reactions, anxiety, and sedation.
What is the chemical formula and molecular weight of hydroxyzine dihydrochloride?
The chemical formula is **C₂₁H₂₇ClN₂O₂·2HCl**, and the molecular weight is **447.83 g/mol**.
How should hydroxyzine dihydrochloride be stored?
Store at **2 to 8°C** to maintain stability and potency.
What grades or purity levels of hydroxyzine dihydrochloride does Molekula supply?
Molekula supplies **pharmaceutical-grade hydroxyzine dihydrochloride** meeting USP/EP/BP standards.
Can Molekula supply hydroxyzine dihydrochloride in bulk quantities?
Yes, we offer bulk supply options for hydroxyzine dihydrochloride, with flexible packaging (e.g., drums, bottles) based on order volume.
What documentation comes with an order of hydroxyzine dihydrochloride?
Each order includes a **Certificate of Analysis (CoA)**, **Material Safety Data Sheet (MSDS)**, and **batch-specific documentation** for traceability.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.