Molekula
Hydrochlorothiazide - USP CRS
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Hydrochlorothiazide (HCTZ) is a thiazide diuretic used primarily to treat hypertension and edema by promoting the excretion of water and electrolytes. It is also employed in managing conditions like heart failure and kidney disorders. This USP Certified Reference Standard (CRS) has a CAS number of 58-93-5, a molecular formula of C7H8ClN3O4S2, and a molecular weight of 297.74. It is stored at ambient conditions and carries a signal word of Danger due to its hazardous properties. Molekula supplies Hydrochlorothiazide - USP CRS from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
Pack sizes & pricing
Pricing on request — packs available from research to bulk quantities.
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Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | Solid |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Acidity | Neutral |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Appearance | White, or practically white crystalline powder |
| Odour | Practically odorless |
| Melting Point | 273-275 °C |
| Density | 1.693 g/cm³ |
| Water Solubility | 722 mg/L at 25 °C |
| pKa | pKa = 7.9 |
| log P (octanol/water) | -0.07 |
Source: PubChem CID 3639 (HSDB, DrugBank)
Identification
| Property | Value |
|---|---|
| SKU | 90033333 |
| CAS Number | 58-93-5 |
| IUPAC Name | 6-chloro-1,1-dioxo-3,4-dihydro-2H-1lambda6,2,4-benzothiadiazine-7-sulfonamide |
| EC Number | 200-403-3 |
| Molecular Formula | C7H8ClN3O4S2 |
| Molecular Weight | 297.74 |
| Exact Mass | 296.9645 |
| SMILES | C1NC2=CC(=C(C=C2S(=O)(=O)N1)S(=O)(=O)N)Cl |
| InChIKey | JZUFKLXOESDKRF-UHFFFAOYSA-N |
| InChI | InChI=1S/C7H8ClN3O4S2/c8-4-1-5-7(2-6(4)16(9,12)13)17(14,15)11-3-10-5/h1-2,10-11H,3H2,(H2,9,12,13) |
| PubChem CID | 3639 |
| REACH Code | Y110 |
| TSCA Listed | Yes |
| HTS Code | 29359090 |
| Tariff Code | 2935909099 |
Safety & GHS
-
Health Hazard
GHS07
-
Serious Health Hazard
GHS08
Hazard statements
- H302 Harmful if swallowed
- H317 May cause an allergic skin reaction
- H334 May cause allergy or asthma symptoms or breathing difficulties if inhaled
- H341 Suspected of causing genetic defects
- H351 Suspected of causing cancer
- H373 May cause damage to organs through prolonged or repeated exposure
Precautionary statements
- P260 Do not breathe dust/fume/gas/mist/vapours/spray
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+312 IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell
- P303+361 IF ON SKIN (or hair): Remove immediately all contaminated clothing. Rinse with water/shower
- P304+340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing
- P309+311 IF exposed or you feel unwell: Call a POISON CENTER or doctor/physician
- P501 Dispose of contents/container to an approved waste disposal plant
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Portuguese, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- Esidrix
- HCTZ
- Hidrotiazida
- hydrochlorothiazide
- Hypothiazide
- Idrotiazide
- Megadiuril
- Newtolide
- Servithiazid
- Vetidrex
Frequently asked questions
What is hydrochlorothiazide (HCTZ) USP CRS commonly used for?
Hydrochlorothiazide USP CRS is primarily used as a diuretic (water pill) to treat high blood pressure (hypertension) and fluid retention (edema) caused by conditions like heart failure or kidney disorders.
What is the chemical formula and molecular weight of hydrochlorothiazide?
The chemical formula is **C₇H₈ClN₃O₄S₂**, and the molecular weight is **297.74 g/mol**.
How should hydrochlorothiazide USP CRS be stored?
Store in a tightly sealed container at **ambient temperature**, away from moisture and direct sunlight.
What grade of hydrochlorothiazide does Molekula supply, and is USP CRS available in bulk?
Molekula supplies **USP CRS grade** hydrochlorothiazide, and **bulk quantities are available**—please contact us for pricing and lead times.
What safety classification does hydrochlorothiazide USP CRS have, and what hazards should I be aware of?
The **signal word is 'Danger'** due to potential health hazards if ingested or inhaled; handle with appropriate PPE and avoid skin/eye contact.
What documentation comes with an order of hydrochlorothiazide USP CRS from Molekula?
Each order includes a **Certificate of Analysis (CoA)**, **Safety Data Sheet (SDS)**, and **USP compliance documentation** for traceability.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.