Molekula
Guanidine thiocyanate
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Guanidine thiocyanate (CAS 593-84-0) is a highly effective chaotropic agent used primarily in molecular biology to disrupt hydrogen bonding in nucleic acids, facilitating RNA and protein extraction during sample preparation. It appears as a white to off-white crystalline solid with a molecular formula of CH₅N₃·CHNS and a molecular weight of 118.16 g/mol. Store at ambient conditions under dry conditions. The substance carries a Danger signal word due to its toxicity and corrosive properties. Molekula supplies Guanidine thiocyanate from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Often bought together
Pricing & pack sizes
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.
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100 g — £32.50 per pack ex VAT · £39.00 inc. VAT
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500 g — £93.30 per pack ex VAT · £111.96 inc. VAT
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White to off-white crystalline powder |
| Melting Point | 115 - 121°C |
| Chloride (Cl-) | ≤1% |
| Assay | ⩾ 99.0% |
| Water (KF) | ≤0.5% |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Transport Class | 8 |
| Packing Group | III |
| Acidity | Neutral |
Identification
| Property | Value |
|---|---|
| SKU | 22370205 |
| CAS Number | 593-84-0 |
| IUPAC Name | guanidine;thiocyanic acid |
| EC Number | 209-812-1 |
| Molecular Formula | CH5N3 · CHNS |
| Molecular Weight | 118.16 |
| Exact Mass | 118.0313 |
| SMILES | C(#N)S.C(=N)(N)N |
| InChIKey | ZJYYHGLJYGJLLN-UHFFFAOYSA-N |
| InChI | InChI=1S/CH5N3.CHNS/c2-1(3)4;2-1-3/h(H5,2,3,4);3H |
| PubChem CID | 65046 |
| UN Number | UN1759 |
| REACH Code | Y110 |
| TSCA Listed | Yes |
| Tariff Code | 2929900090 |
Safety & GHS
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Corrosive
GHS05
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Health Hazard
GHS07
Hazard statements
- EUH032 Contact with acids liberates very toxic gas
- EUH071 Corrosive to the respiratory tract
- H302 + H312 + H332 Harmful if swallowed, in contact with skin or if inhaled
- H314 Causes severe skin burns and eye damage
- H412 Harmful to aquatic life with long lasting effects
Precautionary statements
- P260 Do not breathe dust/fume/gas/mist/vapours/spray
- P262 Do not get in eyes, on skin, or on clothing
- P273 Avoid release to the environment
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+312 IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
Documents
Safety Data Sheets (SDS)
Available in Danish, English, English (US), French, German, Irish, Italian, Russian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- BUFFER AVL
- GTC
- Guandine thiocyanate
- guanidine isothiocyanate
- Guanidine, monothiocyanate
- guanidine;thiocyanic acid
- Guanidinium rhodanide
- Guanidinium thiocyanate
- GuSCN
- USAF EK-705
Frequently asked questions
What is guanidine thiocyanate primarily used for?
Guanidine thiocyanate is commonly used as a chaotropic agent in molecular biology for RNA/DNA extraction, protein denaturation, and cell lysis protocols.
What is the chemical formula and molecular weight of guanidine thiocyanate?
The formula is CH₅N₃·CHNS (often represented as C₂H₆N₄S), and the molecular weight is 118.16 g/mol.
How should guanidine thiocyanate be stored?
Store at ambient temperature in a tightly sealed container, away from moisture and incompatible substances.
What grades of guanidine thiocyanate does Molekula supply?
Molekula supplies analytical and reagent-grade guanidine thiocyanate, suitable for laboratory applications.
Can Molekula supply guanidine thiocyanate in bulk quantities?
Yes, bulk quantities are available upon request—contact our sales team for custom packaging and pricing.
What documentation is provided with an order of guanidine thiocyanate?
Each order includes a Certificate of Analysis (CoA), Safety Data Sheet (SDS), and batch-specific documentation for traceability.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.