Molekula
Domperidone
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Domperidone is a dopamine antagonist used primarily as an antiemetic to prevent nausea and vomiting, and to treat gastroesophageal reflux disease (GERD). It accelerates gastric emptying and enhances lower esophageal sphincter tone. This white to off-white crystalline powder has a CAS number of 57808-66-9, molecular formula C22H24ClN5O2, and a molecular weight of 425.91. It must be stored at ambient conditions and carries a signal word of Warning. Molekula supplies Domperidone from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
Pack sizes & pricing
Pricing on request — packs available from research to bulk quantities.
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Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White powder |
| Melting Point | 244 - 248 |
| Heavy metals | <20ppm |
| Single Impurity | <0.25% |
| Loss on Drying | <0.5% |
| Solubility | Practically soluble in water, soluble in Dimethylformamide, slightly soluble in Ethanol (96%) and in methanol |
| Sulphated Ash | <0.1% |
| Total Impurities | <0.5% |
| Assay (dried basis) | 99 - 101% |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Acidity | Neutral |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Melting Point | 242.5 °C |
| pKa | pKa = 7.9 |
Source: PubChem CID 3151 (DrugBank)
Identification
| Property | Value |
|---|---|
| SKU | 90004783 |
| CAS Number | 57808-66-9 |
| IUPAC Name | 6-chloro-3-[1-[3-(2-oxo-3H-benzimidazol-1-yl)propyl]piperidin-4-yl]-1H-benzimidazol-2-one |
| EC Number | 260-968-7 |
| Molecular Formula | C22H24ClN5O2 |
| Molecular Weight | 425.91 |
| Exact Mass | 425.1619 |
| SMILES | C1CN(CCC1N2C3=C(C=C(C=C3)Cl)NC2=O)CCCN4C5=CC=CC=C5NC4=O |
| InChIKey | FGXWKSZFVQUSTL-UHFFFAOYSA-N |
| InChI | InChI=1S/C22H24ClN5O2/c23-15-6-7-20-18(14-15)25-22(30)28(20)16-8-12-26(13-9-16)10-3-11-27-19-5-2-1-4-17(19)24-21(27)29/h1-2,4-7,14,16H,3,8-13H2,(H,24,29)(H,25,30) |
| PubChem CID | 3151 |
| REACH Code | Y110 |
| HTS Code | 29333961 |
| Tariff Code | 2933399990 |
Safety & GHS
-
Serious Health Hazard
GHS08
Hazard statements
- H361 Suspected of damaging fertility or the unborn child
Precautionary statements
- P260 Do not breathe dust/fume/gas/mist/vapours/spray
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P308+313 IF exposed or concerned: Get medical advice/attention
Documents
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- Apo Domperidone
- Domilium
- Domperidon
- Domperidona
- Domperidonum
- Evoxin
- KW 5338
- Motilium
- Motilium 10
- R 33,812
Frequently asked questions
What is domperidone used for?
Domperidone is primarily used as a prokinetic agent to treat gastroesophageal reflux disease (GERD), nausea, and vomiting by increasing motility of the stomach and intestines.
What is the chemical formula and molecular weight of domperidone?
The chemical formula is **C₂₂H₂₄ClN₅O₂**, and the molecular weight is **425.91 g/mol**.
What is the signal word for domperidone under GHS classification?
The signal word for domperidone is **Warning**, indicating it presents a moderate hazard.
How should domperidone be stored?
Domperidone should be stored at **ambient temperature** in a dry, well-ventilated area, away from direct sunlight.
What grades or purity levels of domperidone does Molekula supply?
Molekula supplies domperidone in **pharmaceutical-grade (USP/EP/BP compliant) and analytical-grade purity**—contact us for specific certifications.
Can Molekula supply domperidone in bulk quantities?
Yes, Molekula can supply domperidone in bulk, with minimum order quantities and packaging options tailored to your needs—inquire for details.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.