Molekula
DL-Amethopterin hydrate
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
DL-Amethopterin hydrate is a synthetic folate antagonist used in research and pharmaceutical development, particularly in studies involving antifolate mechanisms and cancer cell metabolism. It is available with a molecular formula of C20H22N8O5, a molecular weight of 454.44 g/mol, and a CAS number of 60388-53-6. Stored at -15 to -20 °C, it is classified as Danger. Molekula supplies DL-Amethopterin hydrate from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.
-
1 g — £74.10 per pack ex VAT · £88.92 inc. VAT
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | Solid |
| Water | >10% |
| Assay | >99% |
| Optical Rotation | +20-+21 |
| Residue on Ignition | <0.5% |
| Potency | 0.4EU/mg (Endotocin) |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | -15 to -20 °C |
| Transport Class | 6.1 |
| Packing Group | III |
| Acidity | Acid |
Identification
| Property | Value |
|---|---|
| SKU | 75512800 |
| CAS Number | 60388-53-6 |
| IUPAC Name | 2-[[4-[(2,4-diaminopteridin-6-yl)methyl-methylamino]benzoyl]amino]pentanedioic acid |
| EC Number | 262-213-7 |
| Molecular Formula | C20H22N8O5 |
| Molecular Weight | 454.44 |
| Exact Mass | 454.1713 |
| SMILES | CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O |
| InChIKey | FBOZXECLQNJBKD-UHFFFAOYSA-N |
| InChI | InChI=1S/C20H22N8O5/c1-28(9-11-8-23-17-15(24-11)16(21)26-20(22)27-17)12-4-2-10(3-5-12)18(31)25-13(19(32)33)6-7-14(29)30/h2-5,8,13H,6-7,9H2,1H3,(H,25,31)(H,29,30)(H,32,33)(H4,21,22,23,26,27) |
| PubChem CID | 4112 |
| UN Number | UN2811 |
| REACH Code | Y110 |
| HTS Code | 2933.59.9500 |
| Tariff Code | 2933599590 |
Safety & GHS
-
Toxic
GHS06
-
Serious Health Hazard
GHS08
Hazard statements
- H301 Toxic if swallowed
- H315 Causes skin irritation
- H319 Causes serious eye irritation
- H360 May damage fertility or the unborn child
Precautionary statements
- P201 Obtain special instructions before use
- P263 Avoid contact during pregnancy/while nursing
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician
- P302+352 IF ON SKIN: Wash with soap and water
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
Documents
Safety Data Sheets (SDS)
Available in English, English (US), French, German, Italian, Portuguese, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- ( inverted exclamation markA)-Methotrexate
- (+/-)Amethopterin
- Amethopterin (R,S)
- DL-Amethopterin
- DL-Glutamic acid, N-(4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-
- DL-Methotrexate
- Methotrexate, (A+-)-
- Methotrexate;DL-Amethopterin
- METHOTREXATE(+/-)
- s1210
Frequently asked questions
What is DL-Amethopterin hydrate used for?
DL-Amethopterin hydrate is primarily used in research applications involving folate metabolism and as an inhibitor of dihydrofolate reductase (DHFR).
What is the chemical formula and molecular weight of DL-Amethopterin hydrate?
The chemical formula is C20H22N8O5, and the molecular weight is 454.44 g/mol.
How should DL-Amethopterin hydrate be stored?
It should be stored at temperatures between -15 and -20 °C to maintain stability.
What grade of DL-Amethopterin hydrate does Molekula supply?
Molekula supplies DL-Amethopterin hydrate in research-grade quality.
Can Molekula supply DL-Amethopterin hydrate in bulk quantities?
Yes, Molekula can supply DL-Amethopterin hydrate in bulk quantities—please contact our sales team for details.
What documentation comes with a purchase of DL-Amethopterin hydrate?
Each order includes a Certificate of Analysis (CoA) and safety documentation, including SDS.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.