Molekula
Dexamethasone - USP CRS
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Dexamethasone USP Certified Reference Standard (CRS) is a potent synthetic glucocorticoid used primarily in pharmaceutical formulations for anti-inflammatory, immunosuppressive, and antiallergic effects. It serves as a reference material for quality control in drug manufacturing and analytical testing. This product has a CAS number of 50-02-2, molecular formula C22H29FO5, and a molecular weight of 392.46. Store at 2 to 8°C, with a signal word of Danger due to its hazardous properties. Molekula supplies Dexamethasone USP CRS from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
Pack sizes & pricing
Pricing on request — packs available from research to bulk quantities.
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White or almost white crystalline powder |
| Identification | Complies with the standard |
| Acetone | ≤5000ppm |
| Loss on Drying | ≤0.5% |
| Solubility | Practically insoluble in water, sparingly soluble in anhydrous ethanol, slightly soluble in methylene chloride. |
| Methanol | ≤3000ppm |
| Specific optical rotation | +75° ~ +80° |
| Ethyl acetate | ≤5000ppm |
| Total Impurities | ≤1.0% |
| Chloroform | ≤60ppm |
| Any impurity | ≤0.5% |
| Assay (UV, basis on drying) | 97.0% ~ 103.0% |
| Dimethylformamide | ≤880ppm |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | 2 to 8 °C |
| Acidity | Acid |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Appearance | White to practically white crystalline powder |
| Melting Point | 262-264 °C |
| Water Solubility | 89 mg/L at 25 °C |
| log P (octanol/water) | 1.83 |
Source: PubChem CID 5743 (HSDB)
Identification
| Property | Value |
|---|---|
| SKU | 90035387 |
| CAS Number | 50-02-2 |
| IUPAC Name | (8S,9R,10S,11S,13S,14S,16R,17R)-9-fluoro-11,17-dihydroxy-17-(2-hydroxyacetyl)-10,13,16-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one |
| EC Number | 200-003-9 |
| Molecular Formula | C22H29FO5 |
| Molecular Weight | 392.46 |
| Exact Mass | 392.1999 |
| SMILES | C[C@@H]1C[C@H]2[C@@H]3CCC4=CC(=O)C=C[C@@]4([C@]3([C@H](C[C@@]2([C@]1(C(=O)CO)O)C)O)F)C |
| InChIKey | UREBDLICKHMUKA-CXSFZGCWSA-N |
| InChI | InChI=1S/C22H29FO5/c1-12-8-16-15-5-4-13-9-14(25)6-7-19(13,2)21(15,23)17(26)10-20(16,3)22(12,28)18(27)11-24/h6-7,9,12,15-17,24,26,28H,4-5,8,10-11H2,1-3H3/t12-,15+,16+,17+,19+,20+,21+,22+/m1/s1 |
| PubChem CID | 5743 |
| REACH Code | Y110 |
| TSCA Listed | Yes |
| HTS Code | 29372200 |
| Tariff Code | 2937220000 |
Safety & GHS
-
Serious Health Hazard
GHS08
Hazard statements
- H320 Causes eye irritation
- H361 Suspected of damaging fertility or the unborn child
- H372 Causes damage to organs through prolonged or repeated exposure
Precautionary statements
- P201 Obtain special instructions before use
- P263 Avoid contact during pregnancy/while nursing
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
- P308+313 IF exposed or concerned: Get medical advice/attention
Documents
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- Aeroseb-Dex
- Calonat
- Cortisumman
- Decaderm
- Decadron
- Dexacortal
- Dexacortin
- dexamethasone
- Fluormethylprednisolone
- Prednisolone F
Frequently asked questions
What is Dexamethasone USP CRS primarily used for?
Dexamethasone USP CRS (Certified Reference Standard) is used for analytical testing, quality control, and method validation in pharmaceutical formulations, ensuring compliance with USP standards.
What is the chemical formula and molecular weight of Dexamethasone?
The chemical formula is **C22H29FO5** and the molecular weight is **392.46 g/mol**.
How should Dexamethasone USP CRS be stored?
Store between **2 to 8°C** to maintain stability and potency.
What grade of Dexamethasone is available from Molekula?
Molekula supplies **USP Certified Reference Standard (CRS) grade** for analytical and regulatory applications.
Can Molekula supply Dexamethasone USP CRS in bulk quantities?
Yes, bulk quantities are available upon request—contact Molekula for pricing and lead times.
What documentation comes with an order of Dexamethasone USP CRS?
Each order includes a **Certificate of Analysis (CoA)**, **Safety Data Sheet (SDS)**, and **batch-specific documentation** for traceability.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.