Molekula
Dapagliflozin propanediol monohydrate
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Dapagliflozin propanediol monohydrate is a selective sodium-glucose cotransporter 2 (SGLT2) inhibitor used primarily in pharmaceutical research and development for diabetes treatment studies. It is a crystalline solid with a defined molecular structure critical for metabolic research. This chemical has a CAS number of 960404-48-2, a molecular formula of C21H25ClO6.C3H8O2.H2O, and a molecular weight of 502.99 g/mol. It must be stored at -15 to -20°C and carries a Danger signal word due to its hazardous properties. Molekula supplies Dapagliflozin propanediol monohydrate from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
Pack sizes & pricing
Pricing on request — packs available from research to bulk quantities.
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Specifications
| Property | Value |
|---|---|
| Appearance | White to off-white powder |
| Water | 3.2% - 4.0% |
| Single Impurity | ≤0.10% |
| Acetonitrile | ≤0.041% |
| Solubility | Freely soluble methanol, in tetrahydrofuran in ethanol and in acetone soluble in acetonitrile slight soluble in water. |
| Assay | 98.0% - 102.0% (C21H25CIO6) calculated on the anhydrous propanediol-free, and solvent-free basis. |
| Methanol | ≤0.30% |
| Total Impurities | ≤0.30% |
| Acetic acid | ≤0.50% |
| Identification (IR and HPLC) | IR: The infared absorption spectrum of the sample shall be consistent with that of the reference substance. HPLC: The retention time of the major peak of the sample solution coresponds to that of the standard solution as obtainded in the assay |
| Cyclohexane | ≤0.388% |
| Isopropyl acetate | ≤0.50% |
| Propanediol | 14.0% - 16.5% |
| Ethyldapagliflozin | ≤0.15% |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | -15 to -20 °C |
| Acidity | Neutral |
Identification
| Property | Value |
|---|---|
| SKU | 90037488 |
| CAS Number | 960404-48-2 |
| IUPAC Name | (2S,3R,4R,5S,6R)-2-[4-chloro-3-[(4-ethoxyphenyl)methyl]phenyl]-6-(hydroxymethyl)oxane-3,4,5-triol;(2S)-propane-1,2-diol;hydrate |
| Molecular Formula | C21H25ClO6.C3H8O2.H2O |
| Molecular Weight | 502.99 |
| Exact Mass | 502.197 |
| SMILES | CCOC1=CC=C(C=C1)CC2=C(C=CC(=C2)[C@H]3[C@@H]([C@H]([C@@H]([C@H](O3)CO)O)O)O)Cl.C[C@@H](CO)O.O |
| InChIKey | GOADIQFWSVMMRJ-UPGAGZFNSA-N |
| InChI | InChI=1S/C21H25ClO6.C3H8O2.H2O/c1-2-27-15-6-3-12(4-7-15)9-14-10-13(5-8-16(14)22)21-20(26)19(25)18(24)17(11-23)28-21;1-3(5)2-4;/h3-8,10,17-21,23-26H,2,9,11H2,1H3;3-5H,2H2,1H3;1H2/t17-,18-,19+,20-,21+;3-;/m10./s1 |
| PubChem CID | 24906252 |
| REACH Code | Y110 |
| HTS Code | 29329970 |
| Tariff Code | 2932990090 |
Safety & GHS
-
Health Hazard
GHS07
-
Serious Health Hazard
GHS08
Hazard statements
- H302 Harmful if swallowed
- H360D May harm the unborn child
- H362 May cause harm to breast-fed children
- H372 Causes damage to organs through prolonged or repeated exposure
Precautionary statements
- P260 Do not breathe dust/fume/gas/mist/vapours/spray
- P263 Avoid contact during pregnancy/while nursing
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+330 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting
- P302+352 IF ON SKIN: Wash with soap and water
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
- P308+313 IF exposed or concerned: Get medical advice/attention
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Portuguese, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- dapagliflozin (S)-propylene glycol hydrate
- DAPAGLIFLOZIN COMPOUND WITH (2S)-1,2-PROPANEDIOL HYDRATE
- Dapagliflozin propandiol monohydrate
- Dapagliflozin propanediol
- DAPAGLIFLOZIN PROPANEDIOL COMPONENT OF XIGDUO
- Dapagliflozin propanediol hydrate
- Dapagliflozin propylene glycol hydrate
- Dapagliflozin propylene glycolate hydrate
- Dapagliflozin S-propylene glycol monohydrate
- XIGDUO COMPONENT DAPAGLIFLOZIN PROPANEDIOL
Frequently asked questions
What is Dapagliflozin propanediol monohydrate used for?
It is the drug-substance form of dapagliflozin, a sodium-glucose cotransporter 2 (SGLT2) inhibitor for treating type 2 diabetes. This (S)-propylene glycol monohydrate solvate is the active ingredient in Farxiga and Xigduo.
What is the chemical formula and molecular weight?
The formula is C₂₁H₂₅ClO₆·C₃H₈O₂·H₂O, with a molecular weight of 502.99 g/mol.
How should Dapagliflozin propanediol monohydrate be stored?
Store at -15 to -20°C to maintain stability and prevent degradation.
What grade or purity is available for this compound?
Molekula supplies this compound in pharmaceutical-grade purity (≥98% HPLC), suitable for API synthesis.
Can Molekula supply this in bulk quantities?
Yes, we offer bulk quantities (from 1 kg to multi-ton orders) with flexible packaging options.
What documentation comes with the order?
Each order includes a Certificate of Analysis (CoA), Material Safety Data Sheet (MSDS), and batch-specific documentation for traceability.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.