Molekula
Colchicine
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Colchicine is a naturally occurring alkaloid used primarily in the treatment of gout and familial Mediterranean fever. In the laboratory, it is widely used in plant genetics research to induce chromosome doubling, and it is the active ingredient in prescription medicines such as Colcrys and Lodoco. It functions by inhibiting microtubule polymerization, thereby reducing inflammation. Available in powder form with a CAS number of 64-86-8, its molecular formula is C22H25NO6 and molecular weight is 399.44 g/mol. Stored at ambient temperatures, it carries a Danger signal word due to its toxicity. Molekula supplies Colchicine from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.
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1 g — £294.00 per pack ex VAT · £352.80 inc. VAT
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | Pale-yellow amorphous powder |
| Heavy metals | ≤10ppm |
| Solubility | Soluble in water, freely soluble in alcohol and chloroform, slightly soluble in ether |
| Assay | 94 - 101% |
| Particle Size | 100% pass 80 mesh |
| Fungi | ≤100cfu/g |
| Moisture | ≤2% |
| Total Bacteria Count | ≤1000cfu/g |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Transport Class | 6.1 |
| Packing Group | II |
| Acidity | Neutral |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Odour | Odorless or nearly so |
| Melting Point | 142-150 °C |
| Boiling Point | 407 °C at 760 mmHg |
| Vapour Pressure | 0.00001 mmHg at 25 °C |
| pKa | pKa = 12.36 |
| log P (octanol/water) | 1.03 |
Source: PubChem CID 6167 (HSDB, PAC Chemical Database, DrugBank)
Identification
| Property | Value |
|---|---|
| SKU | 22115544 |
| CAS Number | 64-86-8 |
| IUPAC Name | N-[(7S)-1,2,3,10-tetramethoxy-9-oxo-6,7-dihydro-5H-benzo[a]heptalen-7-yl]acetamide |
| EC Number | 200-598-5 |
| Molecular Formula | C22H25NO6 |
| Molecular Weight | 399.44 |
| Exact Mass | 399.1682 |
| SMILES | CC(=O)N[C@H]1CCC2=CC(=C(C(=C2C3=CC=C(C(=O)C=C13)OC)OC)OC)OC |
| InChIKey | IAKHMKGGTNLKSZ-INIZCTEOSA-N |
| InChI | InChI=1S/C22H25NO6/c1-12(24)23-16-8-6-13-10-19(27-3)21(28-4)22(29-5)20(13)14-7-9-18(26-2)17(25)11-15(14)16/h7,9-11,16H,6,8H2,1-5H3,(H,23,24)/t16-/m0/s1 |
| PubChem CID | 6167 |
| UN Number | UN1544 |
| REACH Code | Y110 |
| TSCA Listed | Yes |
| HTS Code | 2939.79.0090 |
| Tariff Code | 2939799090 |
Safety & GHS
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Toxic
GHS06
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Serious Health Hazard
GHS08
Hazard statements
- H300 Fatal if swallowed
- H319 Causes serious eye irritation
- H330 Fatal if inhaled
- H340 May cause genetic defects
- H361 Suspected of damaging fertility or the unborn child
Precautionary statements
- P260 Do not breathe dust/fume/gas/mist/vapours/spray
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician
- P302+352 IF ON SKIN: Wash with soap and water
- P308+313 IF exposed or concerned: Get medical advice/attention
Documents
Safety Data Sheets (SDS)
Available in English, English (US), French, German, Italian, Portuguese, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- 7-alpha-H-Colchicine
- Colchcine
- Colchicina
- Colchicinum
- Colchineos
- Colchisol
- Colcrys
- LODOCO
- Mitigare
- N-Acetyl trimethylcolchicinic acid methylether
Frequently asked questions
What is colchicine used for?
Colchicine is primarily used in the treatment and prevention of gout and familial Mediterranean fever due to its anti-inflammatory properties.
What is the chemical formula and molecular weight of colchicine?
The chemical formula of colchicine is C22H25NO6, with a molecular weight of 399.44 g/mol.
How should colchicine be stored?
Colchicine should be stored at ambient temperature, protected from light and moisture.
What grade of colchicine does Molekula supply?
Molekula supplies colchicine in research-grade purity, suitable for laboratory use.
Can Molekula supply colchicine in bulk quantities?
Yes, Molekula can supply colchicine in bulk quantities—please contact our sales team for volume pricing and availability.
What documentation comes with a colchicine order?
Each order includes a Certificate of Analysis (CoA) and Safety Data Sheet (SDS) with the shipment.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.