Molekula
Clozapine USP reference standard
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Clozapine USP reference standard is a high-purity analytical benchmark of clozapine, used for verifying the identity, potency, and purity of clozapine in pharmaceutical formulations and research applications. It meets USP monograph specifications for accurate analytical testing. CAS 5786-21-0, molecular formula C18H19ClN4, molecular weight 326.82 g/mol. Store between 2–8°C. Signal word: Danger. Molekula supplies Clozapine USP reference standard from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
Pack sizes & pricing
Pricing on request — packs available from research to bulk quantities.
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Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | pale yellow powder |
| Melting Point | 182 - 185°C |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | 2 to 8 °C |
| Flash Point | 19 °C |
| Transport Class | 6.1 |
| Packing Group | III |
| Acidity | Neutral |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Melting Point | 183-184 °C |
| pKa | pKa = 7.5 |
| log P (octanol/water) | 3.23 |
Source: PubChem CID 135398737 (HSDB, DrugBank)
Identification
| Property | Value |
|---|---|
| SKU | 90032812 |
| CAS Number | 5786-21-0 |
| IUPAC Name | 3-chloro-6-(4-methylpiperazin-1-yl)-11H-benzo[b][1,4]benzodiazepine |
| EC Number | 227-313-7 |
| Molecular Formula | C18H19ClN4 |
| Molecular Weight | 326.82 |
| Exact Mass | 326.1298 |
| SMILES | CN1CCN(CC1)C2=NC3=C(C=CC(=C3)Cl)NC4=CC=CC=C42 |
| InChIKey | QZUDBNBUXVUHMW-UHFFFAOYSA-N |
| InChI | InChI=1S/C18H19ClN4/c1-22-8-10-23(11-9-22)18-14-4-2-3-5-15(14)20-16-7-6-13(19)12-17(16)21-18/h2-7,12,20H,8-11H2,1H3 |
| PubChem CID | 135398737 |
| UN Number | UN2811 |
| REACH Code | Y110 |
| HTS Code | 29335995 |
| Tariff Code | 2933599590 |
Safety & GHS
-
Toxic
GHS06
-
Serious Health Hazard
GHS08
-
Hazardous to the Environment
GHS09
Hazard statements
- H301 Toxic if swallowed
- H341 Suspected of causing genetic defects
- H361 Suspected of damaging fertility or the unborn child
- H372 Causes damage to organs through prolonged or repeated exposure
- H411 Toxic to aquatic life with long lasting effects
Precautionary statements
- P201 Obtain special instructions before use
- P263 Avoid contact during pregnancy/while nursing
- P273 Avoid release to the environment
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician
- P501 Dispose of contents/container to an approved waste disposal plant
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- 8-Chloro-11-(4-methyl-1-piperazinyl)-5H-dibenzo[b,e][1,4]diazepine
- Clorazil
- Clozapin
- Clozapina
- clozapine
- Clozapinum
- CLOZARIL
- Fazaclo
- Fazaclo ODT
- Leponex
Frequently asked questions
What is Clozapine USP reference standard used for?
This USP reference standard is primarily used for analytical testing, calibration of instruments, and quality control in pharmaceutical manufacturing to ensure clozapine meets regulatory specifications.
What is the chemical formula and molecular weight of Clozapine?
The chemical formula is **C18H19ClN4**, and the molecular weight is **326.82 g/mol**.
How should Clozapine USP reference standard be stored?
Store between **2–8°C** to maintain stability and potency.
What grade of Clozapine is this, and is it suitable for pharmaceutical applications?
This is a **USP reference standard grade**, meeting strict purity and documentation requirements for pharmaceutical use.
Can Molekula supply Clozapine USP reference standard in bulk quantities?
Bulk quantities may be available upon request—please contact our sales team for pricing and availability.
What documentation comes with the order of Clozapine USP reference standard?
Each order includes a **Certificate of Analysis (CoA)**, batch-specific documentation, and a Material Safety Data Sheet (MSDS).
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.