Molekula
Bis(trimethylsilyl)trifluoroacetamide
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Bis(trimethylsilyl)trifluoroacetamide is a silylating agent used in organic synthesis, particularly for derivatizing alcohols, amines, and carboxylic acids in analytical chemistry and pharmaceutical research. It is a colorless to pale yellow liquid with a molecular weight of 257.40 g/mol, CAS number 25561-30-2, and molecular formula CF3C[=NSi(CH3)3]OSi(CH3)3. Store at ambient temperature. Signal word: Danger. Molekula supplies Bis(trimethylsilyl)trifluoroacetamide from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.
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1 g — £22.40 per pack ex VAT · £26.88 inc. VAT
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25 g — £126.90 per pack ex VAT · £152.28 inc. VAT
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | Colourless transparent liquid |
| Boiling Point | 64 - 66 Deg C |
| Identification | Conforms to reference |
| Assay | ≥98% |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Flash Point | 24 °C |
| Transport Class | 3 |
| Packing Group | II |
| Acidity | Base |
Identification
| Property | Value |
|---|---|
| SKU | 14757349 |
| CAS Number | 25561-30-2 |
| IUPAC Name | trimethylsilyl 2,2,2-trifluoro-N-trimethylsilylethanimidate |
| EC Number | 247-103-9 |
| Molecular Formula | CF3C[=NSi(CH3)3]OSi(CH3)3 |
| Molecular Weight | 257.40 |
| Exact Mass | 257.0879 |
| SMILES | C[Si](C)(C)N=C(C(F)(F)F)O[Si](C)(C)C |
| InChIKey | XCOBLONWWXQEBS-UHFFFAOYSA-N |
| InChI | InChI=1S/C8H18F3NOSi2/c1-14(2,3)12-7(8(9,10)11)13-15(4,5)6/h1-6H3 |
| PubChem CID | 94358 |
| UN Number | UN1993 |
| REACH Code | Y110 |
| HTS Code | 29319090 |
| Tariff Code | 2931900090 |
Safety & GHS
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Flammable
GHS02
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Health Hazard
GHS07
Hazard statements
- H226 Flammable liquid and vapour
- H315 Causes skin irritation
- H319 Causes serious eye irritation
Precautionary statements
- P210 Keep away from heat/sparks/open flames/hot surfaces - No smoking
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P302+352 IF ON SKIN: Wash with soap and water
- P303+361 IF ON SKIN (or hair): Remove immediately all contaminated clothing. Rinse with water/shower
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- Acetamide, 2,2,2-trifluoro-O,N-bis(trimethylsilyl)-
- BSTFA
- BSTFA + TMCS
- BSTFA; N,O-Bis(trimethylsilyl)trifluoroacetamide
- C8H18F3NOSi2
- Ethanimidic acid, 2,2,2-trifluoro-N-(trimethylsilyl)-, trimethylsilyl ester
- N,O-bis(TMS)3FAN
- N,O-Bis(trimethylsilyl)trifluoroacetamide
- Trimethylsilyl 2,2,2-trifluoro-N-(trimethylsilyl)acetimidate
- trimethylsilyl 2,2,2-trifluoro-N-trimethylsilylethanimidate
Frequently asked questions
What is Bis(trimethylsilyl)trifluoroacetamide used for?
It is primarily used as a silylating agent in organic synthesis, particularly for the derivatization of alcohols, amines, and carboxylic acids in analytical chemistry and pharmaceutical research.
What is the chemical formula and molecular weight?
The formula is CF3C[=NSi(CH3)3]OSi(CH3)3 with a molecular weight of 257.40 g/mol.
How should it be stored?
It should be stored at ambient temperature, protected from moisture and heat, in a tightly sealed container.
What grade is available?
Available in high-purity analytical grade, suitable for laboratory and research applications.
Can Molekula supply it in bulk?
Yes, Molekula can supply Bis(trimethylsilyl)trifluoroacetamide in bulk quantities—please contact our sales team for pricing and availability.
What documentation comes with the order?
Each order includes a Certificate of Analysis (CoA) and Safety Data Sheet (SDS); additional documentation can be provided upon request.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.