Molekula
Benzotriazole-1-yl-oxy-tris-pyrrolidino-phosphonium hexafluorophosphate
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Benzotriazole-1-yl-oxy-tris-pyrrolidino-phosphonium hexafluorophosphate (PyBOP) is a widely used coupling reagent in peptide synthesis, enabling efficient amide bond formation under mild conditions. It is also employed in organic synthesis for activating carboxyl groups in esterifications and other transformations. This chemical has a CAS number of 128625-52-5, with the molecular formula C18H28N6OP·PF6 and a molecular weight of 520.39. It is stored at ambient conditions and carries a warning signal word for safety. Molekula supplies PyBOP from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.
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5 g — $58.70 per pack
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25 g — $177.60 per pack
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
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Specifications
| Property | Value |
|---|---|
| Appearance | White crystalline powder |
| Melting Point | 150 - 158℃ |
| Loss on Drying | ≤0.5% |
| Assay HPLC | ≥99.0% |
| Solubility (20°C) | 28.0% (wt./vol.) in DMF. |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Transport Class | 9 |
| Packing Group | III |
| Acidity | Neutral |
Identification
| Property | Value |
|---|---|
| SKU | 26747821 |
| CAS Number | 128625-52-5 |
| IUPAC Name | benzotriazol-1-yloxy(tripyrrolidin-1-yl)phosphanium hexafluorophosphate |
| Molecular Formula | C18H28N6OP·PF6 |
| Molecular Weight | 520.39 |
| Exact Mass | 520.1704 |
| SMILES | C1CCN(C1)[P+](N2CCCC2)(N3CCCC3)ON4C5=CC=CC=C5N=N4.F[P-](F)(F)(F)(F)F |
| InChIKey | VIAFLMPQBHAMLI-UHFFFAOYSA-N |
| InChI | InChI=1S/C18H28N6OP.F6P/c1-2-10-18-17(9-1)19-20-24(18)25-26(21-11-3-4-12-21,22-13-5-6-14-22)23-15-7-8-16-23;1-7(2,3,4,5)6/h1-2,9-10H,3-8,11-16H2;/q+1;-1 |
| PubChem CID | 2724699 |
| UN Number | UN3077 |
| REACH Code | Y110 |
| HTS Code | 2933.99.8290 |
| Tariff Code | 2933998090 |
Safety & GHS
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Health Hazard
GHS07
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Hazardous to the Environment
GHS09
Hazard statements
- H302 Harmful if swallowed
- H315 Causes skin irritation
- H317 May cause an allergic skin reaction
- H319 Causes serious eye irritation
- H335 May cause respiratory irritation
- H410 Very toxic to aquatic life with long lasting effects
Precautionary statements
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray
- P273 Avoid release to the environment
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P302+P352 IF ON SKIN: Wash with soap and water
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
- P308+P313 IF exposed or concerned: Get medical advice/attention
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Portuguese, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- (Benzotriazol-1-yloxy)tripyrrolidinophosphonium hexafluorophosphate
- 1-Benzotriazolyloxytripyrrolidinylphosphonium hexafluorophosphate
- 1H-Benzotriazol-1-yloxytripyrrolidinophosphonium Hexafluorophosphate
- benzotriazol-1-yl-oxytripyrrolidinphosphonium hexafluorophosphate
- benzotriazol-1-yloxy(tripyrrolidin-1-yl)phosphanium;hexafluorophosphate
- benzotriazol-1-yloxy(tripyrrolidin-1-yl)phosphonium hexafluorophosphate
- Benzotriazole-1-yl-
- Benzotriazole-1-yl-oxytripyrrolidinophosphonium hexafluorophosphate
- bopp
- PyBOP
Frequently asked questions
What is Benzotriazole-1-yl-oxy-tris-pyrrolidino-phosphonium hexafluorophosphate (PyBOP) commonly used for?
PyBOP is primarily used as a coupling reagent in peptide synthesis, enabling efficient amide bond formation under mild conditions.
What is the chemical formula and molecular weight of PyBOP?
The formula is C₁₈H₂₈N₆OP·PF₆, and the molecular weight is 520.39 g/mol.
What is the hazard classification (signal word) for PyBOP?
The signal word is Warning, indicating it poses moderate hazards requiring careful handling.
How should PyBOP be stored?
Store PyBOP at ambient temperature in a dry, well-ventilated area, away from moisture and incompatible substances.
Does Molekula supply PyBOP in bulk quantities?
Yes, Molekula can provide PyBOP in bulk, with quantities tailored to your research or production needs—contact us for pricing and availability.
What documentation comes with a PyBOP order?
Each order includes a Certificate of Analysis (CoA), Material Safety Data Sheet (MSDS), and batch-specific documentation for traceability.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.