Molekula
Aminopterin hydrate
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Aminopterin hydrate is a folate antagonist and antimetabolite primarily used in research for its cytotoxic effects, particularly in studying cancer and autoimmune diseases. It inhibits dihydrofolate reductase, disrupting DNA synthesis. Beyond laboratory work as a folic acid antagonist, it has documented use as a rodenticide in agricultural pest control. This chemical has a CAS number of 54-62-6, a molecular formula of C19H20N8O5, and a molecular weight of 440.41. It must be stored at -15 to -20°C and carries a "Danger" signal word due to its high toxicity. Molekula supplies Aminopterin hydrate from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.
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25 mg — $144.70 per pack
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100 mg — $293.20 per pack
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | Brownish yellow or yellow crystalline powder |
| Water | ≤2.0% |
| Identification | Conforms to reference |
| Chromatographic purity | Total ≤2.0% |
| Assay | ≥98% |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | -15 to -20 °C |
| Transport Class | 6.1 |
| Packing Group | I |
| Acidity | Neutral |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Appearance | Orange-yellow powder |
| pKa | pKa = 5.5 |
| log P (octanol/water) | -1.8 |
Source: PubChem CID 169371 (HSDB, DrugBank)
Identification
| Property | Value |
|---|---|
| SKU | 38080224 |
| CAS Number | 54-62-6 |
| IUPAC Name | (2S)-2-[[4-[(2,4-diaminopteridin-6-yl)methylamino]benzoyl]amino]pentanedioic acid |
| EC Number | 200-209-9 |
| Molecular Formula | C19H20N8O5 |
| Molecular Weight | 440.41 |
| Exact Mass | 440.1557 |
| SMILES | C1=CC(=CC=C1C(=O)N[C@@H](CCC(=O)O)C(=O)O)NCC2=CN=C3C(=N2)C(=NC(=N3)N)N |
| InChIKey | TVZGACDUOSZQKY-LBPRGKRZSA-N |
| InChI | InChI=1S/C19H20N8O5/c20-15-14-16(27-19(21)26-15)23-8-11(24-14)7-22-10-3-1-9(2-4-10)17(30)25-12(18(31)32)5-6-13(28)29/h1-4,8,12,22H,5-7H2,(H,25,30)(H,28,29)(H,31,32)(H4,20,21,23,26,27)/t12-/m0/s1 |
| PubChem CID | 169371 |
| UN Number | UN2811 |
| REACH Code | Y110 |
| TSCA Listed | Yes |
| HTS Code | 29335995 |
| Tariff Code | 2933599590 |
Safety & GHS
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Toxic
GHS06
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Serious Health Hazard
GHS08
Hazard statements
- H300 Fatal if swallowed
- H340 May cause genetic defects
- H351 Suspected of causing cancer
- H360 May damage fertility or the unborn child
Precautionary statements
- P201 Obtain special instructions before use
- P260 Do not breathe dust/fume/gas/mist/vapours/spray
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician
- P308+313 IF exposed or concerned: Get medical advice/attention
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- 4-Amino-PGA
- 4-Aminofolic acid
- 4-Aminopteroylglutamic acid
- A-Ninopterin
- Aminopteridine
- aminopterin
- Aminopterine
- Aminopterinum
- Aminotrexate
- APGA
Frequently asked questions
What is aminopterin hydrate used for?
Aminopterin hydrate is primarily used in research as a folate antagonist to study cell growth inhibition, cancer biology, and metabolic pathways.
What is the chemical formula and molecular weight of aminopterin hydrate?
The chemical formula is **C19H20N8O5**, and the molecular weight is **440.41 g/mol**.
How should aminopterin hydrate be stored?
Store at **-15 to -20°C** to maintain stability and potency.
What grade of aminopterin hydrate does Molekula supply?
Molekula supplies **research-grade aminopterin hydrate**, suitable for laboratory and experimental use.
Can Molekula supply aminopterin hydrate in bulk quantities?
Yes, bulk quantities are available upon request—please contact our sales team for pricing and lead times.
What documentation comes with an order of aminopterin hydrate?
Each order includes a **Certificate of Analysis (CoA)**, **Material Safety Data Sheet (MSDS)**, and **batch-specific documentation** for traceability.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.