Molekula
Actinomycin D
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Actinomycin D is a potent antibiotic and chemotherapy agent used primarily in research and medical treatments for certain cancers, such as Wilms’ tumor and testicular cancer. It works by inhibiting DNA transcription, making it valuable in both therapeutic and laboratory applications. This chemical has a CAS number of 50-76-0, with the molecular formula C62H86N12O16 and a molecular weight of 1255.42. It must be stored between 2 to 8°C and carries a **Danger** signal word due to its high toxicity. Molekula supplies Actinomycin D from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.
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2 mg — £59.80 per pack ex VAT · £71.76 inc. VAT
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5 mg — £73.50 per pack ex VAT · £88.20 inc. VAT
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25 mg — £159.90 per pack ex VAT · £191.88 inc. VAT
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | Orange red powder |
| Specific rotation | -292° - -317° |
| Purity (HPLC) | ≥95% |
| Identification | Ultraviolet absorption Ratio: A240/A44s between 1.30 to1.50 |
| Loss on Drying | ≤5.0% |
| Solubility | Soluble in acetone, ethyl acetate |
| Total Impurities | ≤5.0% |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | 2 to 8 °C |
| Transport Class | 6.1 |
| Packing Group | II |
| Acidity | Neutral |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Appearance | Bright red crystalline powder |
| Melting Point | 241.5 - 243 °C |
| Water Solubility | 40 g/L at 10 °C |
| pKa | pKa = 11.90 |
| log P (octanol/water) | 3.21 |
Source: PubChem CID 457193 (HSDB, Human Metabolome Database (HMDB))
Identification
| Property | Value |
|---|---|
| SKU | 32117981 |
| CAS Number | 50-76-0 |
| IUPAC Name | 2-amino-4,6-dimethyl-3-oxo-1-N,9-N-bis[(3R,6S,7R,10S,16S)-7,11,14-trimethyl-2,5,9,12,15-pentaoxo-3,10-di(propan-2-yl)-8-oxa-1,4,11,14-tetrazabicyclo[14.3.0]nonadecan-6-yl]phenoxazine-1,9-dicarboxamide |
| EC Number | 200-063-6 |
| Molecular Formula | C62H86N12O16 |
| Molecular Weight | 1255.42 |
| Exact Mass | 1254.6285 |
| SMILES | C[C@@H]1[C@@H](C(=O)N[C@@H](C(=O)N2CCC[C@H]2C(=O)N(CC(=O)N([C@H](C(=O)O1)C(C)C)C)C)C(C)C)NC(=O)C3=C4C(=C(C=C3)C)OC5=C(C(=O)C(=C(C5=N4)C(=O)N[C@H]6[C@H](OC(=O)[C@@H](N(C(=O)CN(C(=O)[C@@H]7CCCN7C(=O)[C@H](NC6=O)C(C)C)C)C)C(C)C)C)N)C |
| InChIKey | RJURFGZVJUQBHK-IIXSONLDSA-N |
| InChI | InChI=1S/C62H86N12O16/c1-27(2)42-59(84)73-23-17-19-36(73)57(82)69(13)25-38(75)71(15)48(29(5)6)61(86)88-33(11)44(55(80)65-42)67-53(78)35-22-21-31(9)51-46(35)64-47-40(41(63)50(77)32(10)52(47)90-51)54(79)68-45-34(12)89-62(87)49(30(7)8)72(16)39(76)26-70(14)58(83)37-20-18-24-74(37)60(85)43(28(3)4)66-56(45)81/h21-22,27-30,33-34,36-37,42-45,48-49H,17-20,23-26,63H2,1-16H3,(H,65,80)(H,66,81)(H,67,78)(H,68,79)/t33-,34-,36+,37+,42-,43-,44+,45+,48+,49+/m1/s1 |
| PubChem CID | 457193 |
| UN Number | UN3462 |
| REACH Code | Y110 |
| HTS Code | 29419010 |
| Tariff Code | 2941900000 |
Safety & GHS
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Toxic
GHS06
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Serious Health Hazard
GHS08
Hazard statements
- H300 Fatal if swallowed
- H341 Suspected of causing genetic defects
- H350 May cause cancer
- H360FD May damage fertility. May damage the unborn child.
Precautionary statements
- P201 Obtain special instructions before use
- P263 Avoid contact during pregnancy/while nursing
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician
- P302+352 IF ON SKIN: Wash with soap and water
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
- P308+313 IF exposed or concerned: Get medical advice/attention
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- Actinomycin C1
- Actinomycin I1
- Actinomycin IV
- Actinomycin X1
- Cosmegen
- Dactinomicina
- DACTINOMYCIN
- Dactinomycine
- Meractinomycin
- Oncostatin K
Frequently asked questions
What is Actinomycin D used for?
Actinomycin D is primarily used as an antibiotic and anticancer agent, particularly in research for studying DNA transcription and as a therapeutic in certain cancers.
What is the chemical formula and molecular weight of Actinomycin D?
The chemical formula is **C62H86N12O16**, and the molecular weight is **1255.42 g/mol**.
How should Actinomycin D be stored?
Store Actinomycin D at **2 to 8°C** to maintain stability and potency.
What grades or purities of Actinomycin D does Molekula supply?
Molekula supplies Actinomycin D in **research-grade purity**, typically ≥95% by HPLC, suitable for laboratory applications.
Can Molekula supply Actinomycin D in bulk quantities?
Yes, Molekula can provide Actinomycin D in bulk, subject to availability and regulatory compliance for large-scale orders.
What documentation comes with an order of Actinomycin D?
Each order includes a **Certificate of Analysis (CoA)**, **Material Safety Data Sheet (MSDS)**, and a **batch-specific documentation** for traceability.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.