Molekula
5'-O-(4,4'-Dimethoxytrityl)thymidine (DMT-T)
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
5'-O-(4,4'-Dimethoxytrityl)thymidine (DMT-T) is a protected nucleoside widely used in oligonucleotide synthesis as a key building block for DNA sequences. It features a 4,4'-dimethoxytrityl (DMT) protecting group at the 5' hydroxyl, enabling controlled chain elongation during phosphoramidite chemistry. This chemical has a CAS number of 40615-39-2, molecular formula C31H32N2O7, and a molecular weight of 544.59 g/mol. Store at 2–8°C under inert conditions to preserve stability. The product carries a **Warning** signal word due to potential skin/eye irritation. Molekula supplies 5'-O-(4,4'-Dimethoxytrityl)thymidine from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.
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1 g — £46.50 per pack ex VAT · £55.80 inc. VAT
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Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
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Specifications
| Property | Value |
|---|---|
| Appearance | Solid |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | 2 to 8 °C |
| Acidity | Neutral |
Identification
| Property | Value |
|---|---|
| SKU | 18093653 |
| CAS Number | 40615-39-2 |
| IUPAC Name | 1-[(2R,4S,5R)-5-[[bis(4-methoxyphenyl)-phenylmethoxy]methyl]-4-hydroxyoxolan-2-yl]-5-methylpyrimidine-2,4-dione |
| EC Number | 255-003-1 |
| Molecular Formula | C31H32N2O7 |
| Molecular Weight | 544.59 |
| Exact Mass | 544.221 |
| SMILES | CC1=CN(C(=O)NC1=O)[C@H]2C[C@@H]([C@H](O2)COC(C3=CC=CC=C3)(C4=CC=C(C=C4)OC)C5=CC=C(C=C5)OC)O |
| InChIKey | UBTJZUKVKGZHAD-UPRLRBBYSA-N |
| InChI | InChI=1S/C31H32N2O7/c1-20-18-33(30(36)32-29(20)35)28-17-26(34)27(40-28)19-39-31(21-7-5-4-6-8-21,22-9-13-24(37-2)14-10-22)23-11-15-25(38-3)16-12-23/h4-16,18,26-28,34H,17,19H2,1-3H3,(H,32,35,36)/t26-,27+,28+/m0/s1 |
| PubChem CID | 162419 |
| REACH Code | Y110 |
| HTS Code | 29349990 |
| Tariff Code | 2934999090 |
Safety & GHS
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Health Hazard
GHS07
Hazard statements
- H315 Causes skin irritation
- H319 Causes serious eye irritation
- H335 May cause respiratory irritation
Precautionary statements
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P302+352 IF ON SKIN: Wash with soap and water
- P304+340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
- P308+313 IF exposed or concerned: Get medical advice/attention
Documents
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- 5-DMTT
- 5'--O--(4,4'-dimethyoxytrityl) thymidine
- 5'-O-(4,4'-Dimethoxytrityl)thymidine
- 5'-O-Dimethoxytrityl-deoxythymidine
- 5'-O-Dimethoxytritylthymidine
- 5'-O-Dimethyltritylthymidine
- 5'-O-DMT-dT
- 5'-O-DMT-Thymidine
- DMT-T
- Thymidine, 5'-O-[bis(4-methoxyphenyl)phenylmethyl]-
Frequently asked questions
What is 5'-O-(4,4'-Dimethoxytrityl)thymidine (DMT-T) used for?
DMT-T is primarily used in oligonucleotide synthesis as a protected thymidine nucleoside, enabling controlled chain elongation in DNA/RNA synthesis.
What is the chemical formula and molecular weight of DMT-T?
The chemical formula is **C₃₁H₃₂N₂O₇**, and the molecular weight is **544.59 g/mol**.
How should DMT-T be stored?
Store DMT-T at **2–8°C** in a dry, inert atmosphere to prevent degradation from moisture or light.
What grade or purity is available for DMT-T?
Molekula supplies **synthesis-grade DMT-T**, typically ≥98% purity by HPLC, suitable for oligonucleotide manufacturing.
Can Molekula supply DMT-T in bulk quantities?
Yes, we offer DMT-T in bulk (1g–1kg+), with custom packaging available upon request for large-scale synthesis.
What documentation is provided with a DMT-T order?
Each order includes a **Certificate of Analysis (CoA)**, Safety Data Sheet (SDS), and batch-specific quality documentation.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.