Molekula
5-Fluorouracil USP
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
5-Fluorouracil USP is a synthetic fluorinated pyrimidine analog used primarily as a chemotherapy agent to treat cancers, including colorectal, breast, and stomach cancers. It interferes with DNA and RNA synthesis, inhibiting tumor growth. This pharmaceutical-grade chemical has a CAS number of 51-21-8, a molecular formula of C4H3FN2O2, and a molecular weight of 130.08 g/mol. It is stable at ambient storage conditions but requires careful handling due to its hazardous nature, marked by a "Danger" signal word. Molekula supplies 5-Fluorouracil USP from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
Pack sizes & pricing
Pricing on request — packs available from research to bulk quantities.
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Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White to off-white powder |
| Loss on Drying | <0.5% |
| Assay | 99% min |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Transport Class | 6.1 |
| Packing Group | III |
| Acidity | Acid |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Appearance | White to practically white crystalline powder |
| Odour | Practically odorless |
| Melting Point | 282 °C (decomposes) |
| Boiling Point | 361 °C at 760 mmHg |
| Water Solubility | 11.1 g/L at 22 °C |
| Solubility (other solvents) | Soluble in methanol-water mixtures |
| Vapour Pressure | 0.00001 mmHg at 25 °C |
| pKa | pKa = 8.02 |
| log P (octanol/water) | -0.89 |
Source: PubChem CID 3385 (HSDB, PAC Chemical Database, DrugBank)
Identification
| Property | Value |
|---|---|
| SKU | 90029462 |
| CAS Number | 51-21-8 |
| IUPAC Name | 5-fluoro-1H-pyrimidine-2,4-dione |
| EC Number | 200-085-6 |
| Molecular Formula | C4H3FN2O2 |
| Molecular Weight | 130.08 |
| Exact Mass | 130.0179 |
| SMILES | C1=C(C(=O)NC(=O)N1)F |
| InChIKey | GHASVSINZRGABV-UHFFFAOYSA-N |
| InChI | InChI=1S/C4H3FN2O2/c5-2-1-6-4(9)7-3(2)8/h1H,(H2,6,7,8,9) |
| PubChem CID | 3385 |
| UN Number | UN2811 |
| REACH Code | Y110 |
| TSCA Listed | Yes |
| Tariff Code | 2933599590 |
Safety & GHS
-
Toxic
GHS06
-
Serious Health Hazard
GHS08
Hazard statements
- H301 Toxic if swallowed
- H312 Harmful in contact with skin
- H340 May cause genetic defects
- H351 Suspected of causing cancer
- H360FD May damage fertility. May damage the unborn child.
- H372 Causes damage to organs through prolonged or repeated exposure
Precautionary statements
- P260 Do not breathe dust/fume/gas/mist/vapours/spray
- P263 Avoid contact during pregnancy/while nursing
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician
- P302+352 IF ON SKIN: Wash with soap and water
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
- P308+313 IF exposed or concerned: Get medical advice/attention
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Portuguese, Russian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- 5-Fluorouracil
- Arumel
- Carzonal
- Efudex
- Fluoroblastin
- fluorouracil
- Fluracil
- Fluril
- Phthoruracil
- Queroplex
Frequently asked questions
What is 5-Fluorouracil USP primarily used for?
5-Fluorouracil USP is primarily used as a chemotherapeutic agent in the treatment of cancers, including colorectal, breast, and stomach cancers, as well as topical treatment for actinic keratosis.
What is the chemical formula and molecular weight of 5-Fluorouracil?
The chemical formula is **C₄H₃FN₂O₂** and the molecular weight is **130.08 g/mol**.
How should 5-Fluorouracil USP be stored?
Store at **ambient temperature**, away from moisture and direct sunlight, in a tightly sealed container.
What grade of 5-Fluorouracil does Molekula supply?
Molekula supplies **USP-grade 5-Fluorouracil**, meeting United States Pharmacopeia standards for pharmaceutical applications.
Can Molekula supply 5-Fluorouracil USP in bulk quantities?
Yes, Molekula can provide **bulk quantities** of 5-Fluorouracil USP, subject to regulatory compliance and customer requirements.
What documentation comes with an order of 5-Fluorouracil USP?
Each order includes a **Certificate of Analysis (CoA)**, **Material Safety Data Sheet (MSDS)**, and **USP compliance documentation**.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.