Molekula
5-Ethylthio-1(H)-tetrazole
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
5-Ethylthio-1(H)-tetrazole (ETT) is a heterocyclic organic compound primarily used as an activator for phosphoramidite coupling in solid-phase oligonucleotide (DNA and RNA) synthesis, where it is commonly supplied as a 0.25 M solution in acetonitrile. It features a tetrazole ring with an ethylthio substituent, enabling versatile reactivity in organic transformations. This chemical has a CAS number of 89797-68-2, a molecular formula of C3H6N4S (or CN4(H)SCH2CH3), and a molecular weight of 130.17 g/mol. It should be stored between 2 to 8°C and is classified with a signal word of Warning. Molekula supplies 5-Ethylthio-1(H)-tetrazole from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
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25 g — £52.60 per pack ex VAT · £63.12 inc. VAT
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Specifications
| Property | Value |
|---|---|
| Appearance | White to off-white powder |
| Melting Point | 85 - 89°C |
| Water | ≤ 0.03% |
| Purity (HPLC) | ≥ 99.0% |
| Solubility | Clear, Colourless |
| TLC | One spot |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | 2 to 8 °C |
| Transport Class | 4.1 (8) |
| Packing Group | II |
| Acidity | Base |
Identification
| Property | Value |
|---|---|
| SKU | 51057635 |
| CAS Number | 89797-68-2 |
| IUPAC Name | 5-ethylsulfanyl-2H-tetrazole |
| Molecular Formula | CN4(H)SCH2CH3 |
| Molecular Weight | 130.17 |
| Exact Mass | 130.0313 |
| SMILES | CCSC1=NNN=N1 |
| InChIKey | GONFBOIJNUKKST-UHFFFAOYSA-N |
| InChI | InChI=1S/C3H6N4S/c1-2-8-3-4-6-7-5-3/h2H2,1H3,(H,4,5,6,7) |
| PubChem CID | 2758928 |
| UN Number | UN2925 |
| REACH Code | Y110 |
| HTS Code | 29339979 |
| Tariff Code | 2933998090 |
Safety & GHS
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Flammable
GHS02
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Corrosive
GHS05
Hazard statements
- EUH044 Risk of explosion if heated under confinement
- H228 Flammable solid
- H314 (sub cat. 1B) Causes severe skin burns and eye damage
- H335 May cause respiratory irritation
Precautionary statements
- P202 Do not handle until all safety precautions have been read and understood
- P210 Keep away from heat/sparks/open flames/hot surfaces - No smoking
- P260 Do not breathe dust/fume/gas/mist/vapours/spray
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician
- P303+361 IF ON SKIN (or hair): Remove immediately all contaminated clothing. Rinse with water/shower
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
Documents
Safety Data Sheets (SDS)
Available in English, English (US), French, German, Italian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- 5-(ethylsulfanyl)-1H-1,2,3,4-tetrazole
- 5-(Ethylsulfanyl)-1H-tetrazole
- 5-(ethylsulfanyl)-2H-1,2,3,4-tetrazole
- 5-(Ethylsulfanyl)-2H-tetrazolato
- 5-ethylsulfanyl-2H-tetrazole
- 5-Ethylthiotetrazole
- ETT Activator, 0.25 M
- ETT Activator, 0.25 M in acetonitrile
- ETT Activator, 0.3M
- ETT Activator, 0.50 M in acetonitrile
Frequently asked questions
What is 5-Ethylthio-1(H)-tetrazole commonly used for?
5-Ethylthio-1(H)-tetrazole is primarily used as an activator for phosphoramidite coupling in oligonucleotide (DNA and RNA) synthesis, and as a building block for other heterocyclic compounds.
What is the chemical formula and molecular weight of 5-Ethylthio-1(H)-tetrazole?
The chemical formula is CN₄(H)SCH₂CH₃ (C₃H₆N₄S), and the molecular weight is 130.17 g/mol.
How should 5-Ethylthio-1(H)-tetrazole be stored?
Store at 2–8°C in a cool, dry place, away from incompatible substances. Follow proper chemical storage protocols for hazardous materials.
What purity grades are available for this compound?
Molekula supplies reagent-grade 5-Ethylthio-1(H)-tetrazole, typically ≥97% purity. Custom specifications may be available upon request.
Can Molekula supply 5-Ethylthio-1(H)-tetrazole in bulk quantities?
Yes, bulk quantities are available upon inquiry. Minimum order quantities and packaging options vary based on customer needs.
What documentation comes with an order of 5-Ethylthio-1(H)-tetrazole?
Each order includes a Certificate of Analysis (CoA), Material Safety Data Sheet (MSDS), and a product specification sheet. Additional documentation may be provided upon request.
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