Molekula
3-Hydroxy-3-methylglutaric acid
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
3-Hydroxy-3-methylglutaric acid is an organic acid with a branched structure, commonly used as an intermediate in pharmaceutical synthesis, metabolic research, and as a building block for polymer chemistry. It appears as a white crystalline solid with applications in studying metabolic pathways and developing drugs targeting fatty acid oxidation disorders. CAS 503-49-1, molecular formula HOC(CH3)(CH2CO2H)2, molecular weight 162.14 g/mol, and requires storage between 2–8°C. The product carries a warning signal word due to potential irritant properties. Molekula supplies 3-Hydroxy-3-methylglutaric acid from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
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100 mg — $260.00 per pack
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Specifications
| Property | Value |
|---|---|
| Appearance | White to Off-White Powder |
| Water | ≤ 5 % |
| Purity | ≥ 95.0 % |
| Identification (IR) | Conforms to Structure |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | 2 to 8 °C |
| Acidity | Acid |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Melting Point | 105 °C |
Source: PubChem CID 1662 (Human Metabolome Database (HMDB))
Identification
| Property | Value |
|---|---|
| SKU | 90034038 |
| CAS Number | 503-49-1 |
| IUPAC Name | 3-hydroxy-3-methylpentanedioic acid |
| EC Number | 207-971-1 |
| Molecular Formula | HOC(CH3)(CH2CO2H)2 |
| Molecular Weight | 162.14 |
| Exact Mass | 162.0528 |
| SMILES | CC(CC(=O)O)(CC(=O)O)O |
| InChIKey | NPOAOTPXWNWTSH-UHFFFAOYSA-N |
| InChI | InChI=1S/C6H10O5/c1-6(11,2-4(7)8)3-5(9)10/h11H,2-3H2,1H3,(H,7,8)(H,9,10) |
| PubChem CID | 1662 |
| REACH Code | Y113 |
| HTS Code | 29182975 |
| Tariff Code | 2918199890 |
Safety & GHS
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Health Hazard
GHS07
Hazard statements
- H315 Causes skin irritation
- H319 Causes serious eye irritation
Precautionary statements
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P302+352 IF ON SKIN: Wash with soap and water
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
- P333+313 IF skin irritation or a rash occurs: Get medical advice/attention
- P337+313 If eye irritation persists get medical advice/attention
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- 3-Hydorxy-3-methylglutaric acid
- 3-Hydroxy-3-methylglutarate
- 3-Hydroxy-3-methylpentanedioic acid
- beta-Hydroxy-beta-methylglutaric acid
- CB 337
- Dicrotalic acid
- HMGA
- MEGLUTOL
- Meglutolum
- Pentanedioic acid, 3-hydroxy-3-methyl-
Frequently asked questions
What is 3-Hydroxy-3-methylglutaric acid commonly used for?
It is primarily used as an intermediate in pharmaceutical synthesis and in metabolic and lipid research, where it (as meglutol) is studied as a weak HMG-CoA reductase inhibitor and anticholesteremic agent and serves as a urinary marker of HMG-CoA lyase deficiency, and as a building block in organic chemistry for custom chemical manufacturing.
What is the molecular formula and molecular weight of 3-Hydroxy-3-methylglutaric acid?
The molecular formula is HOC(CH₃)(CH₂CO₂H)₂, and the molecular weight is 162.14 g/mol.
How should 3-Hydroxy-3-methylglutaric acid be stored?
Store at 2 to 8°C in a cool, dry place, away from direct sunlight and incompatible substances. Follow proper laboratory or industrial storage protocols.
What purity grades or forms (e.g., powder, liquid) does Molekula offer for this product?
We supply pharmaceutical-grade and research-grade 3-Hydroxy-3-methylglutaric acid, typically as a white crystalline powder with ≥98% purity. Bulk customization may be available upon request.
Can Molekula supply this product in bulk quantities?
Yes, we offer bulk quantities (minimum order quantities vary by grade) and can accommodate large-scale orders for industrial or pharmaceutical applications. Contact our sales team for pricing and logistics details.
What documentation comes with an order of 3-Hydroxy-3-methylglutaric acid?
Each order includes a Certificate of Analysis (CoA), Material Safety Data Sheet (MSDS), and batch-specific documentation for traceability. Additional compliance certificates (e.g., GMP, REACH) may be provided for pharmaceutical or regulated industries.
Ready to order or need a custom pack?
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