Molekula
2-Nitrobenzenesulfonyl chloride
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
2-Nitrobenzenesulfonyl chloride is a highly reactive sulfonyl chloride derivative used primarily as a reagent in organic synthesis, particularly for the preparation of sulfonamides, sulfonyl fluorides, and other sulfonyl-containing compounds. It serves as an electrophile in substitution and coupling reactions, enabling the introduction of sulfonyl groups into target molecules. This chemical has a CAS number of 1694-92-4, with a molecular formula of C6H4ClNO4S and a molecular weight of 221.62 g/mol. It is classified under the Danger signal word due to its corrosive properties: it may be corrosive to metals and causes severe skin burns and eye damage, requiring careful handling. Store at ambient conditions in a dry, well-ventilated area, protected from moisture and heat. Molekula supplies 2-Nitrobenzenesulfonyl chloride from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
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100 g — $112.40 per pack
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Specifications
| Property | Value |
|---|---|
| Appearance | Light yellow crystalline powder |
| Melting Point | 64 - 67 Deg C |
| Water | 1% max |
| Purity | 98% min |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Transport Class | 8 |
| Packing Group | II |
| Acidity | Acid |
Identification
| Property | Value |
|---|---|
| SKU | 20282634 |
| CAS Number | 1694-92-4 |
| IUPAC Name | 2-nitrobenzenesulfonyl chloride |
| EC Number | 216-907-1 |
| Molecular Formula | C6H4ClNO4S |
| Molecular Weight | 221.62 |
| Exact Mass | 220.955 |
| SMILES | C1=CC=C(C(=C1)[N+](=O)[O-])S(=O)(=O)Cl |
| InChIKey | WPHUUIODWRNJLO-UHFFFAOYSA-N |
| InChI | InChI=1S/C6H4ClNO4S/c7-13(11,12)6-4-2-1-3-5(6)8(9)10/h1-4H |
| PubChem CID | 15540 |
| UN Number | UN3261 |
| REACH Code | Y110 |
| TSCA Listed | Yes |
| HTS Code | 2904.99.4700 |
| Tariff Code | 2904990090 |
Safety & GHS
-
Corrosive
GHS05
Hazard statements
- H290 May be corrosive to metals
- H314 (sub cat. 1B) Causes severe skin burns and eye damage
Precautionary statements
- P260 Do not breathe dust/fume/gas/mist/vapours/spray
- P264 Wash thoroughly after handling
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+P330+P331 IF SWALLOWED: Rinse mouth. Do NOT induce vomiting
- P304+P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing
- P305+P351+P338 IF IN EYES: Rinse continuously with water for several minutes. Remove contact lenses if present and easy to do, continue rinsing
Documents
Safety Data Sheets (SDS)
Available in English, German, Spanish, French, Italian, Portuguese, Arabic, Dutch.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- 2-nitrobenzene-1-sulfonyl chloride
- 2-Nitrobenzenesulphonyl chloride
- 2-nitrophenylsulfonyl chloride
- Benzenesulfonyl chloride, 2-nitro-
- Benzenesulfonyl chloride, nitro-
- Benzenesulfonyl chloride, o-nitro-
- chloro(2-nitrophenyl)sulfone
- o-Nitrobenzenesulfonyl chloride
- o-Nitrophenylsulfonyl chloride
- o-Ns-Cl
Frequently asked questions
What is 2-Nitrobenzenesulfonyl chloride commonly used for?
It is primarily used as a reagent in organic synthesis, particularly for the preparation of sulfonamides (for example, 2-nitrobenzenesulfonyl (nosyl) protection of amines, as in the Fukuyama amine synthesis), sulfonate esters, and other sulfonyl derivatives.
What is the molecular formula and molecular weight of 2-Nitrobenzenesulfonyl chloride?
The molecular formula is C₆H₄ClNO₄S, and the molecular weight is 221.62 g/mol.
How should 2-Nitrobenzenesulfonyl chloride be stored?
Store in a tightly sealed container at ambient temperature, away from moisture and incompatible materials.
What grade or purity is available for this product?
Molekula supplies this product in technical/industrial grade purity, suitable for most synthetic applications.
Can Molekula supply 2-Nitrobenzenesulfonyl chloride in bulk quantities?
Yes, we offer bulk quantities upon request, with flexible packaging options for large orders.
What documentation is provided with an order of this product?
Each order includes a Certificate of Analysis (CoA), Material Safety Data Sheet (MSDS), and a product specification sheet.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.