Molekula
2-Amino-6-purinethiol (6-Thioguanine)
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
2-Amino-6-purinethiol, also known as 6-thioguanine, is a purine analog used in the treatment of certain cancers and autoimmune disorders. In the laboratory it is a selective agent in mutagen screening, where resistance marks mutant mammalian cells, and it is the active ingredient in the leukaemia medicines Lanvis and Tabloid. It functions as an antimetabolite by interfering with DNA synthesis. Available in powder form with a molecular weight of 167.19 g/mol, its CAS number is 154-42-7, and it has a molecular formula of C5H5N5S. Store at ambient temperature. Signal word: Danger. Molekula supplies 2-Amino-6-purinethiol (6-Thioguanine) from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
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1 g — $58.70 per pack
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Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | Light yellow powder |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Transport Class | 6.1 |
| Packing Group | III |
| Acidity | Base |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Appearance | Yellow, crystalline powder |
| Odour | Odorless or practically odorless |
| Solubility (other solvents) | Readily soluble in dilute aqueous alkali. Insoluble in water, alcohol, or chloroform |
| log P (octanol/water) | -0.07 |
Source: PubChem CID 2723601 (HSDB, NCI Investigational Drugs)
Identification
| Property | Value |
|---|---|
| SKU | 66238710 |
| CAS Number | 154-42-7 |
| IUPAC Name | 2-amino-3,7-dihydropurine-6-thione |
| EC Number | 205-827-2 |
| Molecular Formula | C5H5N5S |
| Molecular Weight | 167.19 |
| Exact Mass | 167.0266 |
| SMILES | C1=NC2=C(N1)C(=S)N=C(N2)N |
| InChIKey | WYWHKKSPHMUBEB-UHFFFAOYSA-N |
| InChI | InChI=1S/C5H5N5S/c6-5-9-3-2(4(11)10-5)7-1-8-3/h1H,(H4,6,7,8,9,10,11) |
| PubChem CID | 2723601 |
| UN Number | UN2811 |
| REACH Code | Y110 |
| HTS Code | 29335995 |
| Tariff Code | 2933599590 |
Safety & GHS
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Toxic
GHS06
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Serious Health Hazard
GHS08
Hazard statements
- H301 Toxic if swallowed
- H341 Suspected of causing genetic defects
Precautionary statements
- P260 Do not breathe dust/fume/gas/mist/vapours/spray
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- 2-Amino 6MP
- 2-Amino-6-mercaptopurine
- 2-Amino-6-purinethiol
- 6-Mercaptoguanine
- 6-Thioguanine
- Lanvis
- Tabloid
- thioguanine
- Tioguanin
- Tioguanine
Frequently asked questions
What is 2-Amino-6-purinethiol (6-Thioguanine) used for?
It is itself an antineoplastic antimetabolite drug (marketed as Lanvis and Tabloid) used in the treatment of leukaemia, particularly acute myeloid leukaemia; it is incorporated into DNA and inhibits DNA synthesis. In research it is used as a bioactive small molecule and analytical reference reagent.
What is the chemical formula and molecular weight of 2-Amino-6-purinethiol?
The formula is C5H5N5S with a molecular weight of 167.19 g/mol.
How should 2-Amino-6-purinethiol be stored?
It should be stored at ambient temperature, protected from light and moisture.
What grade is available for 2-Amino-6-purinethiol?
Available in research grade; custom grades may be available upon request.
Can Molekula supply 2-Amino-6-purinethiol in bulk?
Yes, bulk quantities are available—please contact our sales team for pricing and availability.
What documentation comes with an order of 2-Amino-6-purinethiol?
Each order includes a Certificate of Analysis (CoA) and Safety Data Sheet (SDS) with the shipment.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.