Molekula
1,4-Dioxa-8-azaspiro[4.5]decane
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
1,4-Dioxa-8-azaspiro[4.5]decane (CAS 177-11-7) is a heterocyclic organic compound used as a building block in pharmaceutical synthesis, particularly for ligands and drug intermediates. Its unique spiro structure enables selective chemical reactivity in medicinal chemistry applications. This compound has a molecular formula of C7H13NO2 and a molecular weight of 143.18 g/mol. It is stable at ambient storage conditions and classified with a signal word of "Warning" under standard hazard communication guidelines. Molekula supplies 1,4-Dioxa-8-azaspiro[4.5]decane from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
Pack sizes & pricing
Pricing on request — packs available from research to bulk quantities.
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Specifications
| Property | Value |
|---|---|
| Appearance | Colourless to yellow liquid |
| FT-IR | Conforms |
| Purity (NMR) | ≥98.0% |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Flash Point | 7 °C |
| Acidity | Neutral |
Identification
| Property | Value |
|---|---|
| SKU | 90038383 |
| CAS Number | 177-11-7 |
| IUPAC Name | 1,4-dioxa-8-azaspiro[4.5]decane |
| EC Number | 205-868-6 |
| Molecular Formula | C7H13NO2 |
| Molecular Weight | 143.18 |
| Exact Mass | 143.0946 |
| SMILES | C1CNCCC12OCCO2 |
| InChIKey | KPKNTUUIEVXMOH-UHFFFAOYSA-N |
| InChI | InChI=1S/C7H13NO2/c1-3-8-4-2-7(1)9-5-6-10-7/h8H,1-6H2 |
| PubChem CID | 67435 |
| REACH Code | Y110 |
| HTS Code | 2934.99.9001 |
| Tariff Code | 2934999090 |
Safety & GHS
-
Health Hazard
GHS07
Hazard statements
- H315 Causes skin irritation
- H319 Causes serious eye irritation
- H335 May cause respiratory irritation
Precautionary statements
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray
- P264 Wash thoroughly after handling
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P302+P352 IF ON SKIN: Wash with soap and water
- P304+P340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing
- P305+P351+P338 IF IN EYES: Rinse continuously with water for several minutes. Remove contact lenses if present and easy to do, continue rinsing
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Portuguese, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- 1,4-diazide-8-nonene
- 1,4-Dioxa-8-azaspiro[4.5]decane
- 4-Piperidinone ethyl ketal
- 4-Piperidinone ethylene acetal
- 4-piperidinone ethyleneketal
- 4-Piperidinone, cyclic 1,2-ethanediyl acetal
- 4-Piperidone ethylene acetal
- 4-Piperidone ethylene ketal
- 4,4-(Ethylenedioxy)piperidine
- 8-Aza-1,4-dioxaspiro[4.5]decane
- piperid-4-one ethylene ketal
- Piperidin-4-one ethylene ketal
- Piperidin-4-one monoethylene ketal
- Piperidone-4-ethyleneketal
Frequently asked questions
What is 1,4-dioxa-8-azaspiro[4.5]decane commonly used for?
This compound is primarily used as a protected secondary-amine building block (4-piperidone ethylene ketal), for example as the amine substrate in metal-catalysed C–N couplings such as Buchwald–Hartwig amination, and as a building block in pharmaceutical synthesis, particularly for targeting GPCRs and other receptors.
What is the molecular formula and molecular weight of this product?
The molecular formula is C₇H₁₃NO₂, and the molecular weight is 143.18 g/mol.
How should 1,4-dioxa-8-azaspiro[4.5]decane be stored?
Store at ambient temperature in a tightly sealed container, away from moisture and strong oxidizing agents.
What purity grades are available for this product?
Molekula supplies this compound in reagent grade (98%+ purity) and can provide higher-purity custom synthesis upon request.
Can Molekula supply this product in bulk quantities?
Yes, we offer bulk packaging options (5 kg, 25 kg, and custom quantities) for this compound—please contact us for pricing and lead times.
What documentation is provided with an order of 1,4-dioxa-8-azaspiro[4.5]decane?
Each order includes a Certificate of Analysis (CoA), Material Safety Data Sheet (MSDS), and batch-specific documentation for traceability.
Ready to order or need a custom pack?
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