Molekula
1-Trimethylsilylimidazole
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
1-Trimethylsilylimidazole is a silylating agent used in organic synthesis and as a GC derivatization reagent to selectively silylate hydroxyl groups in alcohols, phenols and carboxylic acids; it does not react with basic amino groups. It is a colorless to pale yellow liquid, highly reactive, and requires careful handling. CAS: 18156-74-6, Molecular Formula: C6H12N2Si, Molecular Weight: 140.26 g/mol. Store at 2 to 8 °C. Signal word: Danger. Molekula supplies 1-Trimethylsilylimidazole from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
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25 g — $88.40 per pack
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Specifications
| Property | Value |
|---|---|
| Appearance | Colourless to light yellow transparent liquid |
| Purity (GC) | ≥98.0% |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | 2 to 8 °C |
| Flash Point | 6 °C |
| Transport Class | 3 |
| Packing Group | II |
| Acidity | Base |
Identification
| Property | Value |
|---|---|
| SKU | 28682294 |
| CAS Number | 18156-74-6 |
| IUPAC Name | imidazol-1-yl(trimethyl)silane |
| EC Number | 242-040-3 |
| Molecular Formula | C6H12N2Si |
| Molecular Weight | 140.26 |
| Exact Mass | 140.077 |
| SMILES | C[Si](C)(C)N1C=CN=C1 |
| InChIKey | YKFRUJSEPGHZFJ-UHFFFAOYSA-N |
| InChI | InChI=1S/C6H12N2Si/c1-9(2,3)8-5-4-7-6-8/h4-6H,1-3H3 |
| PubChem CID | 28925 |
| UN Number | UN1993 |
| REACH Code | Y110 |
| TSCA Listed | Yes |
| HTS Code | 2933293500 |
| Tariff Code | 2933299090 |
Safety & GHS
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Flammable
GHS02
-
Corrosive
GHS05
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Health Hazard
GHS07
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Serious Health Hazard
GHS08
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Hazardous to the Environment
GHS09
Hazard statements
- H225 Highly flammable liquid and vapour
- H302 Harmful if swallowed
- H314 (sub cat. 1C) Causes severe skin burns and eye damage
- H360D May harm the unborn child
- H400 Very toxic to aquatic life
- H411 Toxic to aquatic life with long lasting effects
Precautionary statements
- P210 Keep away from heat/sparks/open flames/hot surfaces - No smoking
- P240 Ground/bond container and receiving equipment
- P241 Use explosion-proof electrical/ventilating/lighting equipment
- P302+352 IF ON SKIN: Wash with soap and water
- P304+340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- (Trimethylsilyl)imidazole
- 1-(Trimethylsilyl)-1H-imidazole
- 1H-Imidazole, 1-(trimethylsilyl)-
- imidazol-1-yl(trimethyl)silane
- Imidazole, 1-(trimethylsilyl)-
- IMIDAZOLE, N-(TRIMETHYLSILYL)-
- N-(Trimethylsilyl)imidazole
- N-trimethylsilylimidizole
- tmsim
- TSIM
Frequently asked questions
What is 1-Trimethylsilylimidazole used for?
It is primarily used as a hydroxyl-selective silylating agent, particularly for silylating alcohols, phenols and carboxylic acids in the presence of amines (with which it does not react), notably as a derivatization reagent for gas chromatography/mass spectrometry, and as a catalyst in various reactions.
What is the chemical formula and molecular weight?
The formula is C6H12N2Si with a molecular weight of 140.26 g/mol.
How should 1-Trimethylsilylimidazole be stored?
It should be stored at 2 to 8 °C, protected from moisture and light.
What grade is available?
Available in technical grade; specific higher grades may be available upon request.
Can Molekula supply it in bulk?
Yes, Molekula can supply 1-Trimethylsilylimidazole in bulk quantities—please contact sales for details.
What documentation comes with the order?
Each order includes a Certificate of Analysis (CoA) and Safety Data Sheet (SDS); additional documentation can be provided upon request.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.