Molekula
Rapamycin
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 1999 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Rapamycin is a potent immunosuppressant and mTOR inhibitor, widely used in research for its roles in cell signaling, aging studies, and anti-cancer investigations. It is also approved clinically for organ transplant rejection prevention. This macrocyclic compound has the CAS number 53123-88-9, with a molecular formula of C51H79NO13 and a molecular weight of 914.17 g/mol. It requires storage at -15 to -20°C, carries a Danger signal word for toxicity, and is supplied as a white to off-white solid.
Molekula supplies Rapamycin at ≥ 98.5% (dried basis) purity (HPLC) in 100 mg packs, from £100.56 inc. VAT. It is in stock for same-day dispatch. Every batch ships with a certificate of analysis, and safety data sheets are available in 6 languages. Larger quantities, up to multi-tonne, are quoted on request.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
In stock — same-day dispatch
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.
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100 mg — £83.80 per pack ex VAT · £100.56 inc. VAT
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White to Off-white powder |
| Water | ≤ 1.0% |
| Purity (HPLC) | ≥ 98.5% (dried basis) |
| Heavy metals | ≤ 20ppm |
| Assay | 98.0 - 102.0% |
| Optical Rotation | -147 to -157° |
| Residue on Ignition | ≤ 0.15% |
| Identification (IR) | Conforms to Reference |
| Identification (HPLC) | Conforms to Reference |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | -15 to -20 °C |
| Acidity | Neutral |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Melting Point | 183-185 °C |
| log P (octanol/water) | 4.81 |
Source: PubChem CID 5284616 (HSDB)
Identification
| Property | Value |
|---|---|
| SKU | 41676136 |
| CAS Number | 53123-88-9 |
| IUPAC Name | (1R,9S,12S,15R,16E,18R,19R,21R,23S,24E,26E,28E,30S,32S,35R)-1,18-dihydroxy-12-[(2R)-1-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]propan-2-yl]-19,30-dimethoxy-15,17,21,23,29,35-hexamethyl-11,36-dioxa-4-azatricyclo[30.3.1.04,9]hexatriaconta-16,24,26,28-tetraene-2,3,10,14,20-pentone |
| EC Number | 610-965-5 |
| Molecular Formula | C51H79NO13 |
| Molecular Weight | 914.17 |
| Exact Mass | 913.5551 |
| SMILES | C[C@@H]1CC[C@H]2C[C@@H](/C(=C/C=C/C=C/[C@H](C[C@H](C(=O)[C@@H]([C@@H](/C(=C/[C@H](C(=O)C[C@H](OC(=O)[C@@H]3CCCCN3C(=O)C(=O)[C@@]1(O2)O)[C@H](C)C[C@@H]4CC[C@H]([C@@H](C4)OC)O)C)/C)O)OC)C)C)/C)OC |
| InChIKey | QFJCIRLUMZQUOT-HPLJOQBZSA-N |
| InChI | InChI=1S/C51H79NO13/c1-30-16-12-11-13-17-31(2)42(61-8)28-38-21-19-36(7)51(60,65-38)48(57)49(58)52-23-15-14-18-39(52)50(59)64-43(33(4)26-37-20-22-40(53)44(27-37)62-9)29-41(54)32(3)25-35(6)46(56)47(63-10)45(55)34(5)24-30/h11-13,16-17,25,30,32-34,36-40,42-44,46-47,53,56,60H,14-15,18-24,26-29H2,1-10H3/b13-11+,16-12+,31-17+,35-25+/t30-,32-,33-,34-,36-,37+,38+,39+,40-,42+,43+,44-,46-,47+,51-/m1/s1 |
| PubChem CID | 5284616 |
| REACH Code | Y110 |
| HTS Code | 29349990 |
| Tariff Code | 2934999090 |
Safety & GHS
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Serious Health Hazard
GHS08
Hazard statements
- H351 Suspected of causing cancer
- H361 Suspected of damaging fertility or the unborn child
- H372 Causes damage to organs through prolonged or repeated exposure
Precautionary statements
- P260 Do not breathe dust/fume/gas/mist/vapours/spray
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P302+352 IF ON SKIN: Wash with soap and water
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
- P308+313 IF exposed or concerned: Get medical advice/attention
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Russian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Quality certificates
Molekula Group is certified to ISO 9001:2015 (quality) and ISO 14001:2015 (environmental management), audited by a UKAS-accredited body. Both certificates are valid to 17 May 2028.
Synonyms
- Antibiotic AY 22989
- FYARRO
- HYFTOR
- Npc-12g
- RAPA
- rapalimus
- Rapammune
- Rapamune
- Sirolimus
- sirolimusum
Frequently asked questions
What is rapamycin commonly used for in research and pharmaceutical applications?
Rapamycin is primarily used as an immunosuppressant in organ transplantation and as a research tool to study mTOR signaling pathways, autophagy, and aging.
What is the chemical formula and molecular weight of rapamycin?
The chemical formula is C₅₁H₇₉NO₁₃, and the molecular weight is 914.17 g/mol.
How should rapamycin be stored to maintain stability?
Rapamycin should be stored at -15 to -20°C to preserve its potency and prevent degradation.
What grades or purities of rapamycin does Molekula supply?
Molekula supplies rapamycin in research-grade purity (≥98%), suitable for laboratory and preclinical studies.
Can Molekula supply rapamycin in bulk quantities for large-scale applications?
Yes, Molekula can provide rapamycin in bulk, with quantities and packaging tailored to meet your specific research or production needs.
What documentation is provided with a rapamycin order from Molekula?
Each order includes a Certificate of Analysis (CoA), Material Safety Data Sheet (MSDS), and batch-specific documentation for traceability.
Where can I buy Rapamycin?
Directly from Molekula, which lists Rapamycin in 100 mg packs from £100.56 inc. VAT, with a certificate of analysis for every batch. Larger quantities are quoted on request. Molekula's offices: United Kingdom, France, Spain, Germany, Italy, United States and China.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.