Molekula
Homoharringtonine
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Homoharringtonine is a natural alkaloid derived from the evergreen tree Cephalotaxus harringtonia, primarily used in cancer research and clinical applications for its potent anti-leukemic properties, particularly in treating chronic myeloid leukemia. It inhibits protein synthesis by binding the A-site cleft of the peptidyl transferase centre on the large (60S) ribosomal subunit, blocking translation elongation and disrupting tumor cell growth. This compound has a CAS number of 26833-87-4, with the molecular formula C29H39NO9 and a molecular weight of 545.62 g/mol. It must be stored at -15 to -20°C and is classified with a Danger signal word due to its toxicity. Molekula supplies Homoharringtonine from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.
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10 mg — £74.00 per pack ex VAT · £88.80 inc. VAT
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Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
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Specifications
| Property | Value |
|---|---|
| Appearance | White to Pale brown Solid |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | -15 to -20 °C |
| Transport Class | 6.1 |
| Packing Group | II |
| Acidity | Neutral |
Identification
| Property | Value |
|---|---|
| SKU | 43809110 |
| CAS Number | 26833-87-4 |
| IUPAC Name | 1-O-[(2S,3S,6R)-4-methoxy-16,18-dioxa-10-azapentacyclo[11.7.0.02,6.06,10.015,19]icosa-1(20),4,13,15(19)-tetraen-3-yl] 4-O-methyl (2R)-2-hydroxy-2-(4-hydroxy-4-methylpentyl)butanedioate |
| Molecular Formula | C29H39NO9 |
| Molecular Weight | 545.62 |
| Exact Mass | 545.2625 |
| SMILES | CC(C)(CCC[C@@](CC(=O)OC)(C(=O)O[C@H]1[C@H]2C3=CC4=C(C=C3CCN5[C@@]2(CCC5)C=C1OC)OCO4)O)O |
| InChIKey | HYFHYPWGAURHIV-JFIAXGOJSA-N |
| InChI | InChI=1S/C29H39NO9/c1-27(2,33)8-5-10-29(34,16-23(31)36-4)26(32)39-25-22(35-3)15-28-9-6-11-30(28)12-7-18-13-20-21(38-17-37-20)14-19(18)24(25)28/h13-15,24-25,33-34H,5-12,16-17H2,1-4H3/t24-,25-,28+,29-/m1/s1 |
| PubChem CID | 285033 |
| UN Number | UN1544 |
| REACH Code | Y110 |
| HTS Code | 29349944 |
| Tariff Code | 2934999090 |
Safety & GHS
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Toxic
GHS06
Hazard statements
- H300 + H310 + H330 Fatal if swallowed, in contact with skin or if inhaled
Precautionary statements
- P260 Do not breathe dust/fume/gas/mist/vapours/spray
- P264 Wash thoroughly after handling
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician
- P302+352 IF ON SKIN: Wash with soap and water
- P304+312 IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell
Documents
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
- (2'R,3S,4S,5R)-(-)-homoharringtonine
- Ceflatonin
- Homoharringtonin
- mepesuccinate d'omacetaxine
- mepesuccinato de omacetaxina
- Myelostat
- Omacetaxine mepesuccinate
- omacetaxini mepesuccinas
- Omapro
- Synribo
Frequently asked questions
What is homoharringtonine used for?
Homoharringtonine is primarily used as an investigational anticancer agent, particularly in the treatment of chronic myeloid leukemia (CML) and other hematological malignancies.
What is the chemical formula and molecular weight of homoharringtonine?
The chemical formula is C₂₉H₃₉NO₉ and the molecular weight is 545.62 g/mol.
How should homoharringtonine be stored?
Store homoharringtonine at -15 to -20°C to maintain stability and potency.
What grades or purity levels of homoharringtonine does Molekula supply?
Molekula supplies homoharringtonine in pharmaceutical-grade purity, suitable for research and development applications.
Can Molekula supply homoharringtonine in bulk quantities?
Yes, Molekula can provide homoharringtonine in bulk, with quantities tailored to your research or production needs.
What documentation comes with an order of homoharringtonine?
Each order includes a Certificate of Analysis (CoA), Material Safety Data Sheet (MSDS), and batch-specific documentation for traceability.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.