Molekula
2-Cyanoethyl-N,N,N',N'-tetraisopropylphosphordiamidite (P-Reagent)
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 1999 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
2-Cyanoethyl-N,N,N',N'-tetraisopropylphosphordiamidite, commonly known as the P-Reagent, is a key reagent used in solid-phase oligonucleotide synthesis for the introduction of phosphate groups. It is a colorless to pale yellow liquid with a molecular formula of C15H32N3OP and a molecular weight of 301.41 g/mol. It is stored at temperatures between -15 and -20 °C and carries a warning signal word due to its reactivity.
Molekula supplies 2-Cyanoethyl-N,N,N',N'-tetraisopropylphosphordiamidite (P-Reagent) in 1 g and 5 g packs, from £37.32 inc. VAT. It is made or sourced to order. Every batch ships with a certificate of analysis. Larger quantities, up to multi-tonne, are quoted on request.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
On backorder — expected to ship by 5 December 2026
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.
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1 g — £31.10 per pack ex VAT · £37.32 inc. VAT
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5 g — £77.70 per pack ex VAT · £93.24 inc. VAT
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | Liquid |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | -15 to -20 °C |
| Flash Point | 48 °C |
| Transport Class | 3 |
| Packing Group | III |
| Acidity | Neutral |
Identification
| Property | Value |
|---|---|
| SKU | 23607788 |
| CAS Number | 102691-36-1 |
| Molecular Formula | {[(CH3)2CH]2N}2POCH2CH2CN |
| Molecular Weight | 301.41 |
| SMILES | CC(C)N(C(C)C)P(N(C(C)C)C(C)C)OCCC#N |
| UN Number | UN1993 |
| REACH Code | Y110 |
| HTS Code | 29299050 |
| Tariff Code | 2929909090 |
Safety & GHS
-
Flammable
GHS02
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Health Hazard
GHS07
Hazard statements
- H226 Flammable liquid and vapour
- H302 Harmful if swallowed
- H317 May cause an allergic skin reaction
- H412 Harmful to aquatic life with long lasting effects
Precautionary statements
- P210 Keep away from heat/sparks/open flames/hot surfaces - No smoking
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray
- P264 Wash thoroughly after handling
- P273 Avoid release to the environment
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
Documents
Safety Data Sheets (SDS)
We haven't published a Safety Data Sheet for this product yet. Ask us and we'll send you one.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Quality certificates
Molekula Group is certified to ISO 9001:2015 (quality) and ISO 14001:2015 (environmental management), audited by a UKAS-accredited body. Both certificates are valid to 17 May 2028.
Synonyms
No alternate names recorded for this product.
Frequently asked questions
What is 2-Cyanoethyl-N,N,N',N'-tetraisopropylphosphordiamidite used for?
It is primarily used as a phosphitylating reagent in the synthesis of oligonucleotides, particularly in solid-phase DNA and RNA synthesis.
What is the chemical formula and molecular weight?
The formula is [(CH3)2CH]2N}2POCH2CH2CN with a molecular weight of 301.41 g/mol.
How should this reagent be stored?
Store at temperatures between -15 and -20 °C to maintain stability and prevent degradation.
What grade is available?
The product specification lists its appearance as a liquid. Please contact our sales team for grade and purity details.
Can Molekula supply this reagent in bulk?
Yes, Molekula can supply this reagent in bulk quantities—please contact our sales team for pricing and availability.
What documentation comes with the order?
Each order includes a Certificate of Analysis (CoA) and Safety Data Sheet (SDS) with the shipment.
Where can I buy 2-Cyanoethyl-N,N,N',N'-tetraisopropylphosphordiamidite (P-Reagent)?
Directly from Molekula, which lists 2-Cyanoethyl-N,N,N',N'-tetraisopropylphosphordiamidite (P-Reagent) in 1 g and 5 g packs from £37.32 inc. VAT, with a certificate of analysis for every batch. Larger quantities are quoted on request. Molekula's offices: United Kingdom, France, Spain, Germany, Italy, United States and China.
Is 2-Cyanoethyl-N,N,N',N'-tetraisopropylphosphordiamidite (P-Reagent) dangerous goods for shipping?
Yes. 2-Cyanoethyl-N,N,N',N'-tetraisopropylphosphordiamidite (P-Reagent) ships as dangerous goods: UN1993, class 3, packing group III.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.