Molekula
2-Cyanoethyl-N,N,N',N'-tetraisopropylphosphordiamidite (P-Reagent)
2-Cyanoethyl-N,N,N',N'-tetraisopropylphosphordiamidite, commonly known as the P-Reagent, is a key reagent used in solid-phase oligonucleotide synthesis for the introduction of phosphate groups. It is a colorless to pale yellow liquid with a molecular formula of C14H30N4OP and a molecular weight of 301.41 g/mol. It is stored at temperatures between -15 and -20 °C and carries a warning signal word due to its reactivity. Molekula supplies 2-Cyanoethyl-N,N,N',N'-tetraisopropylphosphordiamidite from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Overview
2-Cyanoethyl-N,N,N',N'-tetraisopropylphosphordiamidite, commonly known as the P-Reagent, is a key reagent used in solid-phase oligonucleotide synthesis for the introduction of phosphate groups. It is a colorless to pale yellow liquid with a molecular formula of C14H30N4OP and a molecular weight of 301.41 g/mol. It is stored at temperatures between -15 and -20 °C and carries a warning signal word due to its reactivity. Molekula supplies 2-Cyanoethyl-N,N,N',N'-tetraisopropylphosphordiamidite from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Specifications
| Property | Value |
|---|---|
| Appearance | Liquid |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | -15 to -20 °C |
| Flash Point | 48 C |
| Transport Class | 3 |
| Packing Group | III |
| Shelf Life | 24 months |
| Acidity | Neutral |
Identification
| Property | Value |
|---|---|
| CAS Number | 102691-36-1 |
| Molecular Formula | {[(CH3)2CH]2N}2POCH2CH2CN |
| Molecular Weight | 301.41 |
| SMILES | CC(C)N(C(C)C)P(N(C(C)C)C(C)C)OCCC#N |
| EC / UN Number | 1993 |
| REACH Code | Y110 |
| HTS Code | 29299050 |
| Tariff Code | 2929909090 |
Safety & GHS
-
Explosive
GHS01
-
Oxidizing
GHS03
Hazard statements
- H226 Flammable liquid and vapour
- H302 Harmful if swallowed
- H317 May cause an allergic skin reaction
- H412 Harmful to aquatic life with long lasting effects
Precautionary statements
- P210 Keep away from heat/sparks/open flames/hot surfaces - No smoking
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray
- P264 Wash thoroughly after handling
- P273 Avoid release to the environment
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
For research and industrial use only
Documents
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Pricing & pack sizes
Synonyms
No alternate names recorded for this product.
Frequently asked questions
What is 2-Cyanoethyl-N,N,N',N'-tetraisopropylphosphordiamidite used for?
It is primarily used as a phosphitylating reagent in the synthesis of oligonucleotides, particularly in solid-phase DNA and RNA synthesis.
What is the chemical formula and molecular weight?
The formula is [(CH3)2CH]2N}2POCH2CH2CN with a molecular weight of 301.41 g/mol.
How should this reagent be stored?
Store at temperatures between -15 and -20 °C to maintain stability and prevent degradation.
What grade is available?
Available in high-purity research grade suitable for oligonucleotide synthesis.
Can Molekula supply this reagent in bulk?
Yes, Molekula can supply this reagent in bulk quantities—please contact our sales team for pricing and availability.
What documentation comes with the order?
Each order includes a Certificate of Analysis (CoA) and Safety Data Sheet (SDS) with the shipment.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.