Molekula
alpha-Amanitine
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 1999 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
Alpha-amanitin is a potent cyclic octapeptide toxin found in *Amanita* mushrooms, primarily used in research as a selective inhibitor of RNA polymerase II. It is critical for studying cellular transcription mechanisms and its effects on eukaryotic cells. This chemical has a CAS number of 23109-05-9, a molecular formula of C39H54N10O14S, and a molecular weight of 918.97 g/mol. It must be stored at -15 to -20 °C and carries a "Danger" signal word due to its extreme toxicity. Molekula supplies alpha-amanitin from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
On backorder — expected to ship by 24 November 2026
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.
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1 mg — £227.50 per pack ex VAT · £273.00 inc. VAT
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | White lyophilised solid |
| Purity | >97% |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | -15 to -20 °C |
| Transport Class | 6.1 |
| Packing Group | I |
| Acidity | Acid |
Literature values
Published physical properties of the substance, not batch specifications.
| Property | Value |
|---|---|
| Melting Point | 254-255 °C |
Source: PubChem CID 9543442 (HSDB)
Identification
| Property | Value |
|---|---|
| SKU | 34670015 |
| CAS Number | 23109-05-9 |
| IUPAC Name | 2-[(1R,4S,8R,10S,13S,16S,27R,34S)-34-[(2S)-butan-2-yl]-13-[(2R,3R)-3,4-dihydroxybutan-2-yl]-8,22-dihydroxy-2,5,11,14,27,30,33,36,39-nonaoxo-27lambda4-thia-3,6,12,15,25,29,32,35,38-nonazapentacyclo[14.12.11.06,10.018,26.019,24]nonatriaconta-18(26),19(24),20,22-tetraen-4-yl]acetamide |
| EC Number | 245-432-2 |
| Molecular Formula | C39H54N10O14S |
| Molecular Weight | 918.97 |
| Exact Mass | 918.3542 |
| SMILES | CC[C@H](C)[C@H]1C(=O)NCC(=O)N[C@H]2C[S@@](=O)C3=C(C[C@@H](C(=O)NCC(=O)N1)NC(=O)[C@@H](NC(=O)[C@@H]4C[C@H](CN4C(=O)[C@@H](NC2=O)CC(=O)N)O)[C@@H](C)[C@H](CO)O)C5=C(N3)C=C(C=C5)O |
| InChIKey | CIORWBWIBBPXCG-SXZCQOKQSA-N |
| InChI | InChI=1S/C39H54N10O14S/c1-4-16(2)31-36(60)42-11-29(55)43-25-15-64(63)38-21(20-6-5-18(51)7-22(20)46-38)9-23(33(57)41-12-30(56)47-31)44-37(61)32(17(3)27(53)14-50)48-35(59)26-8-19(52)13-49(26)39(62)24(10-28(40)54)45-34(25)58/h5-7,16-17,19,23-27,31-32,46,50-53H,4,8-15H2,1-3H3,(H2,40,54)(H,41,57)(H,42,60)(H,43,55)(H,44,61)(H,45,58)(H,47,56)(H,48,59)/t16-,17-,19+,23-,24-,25-,26-,27-,31-,32-,64+/m0/s1 |
| PubChem CID | 9543442 |
| UN Number | UN3462 |
| REACH Code | Y110 |
| HTS Code | 2934.99.4400 |
| Tariff Code | 2934999090 |
Safety & GHS
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Toxic
GHS06
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Serious Health Hazard
GHS08
Hazard statements
- H300 Fatal if swallowed
- H373 May cause damage to organs through prolonged or repeated exposure
Precautionary statements
- P260 Do not breathe dust/fume/gas/mist/vapours/spray
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician
- P303+P361+P353 IF ON SKIN (or hair): Remove/Take off immediately all contaminated clothing. Rinse skin with water/shower
- P304+312 IF INHALED: Call a POISON CENTER or doctor/physician if you feel unwell
- P307+311 IF exposed: Call a POISON CENTER or doctor/physician
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Portuguese, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Quality certificates
Molekula Group is certified to ISO 9001:2015 (quality) and ISO 14001:2015 (environmental management), audited by a UKAS-accredited body. Both certificates are valid to 17 May 2028.
Synonyms
- alpha-amanitin
- alpha-Amatoxin
- AMANITIN, .ALPHA.-
Frequently asked questions
What is alpha-Amanitine used for?
Alpha-Amanitine is primarily used in research as a potent inhibitor of RNA polymerase II, commonly employed in studies of gene expression and transcription.
What is the chemical formula and molecular weight of alpha-Amanitine?
The formula is C39H54N10O14S with a molecular weight of 918.97 g/mol.
How should alpha-Amanitine be stored?
It should be stored at temperatures between -15 and -20 °C to maintain stability and prevent degradation.
What grade of alpha-Amanitine does Molekula supply?
Molekula supplies alpha-Amanitine in research-grade purity suitable for laboratory use.
Can Molekula supply alpha-Amanitine in bulk quantities?
Yes, Molekula can supply alpha-Amanitine in bulk quantities—please contact our sales team for custom order details.
What documentation comes with an order of alpha-Amanitine?
Each order includes a Certificate of Analysis (CoA) and Safety Data Sheet (SDS) for compliance and safety purposes.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.