Molekula
tert-Butyldimethylchlorosilane (TBSCl)
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Listed pack sizes are a starting point — we manufacture, source and repack to the quantity you need
tert-Butyldimethylchlorosilane (TBSCl) is a chlorosilane reagent widely used in organic synthesis for the selective protection of alcohols and phenols as tert-butyldimethylsilyl (TBS) ethers. It enables controlled functional group masking in multi-step syntheses, pharmaceuticals, and material science applications. This white crystalline solid (CAS 18162-48-6) has the molecular formula (CH3)3CSi(CH3)2Cl and a molecular weight of 150.73 g/mol. Store at ambient conditions, but handle with caution—it carries a Danger signal word due to corrosive properties. Molekula supplies tert-Butyldimethylchlorosilane from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Example image for illustration only. Other packaging and pack sizes are available.
Pricing & pack sizes
These pack sizes aren't a limit. Molekula manufactures, sources and repacks to order — if you need 500 kg and only see 1 kg listed, . We quote from grams to multi-tonne.
Need a different size? Add the nearest pack and change the size in your basket — we price it at the same rate per unit.
-
25 g — £30.90 per pack ex VAT · £37.08 inc. VAT
-
100 g — £62.10 per pack ex VAT · £74.52 inc. VAT
Need a different quantity or pack?
Tell us how much you need and when — drums, IBCs, sacks or a one-off bulk lot. We'll manufacture or source it and come back with a price.
Prices exclude VAT/sales tax and shipping.
Specifications
| Property | Value |
|---|---|
| Appearance | Colourless crystal |
| Melting Point | 88.8 - 90.9 ℃ |
| Assay GC | ≥99% |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Flash Point | 22 °C |
| Transport Class | 4.1 (8) |
| Packing Group | II |
Identification
| Property | Value |
|---|---|
| SKU | 38882574 |
| CAS Number | 18162-48-6 |
| Molecular Formula | (CH3)3CSi(CH3)2Cl |
| Molecular Weight | 150.73 |
| SMILES | Cl[Si](C)(C)C(C)(C)C |
| UN Number | UN2925 |
| REACH Code | Y110 |
| TSCA Listed | Yes |
| HTS Code | 29319090 |
| Tariff Code | 2931900030 |
Safety & GHS
-
Flammable
GHS02
-
Corrosive
GHS05
-
Hazardous to the Environment
GHS09
Hazard statements
- H228 Flammable solid
- H314 Causes severe skin burns and eye damage
- H411 Toxic to aquatic life with long lasting effects
Precautionary statements
- P210 Keep away from heat/sparks/open flames/hot surfaces - No smoking
- P273 Avoid release to the environment
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P302+350 IF ON SKIN: Gently wash with soap and water
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
No alternate names recorded for this product.
Frequently asked questions
What is tert-Butyldimethylchlorosilane (TBSCl) commonly used for?
TBSCl is primarily used as a silylating agent in organic synthesis, particularly for protecting alcohols and phenols in TBS (tert-butyldimethylsilyl) ether formation.
What is the chemical formula and molecular weight of TBSCl?
The chemical formula is (CH₃)₃CSi(CH₃)₂Cl, and the molecular weight is 150.73 g/mol.
How should tert-Butyldimethylchlorosilane (TBSCl) be stored?
Store TBSCl at ambient temperature in a cool, dry place, away from moisture and incompatible materials.
What purity grades of TBSCl does Molekula supply?
Molekula supplies technical grade TBSCl; contact us for specific purity requirements or custom synthesis options.
Can Molekula supply tert-Butyldimethylchlorosilane (TBSCl) in bulk quantities?
Yes, we offer bulk packaging options for TBSCl; please inquire for minimum order quantities and pricing.
What documentation is provided with a TBSCl order?
Each order includes a Certificate of Analysis (CoA), Material Safety Data Sheet (MSDS), and a product specification sheet.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.