Molekula
Pretomanid
Pretomanid is a synthetic antibacterial agent used in the treatment of drug-resistant tuberculosis. It functions as a nitroimidazole prodrug that inhibits bacterial cell wall synthesis. Available with a CAS number of 187235-37-6, its molecular formula is C14H12F3N3O5 and molecular weight is 359.26 g/mol. It must be stored at temperatures between -15 and -20 °C. The substance carries a warning signal word due to potential hazards. Molekula supplies Pretomanid from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Panoramica
Pretomanid is a synthetic antibacterial agent used in the treatment of drug-resistant tuberculosis. It functions as a nitroimidazole prodrug that inhibits bacterial cell wall synthesis. Available with a CAS number of 187235-37-6, its molecular formula is C14H12F3N3O5 and molecular weight is 359.26 g/mol. It must be stored at temperatures between -15 and -20 °C. The substance carries a warning signal word due to potential hazards. Molekula supplies Pretomanid from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Specifiche
| Property | Value |
|---|---|
| Appearance | White to pale yellow powder |
| Total impurity | ≤ 1.0% |
| IR | Conforms to Reference |
| Identification | Conforms to reference |
| Water Content | ≤ 0.5% |
| Purity | 98.0-102.0% |
| Any other single impurity | ≤ 0.1% |
| HPLC | The retention time of the major peak in the chromatogram of sample corresponds to that in the chromatogram of standard preparation |
| Residual Dichloromethane | ≤ 0.06% |
| Residual Solvent Methanol | ≤ 0.3% |
| n-Heptane | ≤ 0.5% |
| Enantiomer | ≤ 0.15 |
| Methyl tert-butyl ether | ≤ 0.5% |
| Related substances PTM-2 | ≤ 0.15% |
| Related substances PTM-3A | ≤ 0.15% |
| Related substances PTM-IMP-2 | ≤ 0.15% |
| Related substances PTM-IMP-1 | ≤ 0.15% |
| Related substances PTM-IMP-4 | ≤ 0.15% |
Immagazzinamento e manipolazione
| Property | Value |
|---|---|
| Storage Temperature | -15 to -20 °C |
| Shelf Life | 24 months |
| Acidity | Neutral |
Identificazione
| Property | Value |
|---|---|
| CAS Number | 187235-37-6 |
| Molecular Formula | C14H12F3N3O5 |
| Molecular Weight | 359.26 |
| SMILES | C1[C@@H](COC2=NC(=CN21)[N+](=O)[O-])OCC3=CC=C(C=C3)OC(F)(F)F |
| REACH Code | Y110 |
| HTS Code | 29349944 |
| Tariff Code | 2934999090 |
Sicurezza e GHS
-
Health Hazard
GHS07
Dichiarazioni di pericolo
- H302 Harmful if swallowed
- H315 Causes skin irritation
- H319 Causes serious eye irritation
- H335 May cause respiratory irritation
Istruzioni di precauzione
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+312 IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell
- P302+352 IF ON SKIN: Wash with soap and water
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
- P308+313 IF exposed or concerned: Get medical advice/attention
Solo per uso di ricerca e industriale
Documenti
Certificato di Analisi (CoA) per lotto
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Prezzi e formati disponibili
Sinonimi
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Domande frequenti
What is Pretomanid used for?
Pretomanid is used in the treatment of drug-resistant tuberculosis, particularly in combination with other antibiotics as part of a regimen for multidrug-resistant TB.
What is the chemical formula and molecular weight of Pretomanid?
The chemical formula of Pretomanid is C14H12F3N3O5, and its molecular weight is 359.26 g/mol.
How should Pretomanid be stored?
Pretomanid should be stored at temperatures between -15 and -20 °C to maintain stability and prevent degradation.
What grade of Pretomanid does Molekula supply?
Molekula supplies Pretomanid in research-grade quality, suitable for laboratory use and preclinical studies.
Can Molekula supply Pretomanid in bulk quantities?
Yes, Molekula can supply Pretomanid in bulk quantities—please contact our sales team for pricing and availability.
What documentation comes with a Pretomanid order?
Each order includes a Certificate of Analysis (CoA) and safety data sheet (SDS); additional documentation can be provided upon request.
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