Molekula
Naltrexone cloridrato USP
Naltrexone hydrochloride USP Grade
Certificato ISO 9001:2015 & ISO 14001:2015 · Fornitura a laboratori e industria dal 2000 · Certificato di Analisi (CoA) per ogni lotto
Naltrexone hydrochloride USP Grade is a synthetic opioid antagonist primarily used in medicine to block the effects of opioids and alcohol, aiding in addiction treatment and recovery. It is also employed in research settings for studying opioid receptor mechanisms. This pharmaceutical-grade chemical has a CAS number of 16676-29-2, with a molecular formula of C20H23NO4 · HCl and a molecular weight of 377.86. It must be stored between 2 to 8°C and carries a signal word of Warning for safety handling. Molekula supplies Naltrexone hydrochloride USP Grade from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Panoramica
Naltrexone hydrochloride USP Grade is a synthetic opioid antagonist primarily used in medicine to block the effects of opioids and alcohol, aiding in addiction treatment and recovery. It is also employed in research settings for studying opioid receptor mechanisms. This pharmaceutical-grade chemical has a CAS number of 16676-29-2, with a molecular formula of C20H23NO4 · HCl and a molecular weight of 377.86. It must be stored between 2 to 8°C and carries a signal word of Warning for safety handling. Molekula supplies Naltrexone hydrochloride USP Grade from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Prezzi e formati disponibili
Specifiche
| Property | Value |
|---|---|
| Appearance | White or almost white powder |
| Water | 5.0% - 11.0% w/w |
| Heavy metals | ≤ 0.001% |
| Identification | IR absorption spectrum of the sample in potassium bromide dispersion should be concordant with similarly recorded spectrum of 17-(Cyclopropylmethyl),-4,5-Epoxy-3, 14-Dihdroymorphinan-6-One hydrochlorided diydrate working standard. |
| Acetone | ≤ 1000 ppm |
| Colour | Absorbance of 1 cm layer of 6.5% w/v solution in water at 420 nm should less than 0,1 An |
| Chloride (Cl-) | 9.20% - 9.58% w/w (on anhydrous and solvent free basis) |
| Solubility | Freely soluble in water, Practically insoluble in |
| Dichloromethane | ≤ 250 ppm |
| Assay (HPLC) | 98.0% - 102% w/w (on anhydrous and solvent free basis) |
| Methanol | ≤ 2000 ppm |
| Residue on Ignition | ≤ 0.1% w/w |
| Specific optical rotation | -187.0o to -197.0 o (on anhydrous and solvent free basis) |
| Ethyl acetate | ≤ 1000 ppm |
| N,N-Dimethylformamide | ≤ 200 ppm |
| Toluene | ≤ 200 ppm |
| Benzene | ≤ 2 ppm |
| Acetic acid | ≤ 1000 ppm |
| Sulphates (SO4)(2-) | ≤ 500 ppm |
| Chlorobenzene | ≤ 360 ppm |
| Cyclohexane | ≤ 1000 ppm |
| Carbon tetrachloride | ≤ 4 ppm |
| Total solvents | Sum of all solvents(from test no.: 10.1+ test no. |
| Completeness and colour of solution | Should obtain clear solution |
| Content of Didehydronaltrexone | ≤ 10 ppm |
| impurity Related compounds(by HPLC) a) Noroxymorphone | ≤ 0.50% |
| b) 10-Hydroxynaltrexone | ≤ 0.50% |
| c) Naltrexone related compound A | ≤ 0.50% |
| d) 2,2’ Bisnaltrexone | ≤ 0.50% |
| e) 10-ketonaltrexone | ≤ 0.50% |
| f) Impurity H | ≤ 0.50% |
| g) Impurity J | ≤ 0.50% |
| h) Impurity E | ≤ 0.20% |
| i) Highest unknown impurity | ≤ .10% |
| j) Total impurities | ≤ 1.50% |
| Particle size (by Malvern) | 99% Particles should below 250μm, 90% Particles should below 100μm, 50% Particles should below 50 μm |
Immagazzinamento e manipolazione
| Property | Value |
|---|---|
| Temperatura di Conservazione | 2 to 8 °C |
| Acidità | Neutral |
Identificazione
| Property | Value |
|---|---|
| SKU | 90034747 |
| Numero CAS | 16676-29-2 |
| Formula molecolare | C20H23NO4 · HCl |
| Peso molecolare | 377.86 |
| SMILES | C1CC1CN2CC[C@]34[C@@H]5C(=O)CC[C@]3([C@H]2CC6=C4C(=C(C=C6)O)O5)O.Cl |
| Codice REACH | Y110 |
| Codice HTS | 2939192000 |
| Codice doganale | 2939190000 |
Sicurezza e GHS
-
Health Hazard
GHS07
-
Serious Health Hazard
GHS08
Dichiarazioni di pericolo
- H302 Nocivo se ingerito.
- H341 Sospettato di provocare alterazioni genetiche.
Istruzioni di precauzione
- P260 Non respirare la polvere/i fumi/i gas/la nebbia/i vapori/gli aerosol.
- P280 Indossare guanti/indumenti protettivi/proteggere gli occhi/proteggere il viso.
- P301+312 IN CASO DI INGESTIONE: in presenza di malessere, contattare un CENTRO ANTIVELENI/un medico/...
- P302+352 IN CASO DI CONTATTO CON LA PELLE: lavare abbondantemente con acqua/...
- P305+351+338 IN CASO DI CONTATTO CON GLI OCCHI: sciacquare accuratamente per parecchi minuti. Togliere le eventuali lenti a contatto se è agevole farlo. Continuare a sciacquare.
Documenti
Fogli di dati di sicurezza (SDS)
Disponibile in English, French, German, Italian, Portuguese, Spanish.
Certificato di Analisi (CoA) per lotto
Inserisci un numero di lotto o di partita per recuperare il certificato di analisi relativo a tale partita. Possiamo generarlo dai dati specifici se non è disponibile alcun PDF.
Sinonimi
Nessun altro nome registrato per questo prodotto.
Domande frequenti
What is Naltrexone hydrochloride USP Grade commonly used for?
Naltrexone hydrochloride USP Grade is primarily used in the treatment of alcohol and opioid dependence, as well as for managing cravings in these conditions.
What is the chemical formula and molecular weight of Naltrexone hydrochloride?
The chemical formula is **C20H23NO4 · HCl**, and the molecular weight is **377.86 g/mol**.
How should Naltrexone hydrochloride USP Grade be stored?
Store at **2 to 8°C** to maintain stability and potency.
Does Molekula supply Naltrexone hydrochloride in bulk quantities?
Yes, Molekula can supply Naltrexone hydrochloride USP Grade in bulk, subject to regulatory compliance and order requirements.
What documentation comes with an order of Naltrexone hydrochloride USP Grade?
Each order includes a **Certificate of Analysis (CoA)**, **Material Safety Data Sheet (MSDS)**, and a **Certificate of Conformance (CoC)** to USP standards.
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