Molekula
Granisetron hydrochloride
Granisetron hydrochloride is a serotonin 5-HT3 receptor antagonist used in the prevention of chemotherapy-induced nausea and vomiting. It is available as a white to off-white crystalline powder. CAS: 107007-99-8, Molecular Formula: C18H24N4O·HCl, Molecular Weight: 348.87 g/mol. Store at ambient temperature. Signal word: Warning. Molekula supplies Granisetron hydrochloride from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Overview
Granisetron hydrochloride is a serotonin 5-HT3 receptor antagonist used in the prevention of chemotherapy-induced nausea and vomiting. It is available as a white to off-white crystalline powder. CAS: 107007-99-8, Molecular Formula: C18H24N4O·HCl, Molecular Weight: 348.87 g/mol. Store at ambient temperature. Signal word: Warning. Molekula supplies Granisetron hydrochloride from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Specifications
| Property | Value |
|---|---|
| Appearance | White to off-white powder |
| Impurity A | ≤ 1.0% |
| Impurity B | ≤ 0.5% |
| Heavy metals | ≤ 20ppm |
| pH | 4 - 6.5 |
| Impurity C | ≤ 0.2% |
| Impurity D | ≤ 0.1% |
| Loss on Drying | ≤ 0.5% |
| Solubility | Freely soluble in water, sparingly soluble in methylene chloride, slightly soluble in methanol |
| Appearance of Solution | Clear and colourless |
| Any other single impurity | ≤ 0.1% |
| Total Impurities | ≤ 1.0% |
| Assay HPLC | 97 - 102% |
| Impurity E | ≤ 0.5% |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Flash Point | 276 C |
| Shelf Life | 60 months |
| Acidity | Acid |
Identification
| Property | Value |
|---|---|
| CAS Number | 107007-99-8 |
| Molecular Formula | C18H24N4O· HCl |
| Molecular Weight | 348.87 |
| SMILES | CN1C2CCCC1CC(C2)NC(=O)C3=NN(C4=CC=CC=C43)C . HCL |
| REACH Code | Y110 |
| HTS Code | 2939790000 |
| Tariff Code | 2939799090 |
Safety & GHS
-
Explosive
GHS01
Hazard statements
- H302 Harmful if swallowed
Precautionary statements
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+312 IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell
- P302+352 IF ON SKIN: Wash with soap and water
- P304+340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
For research and industrial use only
Documents
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Pricing & pack sizes
Synonyms
No alternate names recorded for this product.
Frequently asked questions
What is Granisetron hydrochloride used for?
It is primarily used as an antiemetic to prevent nausea and vomiting caused by chemotherapy or surgery.
What is the chemical formula and molecular weight of Granisetron hydrochloride?
The formula is C18H24N4O·HCl with a molecular weight of 348.87 g/mol.
How should Granisetron hydrochloride be stored?
It should be stored at ambient temperature, protected from moisture and light.
What grade is available for Granisetron hydrochloride?
It is available in research grade; specific industrial or pharmaceutical grades are not specified.
Can Molekula supply Granisetron hydrochloride in bulk?
Yes, Molekula can supply Granisetron hydrochloride in bulk quantities—please contact sales for details.
What documentation comes with a purchase of Granisetron hydrochloride?
Each order includes a Certificate of Analysis (CoA); additional documentation such as SDS can be provided upon request.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.