Molekula
DL-Amethopterin hydrate
DL-Amethopterin hydrate is a synthetic folate antagonist used in research and pharmaceutical development, particularly in studies involving antifolate mechanisms and cancer cell metabolism. It is available with a molecular formula of C20H22N8O5, a molecular weight of 454.44 g/mol, and a CAS number of 60388-53-6. Stored at -15 to -20 °C, it is classified as Danger. Molekula supplies DL-Amethopterin hydrate from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Overview
DL-Amethopterin hydrate is a synthetic folate antagonist used in research and pharmaceutical development, particularly in studies involving antifolate mechanisms and cancer cell metabolism. It is available with a molecular formula of C20H22N8O5, a molecular weight of 454.44 g/mol, and a CAS number of 60388-53-6. Stored at -15 to -20 °C, it is classified as Danger. Molekula supplies DL-Amethopterin hydrate from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Specifications
| Property | Value |
|---|---|
| Appearance | Solid |
| Water | >10% |
| Assay | >99% |
| Optical Rotation | +20-+21 |
| Residue on Ignition | <0.5% |
| Potency | 0.4EU/mg (Endotocin) |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | -15 to -20 °C |
| Transport Class | 6.1 |
| Packing Group | III |
| Shelf Life | 24 months |
| Acidity | Acid |
Identification
| Property | Value |
|---|---|
| CAS Number | 60388-53-6 |
| Molecular Formula | C20H22N8O5 |
| Molecular Weight | 454.44 |
| SMILES | CN(CC1=CN=C2C(=N1)C(=NC(=N2)N)N)C3=CC=C(C=C3)C(=O)NC(CCC(=O)O)C(=O)O |
| EC / UN Number | 2811 |
| REACH Code | Y110 |
| HTS Code | 2933.59.9500 |
| Tariff Code | 2933599590 |
Safety & GHS
-
Flammable
GHS02
-
Corrosive
GHS05
Hazard statements
- H301 Toxic if swallowed
- H315 Causes skin irritation
- H319 Causes serious eye irritation
- H360 May damage fertility or the unborn child
Precautionary statements
- P201 Obtain special instructions before use
- P263 Avoid contact during pregnancy/while nursing
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+310 IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician
- P302+352 IF ON SKIN: Wash with soap and water
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
For research and industrial use only
Documents
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Pricing & pack sizes
Synonyms
No alternate names recorded for this product.
Frequently asked questions
What is DL-Amethopterin hydrate used for?
DL-Amethopterin hydrate is primarily used in research applications involving folate metabolism and as an inhibitor of dihydrofolate reductase (DHFR).
What is the chemical formula and molecular weight of DL-Amethopterin hydrate?
The chemical formula is C20H22N8O5, and the molecular weight is 454.44 g/mol.
How should DL-Amethopterin hydrate be stored?
It should be stored at temperatures between -15 and -20 °C to maintain stability.
What grade of DL-Amethopterin hydrate does Molekula supply?
Molekula supplies DL-Amethopterin hydrate in research-grade quality.
Can Molekula supply DL-Amethopterin hydrate in bulk quantities?
Yes, Molekula can supply DL-Amethopterin hydrate in bulk quantities—please contact our sales team for details.
What documentation comes with a purchase of DL-Amethopterin hydrate?
Each order includes a Certificate of Analysis (CoA) and safety documentation, including SDS.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.