Molekula
Hexamethylphosphoramide
Hexamethylphosphoramide (HMPA) is a polar aprotic solvent and strong ligand used in organic synthesis, particularly in nucleophilic substitution and metal-catalyzed reactions. It is a clear, colorless liquid with a molecular formula of OP[N(CH3)2]3, a molecular weight of 179.20 g/mol, and is stable at ambient storage conditions. It carries a Danger signal word due to its toxicity and environmental hazards. Molekula supplies Hexamethylphosphoramide from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Overview
Hexamethylphosphoramide (HMPA) is a polar aprotic solvent and strong ligand used in organic synthesis, particularly in nucleophilic substitution and metal-catalyzed reactions. It is a clear, colorless liquid with a molecular formula of OP[N(CH3)2]3, a molecular weight of 179.20 g/mol, and is stable at ambient storage conditions. It carries a Danger signal word due to its toxicity and environmental hazards. Molekula supplies Hexamethylphosphoramide from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Specifications
| Property | Value |
|---|---|
| Appearance | Colorless to light yellow transparent liquid |
| Water | <0.3% |
| Assay GC | >99% |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Transport Class | 8 |
| Packing Group | III |
| Shelf Life | 24 months |
| Acidity | Base |
Identification
| Property | Value |
|---|---|
| CAS Number | 680-31-9 |
| Molecular Formula | OP[N(CH3)2]3 |
| Molecular Weight | 179.20 |
| SMILES | CN(C)P(=O)(N(C)C)N(C)C |
| EC / UN Number | 3267 |
| REACH Code | Y110 |
| HTS Code | 29299050 |
| Tariff Code | 2929900090 |
Safety & GHS
-
Flammable
GHS02
-
Compressed Gas
GHS04
Hazard statements
- H303 May be harmful if swallowed
- H313 May be harmful in contact with skin
- H314 (sub cat. 1C) Causes severe skin burns and eye damage
- H340 May cause genetic defects
- H350 May cause cancer
Precautionary statements
- P260 Do not breathe dust/fume/gas/mist/vapours/spray
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+312 IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell
- P303+361 IF ON SKIN (or hair): Remove immediately all contaminated clothing. Rinse with water/shower
- P308+313 IF exposed or concerned: Get medical advice/attention
For research and industrial use only
Documents
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Pricing & pack sizes
Synonyms
No alternate names recorded for this product.
Frequently asked questions
What is Hexamethylphosphoramide used for?
It is primarily used as a polar aprotic solvent in organic synthesis and as a reagent in the preparation of phosphorus-containing compounds.
What is the chemical formula and molecular weight of Hexamethylphosphoramide?
The formula is OP[N(CH3)2]3 with a molecular weight of 179.20 g/mol.
How should Hexamethylphosphoramide be stored?
It should be stored at ambient temperature, away from moisture and incompatible materials.
What grade is available for Hexamethylphosphoramide?
Available in technical grade; specific higher grades may be available upon request.
Can Molekula supply Hexamethylphosphoramide in bulk?
Yes, bulk quantities are available; please contact our sales team for pricing and availability.
What documentation comes with an order of Hexamethylphosphoramide?
Each order includes a Certificate of Analysis and Safety Data Sheet (SDS) with the shipment.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.