Molekula
Hidrocloruro de naltrexona Grado USP
Naltrexone hydrochloride USP Grade
Certificado ISO 9001:2015 e ISO 14001:2015 · Suministro a laboratorios e industria desde el año 2000 · Certificado de Análisis (CoA) con cada lote
Naltrexone hydrochloride USP Grade is a synthetic opioid antagonist primarily used in medicine to block the effects of opioids and alcohol, aiding in addiction treatment and recovery. It is also employed in research settings for studying opioid receptor mechanisms. This pharmaceutical-grade chemical has a CAS number of 16676-29-2, with a molecular formula of C20H23NO4 · HCl and a molecular weight of 377.86. It must be stored between 2 to 8°C and carries a signal word of Warning for safety handling. Molekula supplies Naltrexone hydrochloride USP Grade from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Resumen
Naltrexone hydrochloride USP Grade is a synthetic opioid antagonist primarily used in medicine to block the effects of opioids and alcohol, aiding in addiction treatment and recovery. It is also employed in research settings for studying opioid receptor mechanisms. This pharmaceutical-grade chemical has a CAS number of 16676-29-2, with a molecular formula of C20H23NO4 · HCl and a molecular weight of 377.86. It must be stored between 2 to 8°C and carries a signal word of Warning for safety handling. Molekula supplies Naltrexone hydrochloride USP Grade from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Precios y tamaños de envase
Especificaciones
| Property | Value |
|---|---|
| Appearance | White or almost white powder |
| Water | 5.0% - 11.0% w/w |
| Heavy metals | ≤ 0.001% |
| Identification | IR absorption spectrum of the sample in potassium bromide dispersion should be concordant with similarly recorded spectrum of 17-(Cyclopropylmethyl),-4,5-Epoxy-3, 14-Dihdroymorphinan-6-One hydrochlorided diydrate working standard. |
| Acetone | ≤ 1000 ppm |
| Colour | Absorbance of 1 cm layer of 6.5% w/v solution in water at 420 nm should less than 0,1 An |
| Chloride (Cl-) | 9.20% - 9.58% w/w (on anhydrous and solvent free basis) |
| Solubility | Freely soluble in water, Practically insoluble in |
| Dichloromethane | ≤ 250 ppm |
| Assay (HPLC) | 98.0% - 102% w/w (on anhydrous and solvent free basis) |
| Methanol | ≤ 2000 ppm |
| Residue on Ignition | ≤ 0.1% w/w |
| Specific optical rotation | -187.0o to -197.0 o (on anhydrous and solvent free basis) |
| Ethyl acetate | ≤ 1000 ppm |
| N,N-Dimethylformamide | ≤ 200 ppm |
| Toluene | ≤ 200 ppm |
| Benzene | ≤ 2 ppm |
| Acetic acid | ≤ 1000 ppm |
| Sulphates (SO4)(2-) | ≤ 500 ppm |
| Chlorobenzene | ≤ 360 ppm |
| Cyclohexane | ≤ 1000 ppm |
| Carbon tetrachloride | ≤ 4 ppm |
| Total solvents | Sum of all solvents(from test no.: 10.1+ test no. |
| Completeness and colour of solution | Should obtain clear solution |
| Content of Didehydronaltrexone | ≤ 10 ppm |
| impurity Related compounds(by HPLC) a) Noroxymorphone | ≤ 0.50% |
| b) 10-Hydroxynaltrexone | ≤ 0.50% |
| c) Naltrexone related compound A | ≤ 0.50% |
| d) 2,2’ Bisnaltrexone | ≤ 0.50% |
| e) 10-ketonaltrexone | ≤ 0.50% |
| f) Impurity H | ≤ 0.50% |
| g) Impurity J | ≤ 0.50% |
| h) Impurity E | ≤ 0.20% |
| i) Highest unknown impurity | ≤ .10% |
| j) Total impurities | ≤ 1.50% |
| Particle size (by Malvern) | 99% Particles should below 250μm, 90% Particles should below 100μm, 50% Particles should below 50 μm |
Almacenamiento y manejo
| Property | Value |
|---|---|
| Temperatura de Almacenamiento | 2 to 8 °C |
| Acidez | Neutral |
Identificación
| Property | Value |
|---|---|
| SKU | 90034747 |
| Número CAS | 16676-29-2 |
| Fórmula molecular | C20H23NO4 · HCl |
| Peso molecular | 377.86 |
| SMILES | C1CC1CN2CC[C@]34[C@@H]5C(=O)CC[C@]3([C@H]2CC6=C4C(=C(C=C6)O)O5)O.Cl |
| Código REACH | Y110 |
| Código HTS | 2939192000 |
| Código arancelario | 2939190000 |
Seguridad y GHS
-
Health Hazard
GHS07
-
Serious Health Hazard
GHS08
Declaraciones de peligro
- H302 Nocivo en caso de ingestión.
- H341 Se sospecha que provoca defectos genéticos <indíquese la vía de exposición si se ha demostrado concluyentemente que el peligro no se produce por ninguna otra vía>.
Declaraciones de precaución
- P260 No respirar el polvo/el humo/el gas/la niebla/los vapores/el aerosol.
- P280 Llevar guantes/prendas/gafas/máscara de protección.
- P301+312 EN CASO DE INGESTIÓN: Llamar a un CENTRO DE TOXICOLOGÍA/médico/... si la persona se encuentra mal.
- P302+352 EN CASO DE CONTACTO CON LA PIEL: Lavar con abundante agua/...
- P305+351+338 EN CASO DE CONTACTO CON LOS OJOS: Aclarar cuidadosamente con agua durante varios minutos. Quitar las lentes de contacto, si lleva y resulta fácil. Seguir aclarando.
Documentos
Fichas de Datos de Seguridad (FDS)
Disponible en English, French, German, Italian, Portuguese, Spanish.
Certificado de Análisis (CoA) por lote
Introduzca un número de lote o partida para recuperar el informe de análisis (CoA) correspondiente a esa partida específica. Podemos generar uno a partir de los datos de especificación si no hay ningún PDF disponible.
Sinónimos
No se han registrado nombres alternativos para este producto.
Preguntas frecuentes
What is Naltrexone hydrochloride USP Grade commonly used for?
Naltrexone hydrochloride USP Grade is primarily used in the treatment of alcohol and opioid dependence, as well as for managing cravings in these conditions.
What is the chemical formula and molecular weight of Naltrexone hydrochloride?
The chemical formula is **C20H23NO4 · HCl**, and the molecular weight is **377.86 g/mol**.
How should Naltrexone hydrochloride USP Grade be stored?
Store at **2 to 8°C** to maintain stability and potency.
Does Molekula supply Naltrexone hydrochloride in bulk quantities?
Yes, Molekula can supply Naltrexone hydrochloride USP Grade in bulk, subject to regulatory compliance and order requirements.
What documentation comes with an order of Naltrexone hydrochloride USP Grade?
Each order includes a **Certificate of Analysis (CoA)**, **Material Safety Data Sheet (MSDS)**, and a **Certificate of Conformance (CoC)** to USP standards.
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