Molekula
Vonoprazan fumarate
Vonoprazan fumarate is a proton pump inhibitor used in the treatment of gastric acid-related disorders. It is available as a fumarate salt with a molecular formula of C17H16FN3O2S·C4H4O4 and a molecular weight of 461.46 g/mol. It should be stored at 2 to 8 °C. The substance carries a warning signal word. Molekula supplies Vonoprazan fumarate from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Overview
Vonoprazan fumarate is a proton pump inhibitor used in the treatment of gastric acid-related disorders. It is available as a fumarate salt with a molecular formula of C17H16FN3O2S·C4H4O4 and a molecular weight of 461.46 g/mol. It should be stored at 2 to 8 °C. The substance carries a warning signal word. Molekula supplies Vonoprazan fumarate from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Specifications
| Property | Value |
|---|---|
| Appearance | White or off-white crystal or crystalline powder |
| Melting Point | 193°C-197°C |
| Residue on ingnition | ≤0.1% |
| Heavy metals | ≤20ppm |
| Fumaric acid | 23.9-26.5% |
| Acetonitrile | ≤0.041% |
| Loss on Drying | ≤0.40% |
| Fluoride (F) | 3.7%-4.3% |
| Solubility | Slightly soluble in methanol or water and practically insoluble in isopropanol or acetonitrile |
| Assay | 98.0-102.0% (DRIED BASIS) |
| Ethanol | ≤0.5% |
| Dichloromethane | ≤0.06% |
| Methanol | ≤0.3% |
| Organic impurity | Single impurity: ≤0.15%. Total impurities: ≤1.0% |
| Ethyl acetate | ≤0.5% |
| Pyridine | ≤0.02% |
| HPLC | The retention time of the major peak of the sample solution corresponds to that of the standard solution as obtained in the assay. |
| Infrared Absorption | The infrared absorption spectrum of the sample shall be consistent with that of the reference substance |
| Benzene | ≤0.0002% |
| Acetic acid | ≤0.5% |
| N,N-dimethylacetamide | ≤0.109% |
| Tetrahydrofuran | ≤0.072% |
| N,N-diisopropylethylamine | ≤0.1% |
| Methylamine | ≤0.1% |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | 2 to 8 °C |
| Flash Point | 79 C |
| Transport Class | 9 |
| Packing Group | III |
| Shelf Life | 24 months |
| Acidity | Neutral |
Identification
| Property | Value |
|---|---|
| CAS Number | 1260141-27-2 |
| Molecular Formula | C17H16FN3O2S·C4H4O4 |
| Molecular Weight | 461.46 |
| SMILES | CNCC1=CN(C(=C1)C2=CC=CC=C2F)S(=O)(=O)C3=CN=CC=C3.C(=C/C(=O)O)\C(=O)O |
| EC / UN Number | 3077 |
| REACH Code | Y110 |
| Tariff Code | 2933399990 |
Safety & GHS
-
Explosive
GHS01
-
Flammable
GHS02
-
Toxic
GHS06
Hazard statements
- H302 + H312 + H332 Harmful if swallowed, in contact with skin or if inhaled
- H315 Causes skin irritation
- H319 Causes serious eye irritation
- H351 Suspected of causing cancer
- H373 May cause damage to organs through prolonged or repeated exposure
- H411 Toxic to aquatic life with long lasting effects
Precautionary statements
- P260 Do not breathe dust/fume/gas/mist/vapours/spray
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+312 IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell
- P302+352 IF ON SKIN: Wash with soap and water
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
- P308+313 IF exposed or concerned: Get medical advice/attention
For research and industrial use only
Documents
Certificate of Analysis (CoA) by batch
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Pricing & pack sizes
Synonyms
No alternate names recorded for this product.
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