Molekula
Trimethoprim
Trimethoprim is a synthetic antibacterial agent used primarily in combination with sulfamethoxazole to treat bacterial infections. It functions by inhibiting bacterial dihydrofolate reductase, disrupting folate metabolism. Available as a white to off-white crystalline powder, it has a CAS number of 738-70-5, molecular formula C14H18N4O3, and molecular weight of 290.32 g/mol. Store at 2 to 8 °C. Hazard classification includes signal word Danger. Molekula supplies Trimethoprim from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Overview
Trimethoprim is a synthetic antibacterial agent used primarily in combination with sulfamethoxazole to treat bacterial infections. It functions by inhibiting bacterial dihydrofolate reductase, disrupting folate metabolism. Available as a white to off-white crystalline powder, it has a CAS number of 738-70-5, molecular formula C14H18N4O3, and molecular weight of 290.32 g/mol. Store at 2 to 8 °C. Hazard classification includes signal word Danger. Molekula supplies Trimethoprim from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Specifications
| Property | Value |
|---|---|
| Appearance | A white or yellowish-white powder |
| Melting Point | 199 - 203°C |
| Heavy metals | ≤20ppm |
| Loss on Drying | ≤1.0% |
| Solubility | Very slightly soluble in water, slightly soluble in alcohol, practically insoluble in ether |
| Assay | 98.5 - 101% |
| Related Substances | ≤0.2% |
| Appearance of Solution | Not more intensely colored than reference solution BY7 |
| Sulfated ash | ≤0.1% |
| Infrared Absorption | In accordance with the spectrum of trimethoprim EPCRS |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | 2 to 8 °C |
| Transport Class | 9 |
| Packing Group | III |
| Shelf Life | 24 months |
| Acidity | Neutral |
Identification
| Property | Value |
|---|---|
| CAS Number | 738-70-5 |
| Molecular Formula | C14H18N4O3 |
| Molecular Weight | 290.32 |
| SMILES | COC1=CC(=CC(=C1OC)OC)CC2=CN=C(N=C2N)N |
| EC / UN Number | 3077 |
| REACH Code | Y110 |
| HTS Code | 29335995 |
| Tariff Code | 2933599590 |
Safety & GHS
-
Explosive
GHS01
-
Flammable
GHS02
-
Toxic
GHS06
Hazard statements
- H302 Harmful if swallowed
- H361d Suspected of damaging fertility. Suspected of damaging the unborn child.
- H373 May cause damage to organs through prolonged or repeated exposure
- H411 Toxic to aquatic life with long lasting effects
Precautionary statements
- P260 Do not breathe dust/fume/gas/mist/vapours/spray
- P273 Avoid release to the environment
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P301+312 IF SWALLOWED: Call a POISON CENTER or doctor/physician if you feel unwell
- P308+313 IF exposed or concerned: Get medical advice/attention
For research and industrial use only
Documents
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Pricing & pack sizes
Synonyms
No alternate names recorded for this product.
Frequently asked questions
What is Trimethoprim used for?
Trimethoprim is an antibiotic used to treat bacterial infections such as urinary tract infections, bronchitis, and ear infections by inhibiting bacterial dihydrofolate reductase.
What is the chemical formula and molecular weight of Trimethoprim?
The chemical formula is C14H18N4O3 and the molecular weight is 290.32 g/mol.
How should Trimethoprim be stored?
Trimethoprim should be stored at 2 to 8 °C, protected from light and moisture.
What grade of Trimethoprim does Molekula supply?
Molekula supplies Trimethoprim in research-grade purity, suitable for laboratory use.
Can Molekula supply Trimethoprim in bulk quantities?
Yes, Molekula can supply Trimethoprim in bulk quantities—please contact our sales team for pricing and availability.
What documentation comes with a Trimethoprim order?
Each order includes a Certificate of Analysis (CoA) and Safety Data Sheet (SDS); additional documentation can be provided upon request.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.