Molekula
Naltrexonhydrochlorid USP
Naltrexone hydrochloride USP Grade
ISO 9001:2015 & ISO 14001:2015 zertifiziert · Lieferant für Laboratorien und Industrie seit 2000 · Analysezertifikat (Certificate of Analysis, CoA) für jede Charge
Naltrexone hydrochloride USP Grade is a synthetic opioid antagonist primarily used in medicine to block the effects of opioids and alcohol, aiding in addiction treatment and recovery. It is also employed in research settings for studying opioid receptor mechanisms. This pharmaceutical-grade chemical has a CAS number of 16676-29-2, with a molecular formula of C20H23NO4 · HCl and a molecular weight of 377.86. It must be stored between 2 to 8°C and carries a signal word of Warning for safety handling. Molekula supplies Naltrexone hydrochloride USP Grade from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Übersicht
Naltrexone hydrochloride USP Grade is a synthetic opioid antagonist primarily used in medicine to block the effects of opioids and alcohol, aiding in addiction treatment and recovery. It is also employed in research settings for studying opioid receptor mechanisms. This pharmaceutical-grade chemical has a CAS number of 16676-29-2, with a molecular formula of C20H23NO4 · HCl and a molecular weight of 377.86. It must be stored between 2 to 8°C and carries a signal word of Warning for safety handling. Molekula supplies Naltrexone hydrochloride USP Grade from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Preise und Verpackungsgrößen
Spezifikationen
| Property | Value |
|---|---|
| Appearance | White or almost white powder |
| Water | 5.0% - 11.0% w/w |
| Heavy metals | ≤ 0.001% |
| Identification | IR absorption spectrum of the sample in potassium bromide dispersion should be concordant with similarly recorded spectrum of 17-(Cyclopropylmethyl),-4,5-Epoxy-3, 14-Dihdroymorphinan-6-One hydrochlorided diydrate working standard. |
| Acetone | ≤ 1000 ppm |
| Colour | Absorbance of 1 cm layer of 6.5% w/v solution in water at 420 nm should less than 0,1 An |
| Chloride (Cl-) | 9.20% - 9.58% w/w (on anhydrous and solvent free basis) |
| Solubility | Freely soluble in water, Practically insoluble in |
| Dichloromethane | ≤ 250 ppm |
| Assay (HPLC) | 98.0% - 102% w/w (on anhydrous and solvent free basis) |
| Methanol | ≤ 2000 ppm |
| Residue on Ignition | ≤ 0.1% w/w |
| Specific optical rotation | -187.0o to -197.0 o (on anhydrous and solvent free basis) |
| Ethyl acetate | ≤ 1000 ppm |
| N,N-Dimethylformamide | ≤ 200 ppm |
| Toluene | ≤ 200 ppm |
| Benzene | ≤ 2 ppm |
| Acetic acid | ≤ 1000 ppm |
| Sulphates (SO4)(2-) | ≤ 500 ppm |
| Chlorobenzene | ≤ 360 ppm |
| Cyclohexane | ≤ 1000 ppm |
| Carbon tetrachloride | ≤ 4 ppm |
| Total solvents | Sum of all solvents(from test no.: 10.1+ test no. |
| Completeness and colour of solution | Should obtain clear solution |
| Content of Didehydronaltrexone | ≤ 10 ppm |
| impurity Related compounds(by HPLC) a) Noroxymorphone | ≤ 0.50% |
| b) 10-Hydroxynaltrexone | ≤ 0.50% |
| c) Naltrexone related compound A | ≤ 0.50% |
| d) 2,2’ Bisnaltrexone | ≤ 0.50% |
| e) 10-ketonaltrexone | ≤ 0.50% |
| f) Impurity H | ≤ 0.50% |
| g) Impurity J | ≤ 0.50% |
| h) Impurity E | ≤ 0.20% |
| i) Highest unknown impurity | ≤ .10% |
| j) Total impurities | ≤ 1.50% |
| Particle size (by Malvern) | 99% Particles should below 250μm, 90% Particles should below 100μm, 50% Particles should below 50 μm |
Lagerung und Handhabung
| Property | Value |
|---|---|
| Lagertemperatur | 2 to 8 °C |
| Säuregehalt | Neutral |
Identifizierung
| Property | Value |
|---|---|
| SKU | 90034747 |
| CAS-Nummer | 16676-29-2 |
| Molekülformel | C20H23NO4 · HCl |
| Molekulargewicht | 377.86 |
| SMILES | C1CC1CN2CC[C@]34[C@@H]5C(=O)CC[C@]3([C@H]2CC6=C4C(=C(C=C6)O)O5)O.Cl |
| REACH-Code | Y110 |
| HTS-Code | 2939192000 |
| Zolltarifnummer | 2939190000 |
Sicherheit & GHS
-
Health Hazard
GHS07
-
Serious Health Hazard
GHS08
Gefahrenhinweise
- H302 Gesundheitsschädlich bei Verschlucken.
- H341 Kann vermutlich genetische Defekte verursachen (Expositionsweg angeben, sofern schlüssig belegt ist, dass diese Gefahr bei keinem anderen Expositionsweg besteht).
Vorsichtsmaßnahmen
- P260 Staub / Rauch / Gas / Nebel / Dampf / Aerosol nicht einatmen.
- P280 Schutzhandschuhe / Schutzkleidung / Augenschutz / Gesichtsschutz tragen.
- P301+312 Bei Verschlucken: Bei Unwohlsein Giftinformationszentrum / Arzt / … anrufen.
- P302+352 Bei Berührung mit der Haut: Mit viel Wasser / … waschen.
- P305+351+338 Bei Kontakt mit den Augen: Einige Minuten lang behutsam mit Wasser spülen. Eventuell vorhandene Kontaktlinsen nach Möglichkeit entfernen. Weiter spülen.
Dokumente
Sicherheitsdatenblätter (SDS)
Verfügbar in English, French, German, Italian, Portuguese, Spanish.
Zertifikat der Analyse (CoA) nach Charge
Geben Sie eine Chargen- oder Seriennummer ein, um die CoA für diese spezifische Charge abzurufen. Wir können eine erstellen, wenn keine PDF-Datei vorliegt, basierend auf den Spezifikationsdaten.
Synonyme
Es wurden keine alternativen Namen für dieses Produkt aufgezeichnet.
Häufig gestellte Fragen
What is Naltrexone hydrochloride USP Grade commonly used for?
Naltrexone hydrochloride USP Grade is primarily used in the treatment of alcohol and opioid dependence, as well as for managing cravings in these conditions.
What is the chemical formula and molecular weight of Naltrexone hydrochloride?
The chemical formula is **C20H23NO4 · HCl**, and the molecular weight is **377.86 g/mol**.
How should Naltrexone hydrochloride USP Grade be stored?
Store at **2 to 8°C** to maintain stability and potency.
Does Molekula supply Naltrexone hydrochloride in bulk quantities?
Yes, Molekula can supply Naltrexone hydrochloride USP Grade in bulk, subject to regulatory compliance and order requirements.
What documentation comes with an order of Naltrexone hydrochloride USP Grade?
Each order includes a **Certificate of Analysis (CoA)**, **Material Safety Data Sheet (MSDS)**, and a **Certificate of Conformance (CoC)** to USP standards.
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