Molekula
Hexamethyldisilazane sodium salt
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 1999 · Certificate of Analysis with every batch
Hexamethyldisilazane sodium salt (HMDS-Na) is a strong, non-nucleophilic amide base widely used in organic synthesis for deprotonation reactions, including the generation of ketone and ester enolates and of phosphorus ylides for Wittig olefinations. This reagent is a white to off-white solid with a molecular formula of C6H18NNaSi2 and a molecular weight of 183.37459 g/mol. It requires no special storage conditions but is classified as hazardous, carrying hazard statement H314 (causes severe skin burns and eye damage). Molekula supplies Hexamethyldisilazane sodium salt from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
This substance is available from Molekula on enquiry. Full specification, Safety Data Sheet and Certificate of Analysis documentation are provided with your quotation once our team confirms the grade and pack size you need.
Overview
- SKU
- 89966804
- CAS Number
- 1070-89-9
- IUPAC Name
- sodium bis(trimethylsilyl)azanide
- EC Number
- 213-983-8
- Molecular Formula
- C6H18NNaSi2
- Molecular Weight
- 183.37459
- Exact Mass
- 183.0875
- SMILES
- C[Si](C)(C)[N-][Si](C)(C)C.[Na+]
- InChIKey
- WRIKHQLVHPKCJU-UHFFFAOYSA-N
- InChI
- InChI=1S/C6H18NSi2.Na/c1-8(2,3)7-9(4,5)6;/h1-6H3;/q-1;+1
- PubChem CID
- 2724254
Synonyms
- N-Sodiohexamethyldisilazane
- NaHMDS
- s14980
- Silanamine, 1,1,1-trimethyl-N-(trimethylsilyl)-, sodium salt
- Silanamine, 1,1,1-trimethyl-N-(trimethylsilyl)-, sodium salt (1:1)
- sodiobis(trimethylsilyl)amine
- Sodium bis(trimethylsilyl)amide
- sodium hexamethyldisilazane
- sodium hexamethyldisilazid
- sodium;bis(trimethylsilyl)azanide
See all 3 other grades of CAS 1070-89-9 →
Frequently asked questions
What is sodium hexamethyldisilazide (NaHMDS) commonly used for in research and industry?
Sodium hexamethyldisilazide (NaHMDS) is primarily used as a strong, non-nucleophilic base in organic synthesis, particularly for deprotonation in enolate formation, generation of phosphorus ylides for Wittig reactions, and as a superbase in various transformations.
What is the chemical formula and molecular weight of sodium hexamethyldisilazide?
The chemical formula is C₆H₁₈NNaSi₂, and the molecular weight is 183.37 g/mol.
How should sodium hexamethyldisilazide be stored?
Store under ambient conditions in a tightly sealed container, protected from moisture and air, as it is sensitive to hydrolysis.
What purity grades of sodium hexamethyldisilazide does Molekula supply?
Molekula supplies sodium hexamethyldisilazide in high-purity research grade (typically ≥98%), suitable for sensitive organic synthesis applications.
Can Molekula supply sodium hexamethyldisilazide in bulk quantities?
Yes, Molekula can provide sodium hexamethyldisilazide in bulk, with quantities tailored to meet customer requirements—please contact us for specific inquiries.
What documentation is provided with an order of sodium hexamethyldisilazide?
Each order includes a Certificate of Analysis (CoA), Material Safety Data Sheet (MSDS), and a product specification sheet detailing purity, CAS number, and handling instructions.
Molekula has supplied fine chemicals and biochemicals since 1999, and its facilities are ISO 9001:2015 and ISO 14001:2015 certified. Every dispatched batch is logged with a batch number and matched to a Certificate of Analysis, and Safety Data Sheets are available in five languages.