Molekula
5-Aminoimidazole-4-carboxamide-1-B-D- ribofuranoside
Supplying 4,500+ customers in over 80 countries
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 1999 · Certificate of Analysis with every batch
5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside, commonly known as AICAR, is a cell-permeable nucleoside analogue that cells phosphorylate to ZMP (5-aminoimidazole-4-carboxamide ribonucleotide), an intermediate in de novo purine biosynthesis, and a research tool used to study cellular energy metabolism, AMPK activation, and muscle physiology. It appears as a white to off-white crystalline powder and carries hazard statements H315 (causes skin irritation), H318 (causes serious eye damage) and H319 (causes serious eye irritation). Catalogue details: CAS 2627-69-2, molecular formula C₉H₁₄N₄O₅, molecular weight 258.2313 g/mol, stored at ambient conditions. Molekula supplies 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
This substance is available from Molekula on enquiry. Full specification, Safety Data Sheet and Certificate of Analysis documentation are provided with your quotation once our team confirms the grade and pack size you need.
Overview
- SKU
- 25472253
- CAS Number
- 2627-69-2
- IUPAC Name
- 5-amino-1-[(2R,3R,4S,5R)-3,4-dihydroxy-5-(hydroxymethyl)oxolan-2-yl]imidazole-4-carboxamide
- EC Number
- 220-097-5
- Molecular Formula
- C9H14N4O5
- Molecular Weight
- 258.2313
- Exact Mass
- 258.0964
- SMILES
- C1=NC(=C(N1[C@H]2[C@@H]([C@@H]([C@H](O2)CO)O)O)N)C(=O)N
- InChIKey
- RTRQQBHATOEIAF-UUOKFMHZSA-N
- InChI
- InChI=1S/C9H14N4O5/c10-7-4(8(11)17)12-2-13(7)9-6(16)5(15)3(1-14)18-9/h2-3,5-6,9,14-16H,1,10H2,(H2,11,17)/t3-,5-,6-,9-/m1/s1
- PubChem CID
- 17513
Synonyms
- 5-Amino-1-beta-D-ribofuranosylimidazole-4-carboxamide
- 5-Amino-4-imidazolecarboxamide ribofuranoside
- Acadesina
- ACADESINE
- Acadesinum
- AIC-Riboside
- AICA-riboside
- Arasine
- GP 1-110
- Protara
Frequently asked questions
What is 5-Aminoimidazole-4-carboxamide-1-β-D-ribofuranoside (AICAR) commonly used for?
AICAR is primarily used as a research chemical to study AMP-activated protein kinase (AMPK) activation, cellular energy metabolism, and as a tool in studies of muscle growth and exercise physiology.
What is the chemical formula and molecular weight of AICAR?
The chemical formula is C₉H₁₄N₄O₅, and the molecular weight is 258.2313 g/mol.
How should AICAR be stored?
Store AICAR at ambient temperature in a dry, well-ventilated area, away from incompatible substances.
What grades or purities of AICAR does Molekula supply?
Molekula supplies research-grade AICAR with high purity (typically ≥98%), suitable for laboratory and scientific applications.
Can Molekula supply AICAR in bulk quantities?
Yes, Molekula can provide AICAR in bulk quantities upon request, subject to availability and regulatory compliance.
What documentation comes with an order of AICAR?
Each order includes a Certificate of Analysis (CoA), Material Safety Data Sheet (MSDS), and a product specification sheet detailing purity, identity, and storage instructions.
Molekula has supplied fine chemicals and biochemicals since 1999, and its facilities are ISO 9001:2015 and ISO 14001:2015 certified. Every dispatched batch is logged with a batch number and matched to a Certificate of Analysis, and Safety Data Sheets are available in five languages.