CAS Registry Number

CAS 18162-48-6 — tert-Butyldimethylchlorosilane (TBSCl)

CAS 18162-48-6 (CH3)3CSi(CH3)2Cl MW 150.73

tert-Butyldimethylchlorosilane (TBSCl) is a chlorosilane reagent widely used in organic synthesis for the selective protection of alcohols and phenols as tert-butyldimethylsilyl (TBS) ethers. It enables controlled functional group masking in multi-step syntheses, pharmaceuticals, and material science applications. This clear, volatile liquid (CAS 18162-48-6) has the molecular formula (CH3)3CSi(CH3)2Cl and a molecular weight of 150.73 g/mol. Store at ambient conditions, but handle with caution—it carries a **Danger** signal word due to corrosive properties. Molekula supplies tert-Butyldimethylchlorosilane from research to bulk quantities with full documentation and ISO 9001:2015 traceability.

Also known as: tert-Butylchlorodimethylsilane 50wt% in toluene

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Molekula products for CAS 18162-48-6

tert-Butyldimethylchlorosilane (TBSCl)

SKU 38882574

Made to order Building Blocks

tert-Butylchlorodimethylsilane 50wt% in toluene

SKU 90033102

Made to order

Molekula has supplied fine chemicals and biochemicals since 2000 from ISO 9001:2015 and ISO 14001:2015 certified facilities. Every dispatched batch is logged with a batch number and matched to a Certificate of Analysis, and Safety Data Sheets are available in five languages.