Molekula
TRIS (Tris(hydroxymethyl)aminomethane) - USP
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Certificate of Analysis with every batch
TRIS (Tris(hydroxymethyl)aminomethane) is a widely used buffering agent in biochemical and pharmaceutical applications, essential for maintaining pH stability in biological samples, cell culture media, and molecular biology experiments. It is also employed in electrophoresis and as a reagent in chemical synthesis. TRIS has a CAS number of 77-86-1, with the molecular formula NH2C(CH2OH)3 and a molecular weight of 121.14. It is stored at ambient conditions and carries a signal word of "Warning" for safety. Molekula supplies TRIS USP from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Overview
TRIS (Tris(hydroxymethyl)aminomethane) is a widely used buffering agent in biochemical and pharmaceutical applications, essential for maintaining pH stability in biological samples, cell culture media, and molecular biology experiments. It is also employed in electrophoresis and as a reagent in chemical synthesis. TRIS has a CAS number of 77-86-1, with the molecular formula NH2C(CH2OH)3 and a molecular weight of 121.14. It is stored at ambient conditions and carries a signal word of "Warning" for safety. Molekula supplies TRIS USP from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Pricing & pack sizes
Specifications
Specifications available on request — see Documents below or contact our sales team.
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Acidity | Base |
Identification
| Property | Value |
|---|---|
| SKU | 90037076 |
| CAS Number | 77-86-1 |
| Molecular Formula | NH2C(CH2OH)3 |
| Molecular Weight | 121.14 |
| SMILES | C(C(CO)(CO)N)O |
| REACH Code | Y113 |
| TSCA Listed | Yes |
| HTS Code | 29221996 |
| Tariff Code | 2922190090 |
Safety & GHS
-
Health Hazard
GHS07
Hazard statements
- H315 Causes skin irritation
- H319 Causes serious eye irritation
- H335 May cause respiratory irritation
Precautionary statements
- P261 Avoid breathing dust/fume/gas/mist/vapours/spray
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
- P308+313 IF exposed or concerned: Get medical advice/attention
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Portuguese, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
No alternate names recorded for this product.
Frequently asked questions
What is Tris(hydroxymethyl)aminomethane (TRIS) USP commonly used for?
TRIS USP is widely used as a buffer in biochemical and molecular biology applications, including pH stabilization in cell culture media, protein purification, and DNA/RNA experiments.
What is the chemical formula and molecular weight of TRIS USP?
The chemical formula is **NH₂C(CH₂OH)₃**, and the molecular weight is **121.14 g/mol**.
How should TRIS USP be stored?
Store TRIS USP at **ambient temperature** in a tightly sealed container, away from moisture and direct sunlight.
What grade of TRIS is available, and is USP the only option?
Molekula supplies **TRIS USP**, which meets pharmaceutical-grade standards. Other grades (e.g., ACS, reagent) may be available upon request.
Can Molekula supply TRIS USP in bulk quantities?
Yes, TRIS USP is available in bulk—contact our sales team for custom packaging options (e.g., 5 kg, 25 kg, or larger).
What documentation comes with a TRIS USP order?
Each order includes a **Certificate of Analysis (CoA)**, **Material Safety Data Sheet (MSDS)**, and **USP compliance documentation** for traceability.
Ready to order or need a custom pack?
Tell us the product, grade, and quantity — Molekula usually responds within one working day with pricing and lead time.