Molekula
Trifluoroacetic acid for HPLC
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Certificate of Analysis with every batch
Trifluoroacetic acid (TFA) is a strong organic acid widely used as an ion-pairing reagent in high-performance liquid chromatography (HPLC) to enhance peak symmetry and retention of polar compounds. It is also employed in peptide synthesis, organic synthesis, and as a solvent in mass spectrometry. This analytical-grade reagent has a CAS number of 76-05-1, molecular formula CF₃COOH, and a molecular weight of 114.02 g/mol. Store at ambient conditions; it carries a **Danger** signal word due to corrosive properties. Molekula supplies Trifluoroacetic acid for HPLC from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Overview
Trifluoroacetic acid (TFA) is a strong organic acid widely used as an ion-pairing reagent in high-performance liquid chromatography (HPLC) to enhance peak symmetry and retention of polar compounds. It is also employed in peptide synthesis, organic synthesis, and as a solvent in mass spectrometry. This analytical-grade reagent has a CAS number of 76-05-1, molecular formula CF₃COOH, and a molecular weight of 114.02 g/mol. Store at ambient conditions; it carries a **Danger** signal word due to corrosive properties. Molekula supplies Trifluoroacetic acid for HPLC from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Pricing & pack sizes
Specifications
| Property | Value |
|---|---|
| Appearance | Clear, colourless liquid |
| Assay/Purity | ≥ 99.5% |
| Water | ≤ 0.50% |
| Chloride (Cl-) | ≤ 0.001% |
| UV Absorption (280nm) | ≤ 0.05nm |
| Sulphates (SO4)(2-) | ≤ 0.001% |
| Fluoride (F-) | ≤ 0.005% |
| UV Absorbance (260nm) | ≤ 0.90nm |
| UV Absorbance (270nm) | ≤ 0.10nm |
| UV Absorbance (290nm) | ≤ 0.04nm |
| UV Absorbance (300nm) | ≤ 0.03nm |
| UV Absorbance (320nm) | ≤ 0.025nm |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Flash Point | 100 C |
| Transport Class | 8 |
| Packing Group | I |
| Acidity | Acid |
Identification
| Property | Value |
|---|---|
| SKU | 90035131 |
| CAS Number | 76-05-1 |
| Molecular Formula | CF3COOH |
| Molecular Weight | 114.02 |
| SMILES | O=C(O)C(F)(F)F |
| EC / UN Number | 2699 |
| REACH Code | Y110 |
| TSCA Listed | Yes |
| HTS Code | 29159018 |
| Tariff Code | 2915909043 |
Safety & GHS
-
Corrosive
GHS05
-
Health Hazard
GHS07
Hazard statements
- H314 (sub cat. 1A) Causes severe skin burns and eye damage
- H318 Causes serious eye damage
- H332 Harmful if inhaled
- H412 Harmful to aquatic life with long lasting effects
Precautionary statements
- P273 Avoid release to the environment
- P280 Wear protective gloves/protective clothing/eye protection/face protection
- P303+361 IF ON SKIN (or hair): Remove immediately all contaminated clothing. Rinse with water/shower
- P304+340 IF INHALED: Remove victim to fresh air and keep at rest in a position comfortable for breathing
- P305+351+338 IF IN EYES: Rinse with water for several minutes. Remove contact lenses if present and easy to do. Continue rinsing
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
No alternate names recorded for this product.
Frequently asked questions
What is trifluoroacetic acid (TFA) for HPLC used for?
Trifluoroacetic acid is primarily used as an ion-pairing reagent in high-performance liquid chromatography (HPLC) to improve peak shape and retention of polar or ionic compounds.
What is the chemical formula and molecular weight of trifluoroacetic acid?
The chemical formula is **CF₃COOH**, and the molecular weight is **114.02 g/mol**.
What safety classification does trifluoroacetic acid have?
Trifluoroacetic acid is labeled with the **signal word 'Danger'** due to its corrosive properties and requires careful handling.
How should trifluoroacetic acid be stored?
It should be stored at **ambient temperature** in a tightly sealed container, away from incompatible substances like bases and strong oxidizers.
Does Molekula offer trifluoroacetic acid in bulk quantities?
Yes, Molekula can supply trifluoroacetic acid in bulk, with quantities tailored to your specific requirements—please contact us for details.
What documentation is provided with an order of trifluoroacetic acid?
Each order includes a **Certificate of Analysis (CoA)**, Material Safety Data Sheet (MSDS), and a product specification sheet confirming HPLC-grade purity.
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