Molekula
2-Hydroxypropyl-beta-cyclodextrin
ISO 9001:2015 & ISO 14001:2015 certified · Supplying laboratories and industry since 2000 · Certificate of Analysis with every batch
2-Hydroxypropyl-beta-cyclodextrin (HP-β-CD) is a chemically modified cyclodextrin used primarily as a solubilizing agent, stabilizer, and drug delivery enhancer in pharmaceuticals, food, and cosmetics. It improves the bioavailability of poorly water-soluble compounds by forming inclusion complexes. This non-toxic, white to off-white powder has a CAS number of 128446-35-5 and an average molecular weight of 1400. It requires no special storage conditions and carries no signal word for hazard classification. Molekula supplies 2-Hydroxypropyl-beta-cyclodextrin from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Overview
2-Hydroxypropyl-beta-cyclodextrin (HP-β-CD) is a chemically modified cyclodextrin used primarily as a solubilizing agent, stabilizer, and drug delivery enhancer in pharmaceuticals, food, and cosmetics. It improves the bioavailability of poorly water-soluble compounds by forming inclusion complexes. This non-toxic, white to off-white powder has a CAS number of 128446-35-5 and an average molecular weight of 1400. It requires no special storage conditions and carries no signal word for hazard classification. Molekula supplies 2-Hydroxypropyl-beta-cyclodextrin from research to bulk quantities with full documentation and ISO 9001:2015 traceability.
Pricing & pack sizes
Specifications
| Property | Value |
|---|---|
| Appearance | White to off-white powder |
| Identification | Conforms to reference |
| Loss on Drying | ≤ 10.0% |
| Conductivity | 10% (w/v) water solution ≤200μS/cm |
| Other Impurity | ≤ 1.0% |
| Clarity in Solution | 50% (w/v) water solution is clear |
| Identification (IR) | same absorption bands with USP Hydroxypropyl Betadex RS |
| Conforms to USP | - |
| TYMC | ≤ 100 cfu/g |
| Residue betadex | ≤ 1.5% |
| Propylene Glycol | ≤ 2.5% |
| Propylene oxide | ≤ 1 ppm |
| TMAC (cfu/g) | ≤ 1000 cfu/g |
Storage & handling
| Property | Value |
|---|---|
| Storage Temperature | Ambient |
| Acidity | Neutral |
Identification
| Property | Value |
|---|---|
| SKU | 44405595 |
| CAS Number | 128446-35-5 |
| Molecular Formula | N/A |
| Molecular Weight | 1400 Average |
| SMILES | N/A |
| REACH Code | Y113 |
| TSCA Listed | Yes |
| HTS Code | 29400060 |
| Tariff Code | 2940000080 |
Safety & GHS
Precautionary statements
- P264 Wash thoroughly after handling
- P280 Wear protective gloves/protective clothing/eye protection/face protection
Documents
Safety Data Sheets (SDS)
Available in English, French, German, Italian, Russian, Spanish.
Certificate of Analysis (CoA) by batch
Enter a lot or batch number to retrieve the CoA for that specific batch. We can generate one from spec data if no PDF is on file.
Synonyms
No alternate names recorded for this product.
Frequently asked questions
What is 2-Hydroxypropyl-beta-cyclodextrin commonly used for?
It is primarily used as a complexing agent to improve solubility, stability, and bioavailability of poorly water-soluble drugs, flavors, and fragrances, as well as in food, pharmaceutical, and cosmetic formulations.
What is the molecular weight of 2-Hydroxypropyl-beta-cyclodextrin?
The average molecular weight is approximately 1400 g/mol.
How should 2-Hydroxypropyl-beta-cyclodextrin be stored?
Store at ambient temperature in a cool, dry place, away from direct sunlight and moisture.
What grades or purity levels of 2-Hydroxypropyl-beta-cyclodextrin does Molekula offer?
Molekula supplies high-purity grades, typically meeting pharmaceutical or food-grade standards (e.g., USP/NF or FCC compliance).
Can Molekula supply 2-Hydroxypropyl-beta-cyclodextrin in bulk quantities?
Yes, we offer bulk packaging options for 2-Hydroxypropyl-beta-cyclodextrin, with flexible quantities to meet industrial or large-scale production needs.
What documentation is provided with an order of 2-Hydroxypropyl-beta-cyclodextrin?
Each order includes a Certificate of Analysis (CoA), Material Safety Data Sheet (MSDS), and batch-specific documentation to verify purity and compliance.
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